• Issue

    Journal of Cellular and Molecular Medicine: Volume 24, Issue 7

    3763-4364
    April 2020
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ISSUE INFORMATION

Free Access

Issue Information

  • Pages: 3763-3765
  • First Published: 20 April 2020

REVIEWS

Open Access

CRISPR/Cas9-mediated genome editing: From basic research to translational medicine

Filipe V. Jacinto,  Wolfgang Link,  Bibiana I. Ferreira, 
  • Pages: 3766-3778
  • First Published: 25 February 2020
Open Access

Gadolinium-containing carbon nanomaterials for magnetic resonance imaging: Trends and challenges

Andrés Rodríguez-Galván,  Margarita Rivera,  Patricia García-López,  Luis A. Medina,  Vladimir A. Basiuk, 
  • Pages: 3779-3794
  • First Published: 10 March 2020
Open Access

Mitochondrial and mitochondrial-independent pathways of myocardial cell death during ischaemia and reperfusion injury

Sean M. Davidson,  Adriana Adameová,  Lucio Barile,  Hector Alejandro Cabrera-Fuentes,  Antigone Lazou,  Pasquale Pagliaro,  Kåre-Olav Stensløkken,  David Garcia-Dorado, on behalf of the EU-CARDIOPROTECTION COST Action (CA16225) , 
  • Pages: 3795-3806
  • First Published: 10 March 2020

ORIGINAL ARTICLES

Open Access

A risk signature with four autophagy-related genes for predicting survival of glioblastoma multiforme

Yulin Wang,  Weijiang Zhao,  Zhe Xiao,  Gefei Guan,  Xin Liu,  Minghua Zhuang, 
  • Pages: 3807-3821
  • First Published: 17 February 2020
Open Access

Long non-coding RNA LINC00467 drives hepatocellular carcinoma progression via inhibiting NR4A3

Haihao Wang,  Qiannan Guo,  Kan-Paatib Barnabo Nampoukime,  Peiwen Yang,  Ke Ma, 
  • Pages: 3822-3836
  • First Published: 03 March 2020
Open Access

C-X-C motif chemokine receptor 4 aggravates renal fibrosis through activating JAK/STAT/GSK3β/β-catenin pathway

Yahong Liu,  Qijian Feng,  Jinhua Miao,  Qinyu Wu,  Shan Zhou,  Weiwei Shen,  Yanqiu Feng,  Fan Fan Hou,  Youhua Liu,  Lili Zhou, 
  • Pages: 3837-3855
  • First Published: 02 March 2020

Open Access

Endogenous ocular lipids as potential modulators of intraocular pressure

Genea Edwards,  Jennifer Arcuri,  Haiyan Wang,  Noel Ziebarth,  Gulab Zode,  Richard K. Lee,  Sanjoy K. Bhattacharya, 
  • Pages: 3856-3900
  • First Published: 23 February 2020
Open Access

Transcriptome analyses reveal molecular mechanisms underlying phenotypic differences among transcriptional subtypes of glioblastoma

Yuan-Bo Pan,  Siqi Wang,  Biao Yang,  Zhenqi Jiang,  Cameron Lenahan,  Jianhua Wang,  Jianmin Zhang,  Anwen Shao, 
  • Pages: 3901-3916
  • First Published: 24 February 2020
Open Access

Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes

Zhe Liu,  Kun Cao,  Zebin Liao,  Yuanyuan Chen,  Xiao Lei,  Qun Wei,  Cong Liu,  Xuejun Sun,  Yanyong Yang,  Jianming Cai,  Fu Gao, 
  • Pages: 3917-3930
  • First Published: 05 March 2020
Open Access

Inhibition of PLK4 might enhance the anti-tumour effect of bortezomib on glioblastoma via PTEN/PI3K/AKT/mTOR signalling pathway

Jing Wang,  Dengpeng Ren,  Yan Sun,  Chao Xu,  Chunhong Wang,  Rui Cheng,  Lina Wang,  Guijun Jia,  Jinrui Ren,  Jiuhong Ma,  Yue Tu,  Hongming Ji, 
  • Pages: 3931-3947
  • First Published: 03 March 2020
Open Access

Dysregulated TFR and TFH cells correlate with B-cell differentiation and antibody production in autoimmune hepatitis

Ma Liang,  Zhang Liwen,  Dai Juan,  Zhuang Yun,  Ding Yanbo,  Chen Jianping, 
  • Pages: 3948-3957
  • First Published: 06 March 2020
Open Access

Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment

Kepeng Ou,  David A. Copland,  Sofia Theodoropoulou,  Sonja Mertsch,  Youjian Li,  Jian Liu,  Stefan Schrader,  Lei Liu,  Andrew D. Dick, 
  • Pages: 3958-3970
  • First Published: 06 March 2020
Open Access

Leydig-like cells derived from reprogrammed human foreskin fibroblasts by CRISPR/dCas9 increase the level of serum testosterone in castrated male rats

Hua Huang,  Liang Zhong,  Jin Zhou,  Yanping Hou,  Zhiyuan Zhang,  Xiaoyu Xing,  Jie Sun, 
  • Pages: 3971-3981
  • First Published: 11 March 2020
Open Access

Induction of apoptosis through extrinsic/intrinsic pathways and suppression of ERK/NF-κB signalling participate in anti-glioblastoma of imipramine

Fei-Ting Hsu,  I-Tsang Chiang,  Wei-Shu Wang, 
  • Pages: 3982-4000
  • First Published: 09 March 2020
Open Access

BHLHE41 suppresses MCF-7 cell invasion via MAPK/JNK pathway

Di Zhang,  Qin Zheng,  Chen Wang,  Na Zhao,  Yang Liu,  Enhua Wang, 
  • Pages: 4001-4010
  • First Published: 19 February 2020
Open Access

MiR-210-3p-EphrinA3-PI3K/AKT axis regulates the progression of oral cancer

Lin Wang,  Yong Song,  Hui Wang,  Ke Liu,  Zhe Shao,  Zhengjun Shang, 
  • Pages: 4011-4022
  • First Published: 17 March 2020
Open Access

Cistanche deserticola polysaccharide induces melanogenesis in melanocytes and reduces oxidative stress via activating NRF2/HO-1 pathway

Yibo Hu,  Jinhua Huang,  Yixiao Li,  Ling Jiang,  Yujie Ouyang,  Yumeng Li,  Lun Yang,  Xiaojiao Zhao,  Lihua Huang,  Hong Xiang,  Jing Chen,  Qinghai Zeng, 
  • Pages: 4023-4035
  • First Published: 25 February 2020
Cistanche deserticola polysaccharide induces melanogenesis in melanocytes and reduces oxidative stress via activating NRF2/HO-1 pathway

Cistanche deserticola polysaccharide (CDP) promotes melanogenesis in human epidermal melanocytes via activating mitogen-activated protein kinase (MAPK) signal pathway, then up-regulates the expression of MITF, TYR, TRP1, TRP2, and RAB27A. Otherwise, CDP can attenuate H2O2-induced oxidative stress in melanocytes via enhancing NRF2/HO-1 antioxidant pathway and scavenge intracellular ROS.

Open Access

Therapeutic effects of higenamine combined with [6]-gingerol on chronic heart failure induced by doxorubicin via ameliorating mitochondrial function

Jianxia Wen,  Lu Zhang,  Jian Wang,  Jiabo Wang,  Lifu Wang,  Ruilin Wang,  Ruisheng Li,  Honghong Liu,  Shizhang Wei,  Haotian Li,  Wenjun Zou,  Yanling Zhao, 
  • Pages: 4036-4050
  • First Published: 19 February 2020
Open Access

Reprogramming fibroblasts and peripheral blood cells from a C9ORF72 patient: A proof-of-principle study

Donatella Bardelli,  Francesca Sassone,  Claudia Colombrita,  Clara Volpe,  Valentina Gumina,  Silvia Peverelli,  Ilaria Catusi,  Antonia Ratti,  Vincenzo Silani,  Patrizia Bossolasco, 
  • Pages: 4051-4060
  • First Published: 03 March 2020
Open Access

Hydrogen exerts neuroprotection by activation of the miR-21/PI3K/AKT/GSK-3β pathway in an in vitro model of traumatic brain injury

Lu Wang,  Zhenyu Yin,  Feng Wang,  Zhaoli Han,  Yifeng Wang,  Shan Huang,  Tianpeng Hu,  Mengtian Guo,  Ping Lei, 
  • Pages: 4061-4071
  • First Published: 28 February 2020
Open Access

Association of PARP1 polymorphisms with response to chemotherapy in patients with high-risk neuroblastoma

Marianna Avitabile, Vito Alessandro Lasorsa,  Sueva Cantalupo,  Antonella Cardinale,  Flora Cimmino,  Annalaura Montella,  Dalila Capasso,  Riccardo Haupt,  Loredana Amoroso,  Alberto Garaventa,  Alessandro Quattrone,  Maria Valeria Corrias,  Achille Iolascon,  Mario Capasso, 
  • Pages: 4072-4081
  • First Published: 27 February 2020
Open Access

Hyperlipidemia inhibits the protective effect of lisinopril after myocardial infarction via activation of dendritic cells

Yuanji Ma,  Leilei Ma,  Jiaqi Ma,  Runda Wu,  Yunzeng Zou,  Junbo Ge, 
  • Pages: 4082-4091
  • First Published: 19 February 2020
Open Access

METTL3/YTHDF2 m6A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer

Haiyun Xie,  Jiangfeng Li,  Yufan Ying,  Huaqing Yan,  Ke Jin,  Xueyou Ma,  Liujia He,  Xin Xu,  Ben Liu,  Xiao Wang,  Xiangyi Zheng,  Liping Xie, 
  • Pages: 4092-4104
  • First Published: 03 March 2020
Open Access

Osthole-loaded N-octyl-O-sulfonyl chitosan micelles (NSC-OST) inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in rats

Lining Wang,  Suyang Zheng,  Guicheng Huang,  Jie Sun,  Yalan Pan,  Yuhao Si,  Pengcheng Tu,  Guihua Xu,  Yong Ma,  Yang Guo, 
  • Pages: 4105-4117
  • First Published: 03 March 2020
Open Access

Gnpat does not play an essential role in systemic iron homeostasis in murine model

Peng An,  Jiaming Wang,  Hao Wang,  Li Jiang,  Jia Wang,  Junxia Min,  Fudi Wang, 
  • Pages: 4118-4126
  • First Published: 28 February 2020
Open Access

Circ_PUM1 promotes the development of endometrial cancer by targeting the miR-136/NOTCH3 pathway

Zhi-Hong Zong,  Yao Liu,  Shuo Chen,  Yang Zhao, 
  • Pages: 4127-4135
  • First Published: 19 February 2020
Open Access

Long non-coding RNA POU6F2-AS2 promotes cell proliferation and drug resistance in colon cancer by regulating miR-377/BRD4

Guangru Xu,  Hongxing Zhu,  Jinhua Xu,  Yan Wang,  Yang Zhang,  Minghui Zhang,  Dichao Zhu, 
  • Pages: 4136-4149
  • First Published: 26 February 2020
Open Access

Serum TNFRII: A promising biomarker for predicting the risk of subcentimetre lung adenocarcinoma

Minjuan Hu,  Yanwei Zhang,  Beibei Sun,  Yuqing Lou,  Xueyan Zhang,  Huimin Wang,  Chengya Huang,  Wei Zhang,  Tianqing Chu,  Baohui Han, 
  • Pages: 4150-4156
  • First Published: 19 February 2020
Open Access

Pregnancy-associated venous insufficiency course with placental and systemic oxidative stress

Miguel A. Ortega,  Beatriz Romero,  Ángel Asúnsolo,  Clara Martínez-Vivero,  Felipe Sainz,  Coral Bravo,  Juan De León-Luis,  Melchor Álvarez-Mon,  Julia Buján,  Natalio García-Honduvilla, 
  • Pages: 4157-4170
  • First Published: 06 March 2020
Open Access

FAM46C controls antibody production by the polyadenylation of immunoglobulin mRNAs and inhibits cell migration in multiple myeloma

Ana Belén Herrero,  Dalia Quwaider,  Luis Antonio Corchete,  Maria Victoria Mateos,  Ramón García-Sanz,  Norma C. Gutiérrez, 
  • Pages: 4171-4182
  • First Published: 06 March 2020
Open Access

Arctigenin prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB axis: In vitro and in vivo studies

Shangkun Tang,  Weijun Zhou,  Xinyang Zhong,  Jianchen Xu,  Huasong Huang,  Xinnan Zheng,  Jingkang Zhang,  Shuyue Yang,  Ping Shang,  Qian Tang,  Haixiao Liu, 
  • Pages: 4183-4193
  • First Published: 24 February 2020
Open Access

Meiotic gatekeeper STRA8 regulates cell cycle by interacting with SETD8 during spermatogenesis

Changmin Niu,  Jiaqian Guo,  Xueyi Shen,  Shikun Ma,  Mengmeng Xia,  Jing Xia,  Ying Zheng, 
  • Pages: 4194-4211
  • First Published: 24 February 2020
Open Access

Different culture method changing CD105 expression in amniotic fluid MSCs without affecting differentiation ability or immune function

Ding Wang,  Nengqing Liu,  Yingjun Xie,  Bing Song,  Shu Kong,  Xiaofang Sun, 
  • Pages: 4212-4222
  • First Published: 02 March 2020
Open Access

SEZ6L2 knockdown impairs tumour growth by promoting caspase-dependent apoptosis in colorectal cancer

Ning An, Yaqin Zhao, Haitao Lan, Ming Zhang, Yuan Yin,  Cheng Yi, 
  • Pages: 4223-4232
  • First Published: 27 February 2020
Open Access

Reduction of SOST gene promotes bone formation through the Wnt/β-catenin signalling pathway and compensates particle-induced osteolysis

Zai Hang Zhang,  Xin Yu Jia,  Jing Yi Fang,  Hao Chai,  Qun Huang,  Chang She,  Peng Jia,  De Chun Geng,  Wei Xu, 
  • Pages: 4233-4244
  • First Published: 05 March 2020
Open Access

Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down-regulating CCNE2 in pancreatic ductal adenocarcinoma

Jie Yang,  Zhen Dong,  Aishu Ren,  Gang Fu,  Kui Zhang,  Changhong Li,  Xiangwei Wang,  Hongjuan Cui, 
  • Pages: 4245-4260
  • First Published: 06 March 2020
Open Access

Macrophage-derived MMP-9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits

Yajie Chen,  Ahmed Bilal Waqar,  Kazutoshi Nishijima,  Bo Ning,  Shuji Kitajima,  Fumikazu Matsuhisa,  Lu Chen,  Enqi Liu,  Tomonari Koike,  Ying Yu,  Jifeng Zhang,  Yuqing Eugene Chen,  Huijun Sun,  Jingyan Liang,  Jianglin Fan, 
  • Pages: 4261-4274
  • First Published: 03 March 2020
Open Access

Long non-coding RNA FEZF1-AS1 induced progression of ovarian cancer via regulating miR-130a-5p/SOX4 axis

Ziqian Sun,  Shouyang Gao,  Lili Xuan,  Xiaojun Liu, 
  • Pages: 4275-4285
  • First Published: 05 March 2020
Open Access

Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells

Xueke Wang,  Xiaoyan Shao,  Linaer Gu,  Ke Jiang,  Sitong Wang,  Jianhua Chen,  Juemin Fang,  Xianling Guo,  Min Yuan,  Ji Shi,  Chan Ding,  Songshu Meng,  Qing Xu, 
  • Pages: 4286-4297
  • First Published: 26 February 2020
Open Access

Hedgehog signalling mediates drug resistance through targeting TAP1 in hepatocellular carcinoma

Xiao-Tian Zhou,  Jia Ding,  Hui-Yan Li,  Jie-Liang Zuo,  Sheng-Yang Ge,  Hu-Liang Jia,  Jian Wu, 
  • Pages: 4298-4311
  • First Published: 28 February 2020
Open Access

iNOS-inhibitor driven neuroprotection in a porcine retina organ culture model

José Hurst,  Ana Maria Mueller-Buehl,  Lisa Hofmann,  Sandra Kuehn,  Fenja Herms,  Sven Schnichels,  Stephanie Christine Joachim, 
  • Pages: 4312-4323
  • First Published: 04 March 2020
Open Access

Potent USP10/13 antagonist spautin-1 suppresses melanoma growth via ROS-mediated DNA damage and exhibits synergy with cisplatin

Jia Guo,  JiangLing Zhang,  Long Liang,  Nian Liu,  Min Qi,  Shuang Zhao,  Juan Su,  Jing Liu,  Cong Peng,  Xiang Chen,  Hong Liu, 
  • Pages: 4324-4340
  • First Published: 04 March 2020
Open Access

SARI prevents ocular angiogenesis and inflammation in mice

Wenqiu Zhang,  Lei Dai,  Xun Li,  Yiming Li,  Maurice Keng Hung Yap,  Longqian Liu,  Hongxin Deng, 
  • Pages: 4341-4349
  • First Published: 02 March 2020

SHORT COMMUNICATIONS

Open Access

Differential response to hepatic differentiation stimuli of amniotic epithelial cells isolated from four regions of the amniotic membrane

Francesca Passaretta,  Domenico Bosco,  Lucia Centurione,  Maria Antonietta Centurione,  Fabio Marongiu,  Roberta Di Pietro, 
  • Pages: 4350-4355
  • First Published: 06 March 2020
Open Access

Novel mutations in ADAMTS13 CUB domains cause abnormal pre-mRNA splicing and defective secretion of ADAMTS13

Yizhi Jiang,  Dongping Huang,  Yuji Kondo,  Miao Jiang,  Zhenni Ma,  Lu Zhou,  Jian Su,  Xia Bai,  Changgeng Ruan,  Zhaoyue Wang,  Lijun Xia, 
  • Pages: 4356-4361
  • First Published: 19 February 2020

CORRIGENDUM

Open Access

Corrigendum

  • Pages: 4362-4364
  • First Published: 20 April 2020