Transfusion: Vol 59, No 4

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Transfusion: Volume 59, Issue 4

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Issue Information

Cover

Masthead and Table of Contents

EDITORIALS

Is a platelet suntan the answer?

Growing evidence supports healthy older people continuing to donate blood into later life

RAPID REVIEW

Current challenges for CAR T-cell therapy of acute myeloid leukemia

KEEP AHEAD

A monthly roundup of key articles in other journals

TRANSFUSION MEDICINE ILLUSTRATED

Severe intravascular hemolysis following extracorporeal right ventricular assist device placement

HOW DO I?

How do I support a pediatric cardiac surgery program utilizing fresh whole blood?

BRIEF REPORT

Identification of red blood cell antibodies in maternal breast milk implicated in prolonged hemolytic disease of the fetus and newborn

CASE REPORT

Production of RBC autoantibody mimicking anti-D specificity following transfusion in a patient with weak D Type 15

TRANSFUSION MEDICINE

The effect of red blood cell transfusion on iron metabolism in critically ill patients

Effect of vitamin K administration on rate of warfarin reversal

Effects of blood storage age on immune, coagulation, and nitric oxide parameters in transfused patients undergoing cardiac surgery

Influence of blood storage age on immune and coagulation parameters in critically ill transfused patients

Anemia induces gut inflammation and injury in an animal model of preterm infants

TRANSFUSION PRACTICE

Evaluating safety and cost-effectiveness of platelets stored in additive solution (PAS-F) as a hemolysis risk mitigation strategy

The impact of Daratumumab on transfusion service costs

TRANSFUSION COMPLICATIONS

Blood transfusions, blood storage, and correlation with elevated pulmonary arterial pressures

BLOOD DONORS AND BLOOD COLLECTION

Safety of blood donation by individuals over age 70 and their contribution to the blood supply in five developed countries: a BEST Collaborative group study

Determinants of blood donation willingness in the European Union: a cross-country perspective on perceived transfusion safety, concerns, and incentives

DONOR INFECTIOUS DISEASE TESTING

Duplex nucleic acid test for the detection of chikungunya and dengue RNA viruses in blood donations

Financial impact of alternative approaches to reduce bacterial contamination of platelet transfusions

CELLULAR THERAPIES

Leukoreduction system chambers are a reliable cellular source for the manufacturing of T-cell therapeutics

Stored red blood cells enhance in vivo migration of dendritic cells by promoting reactive oxygen species–induced cytoskeletal rearrangement

BLOOD COMPONENTS

Bacterial inactivation of platelet concentrates with the THERAFLEX UV-Platelets pathogen inactivation system

ROS scavenger, N-acetyl-l-cysteine and NOX specific inhibitor, VAS2870 reduce platelets apoptosis while enhancing their viability during storage

IMMUNOHEMATOLOGY

Risk of HPA-1a–immunization in HPA-1a–negative women after giving birth to an HPA-1a–positive child

Predisposing factors for anti-D immune response in D− patients with chronic liver disease transfused with D+ platelet concentrates

Development of a recombinant anti-Vel immunoglobulin M to identify Vel-negative donors

BLOOD GROUP GENOMICS

Functional analysis of novel RHD variants: splicing disruption is likely to be a common mechanism of variant D phenotype

HEMOSTASIS

Evaluation of combined idarucizumab and prothrombin complex concentrate treatment for bleeding related to dabigatran in a lethal porcine model of double trauma

REVIEW

Continuing Medical Education Program in Transfusion

Clinical applications of CRISPR-based genome editing and diagnostics

REPORT OF NEW ALLELES OR ANTIGENS

A new RhD variant allele is caused by a RhD 26 T > G mutation in a Chinese Han woman with a weak D phenotype

A case of neonatal thrombocytopenia caused by maternal alloimmunization against a new platelet antigen (Bzha, HPA-34bw) located on GPIIIa

LETTERS TO THE EDITOR

The argument(s) for lowering the US minimum required content of apheresis platelet components

Apheresis technology and bacterial contamination of platelets

Donating blood on a regular basis reduces blood pressure (in hypertensives): appearances are not deceiving

COMMITTEE REPORT

Human platelet lysate current standards and future developments

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Predisposing factors for anti-D immune response in D⁻ patients with chronic liver disease transfused with D⁺ platelet concentrates

A case of neonatal thrombocytopenia caused by maternal alloimmunization against a new platelet antigen (Bzh^a, HPA-34bw) located on GPIIIa