• Issue

    Annals of Neurology: Volume 89, Issue 5

    i-viii, 851-1055
    May 2021
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Free Access

Annals of Neurology: Volume 89, Number 5, May 2021

  • First Published: 16 April 2021

Issue Information

Free Access

Issue Information

  • Pages: i-viii
  • First Published: 16 April 2021

NeuroGenesis

Impact of Global Health Electives on Neurology Trainees

Vanessa R. Salasky MD,  Deanna Saylor MD, MHS, 
  • Pages: 851-855
  • First Published: 27 January 2021

ANA Podcasts & Webinars

ANA Investigates: Neurological Complications of COVID-19 Vaccines

Adeline L. Goss MD,  Rohini D. Samudralwar MD,  Rohit R. Das MD, MPH,  Avindra Nath MD, 
  • Pages: 856-857
  • First Published: 12 March 2021

Invited Commentary

The Changing Face of Cerebral Palsy

Ann H. Tilton MD,  Jessica S. Sanders MD, 
  • Pages: 858-859
  • First Published: 01 March 2021

Review

Adults with Cerebral Palsy Require Ongoing Neurologic Care: A Systematic Review

Sarah E. Smith BS,  Mary Gannotti PT, PhD,  Edward A. Hurvitz MD,  Frances E. Jensen MD,  Linda E. Krach MD,  Michael C. Kruer MD,  Michael E. Msall MD,  Garey Noritz MD,  Deepa S. Rajan MD,  Bhooma R. Aravamuthan MD, DPhil, 
  • Pages: 860-871
  • First Published: 07 February 2021

Research Articles

Electroencephalographic Abnormalities are Common in COVID-19 and are Associated with Outcomes

Lu Lin MD, PhD,  Abrar Al-Faraj MD,  Neishay Ayub MD,  Pablo Bravo MD,  Sudeshna Das PhD,  Lorenzo Ferlini MD,  Ioannis Karakis MD, PhD,  Jong Woo Lee MD, PhD,  Shibani S. Mukerji MD, PhD,  Christopher R. Newey DO, MS,  Jay Pathmanathan MD,  Myriam Abdennadher MD,  Charles Casassa MD,  Nicolas Gaspard MD, PhD,  Daniel M. Goldenholz MD, PhD,  Emily J. Gilmore MD,  Jin Jing PhD,  Jennifer A. Kim MD, PhD,  Eyal Y. Kimchi MD, PhD,  Harshad S. Ladha MD,  Steven Tobochnik MD,  Sahar Zafar MD,  Lawrence J. Hirsch MD,  M. Brandon Westover MD, PhD,  Mouhsin M. Shafi MD, PhD, 
  • Pages: 872-883
  • First Published: 11 March 2021
Open Access

Genetic Variation in WNT9B Increases Relapse Hazard in Multiple Sclerosis

Marijne Vandebergh MSc,  Till F. M. Andlauer PhD,  Yuan Zhou PhD,  Klara Mallants BSc,  Friederike Held MD,  Lilian Aly MD,  Bruce V. Taylor MD, PhD,  Bernhard Hemmer MD, PhD,  Bénédicte Dubois MD, PhD,  An Goris PhD, 
  • Pages: 884-894
  • First Published: 11 March 2021
Open Access

Serum Glial Fibrillary Acidic Protein: A Neuromyelitis Optica Spectrum Disorder Biomarker

Orhan Aktas MD,  Michael A. Smith PhD,  William A. Rees PhD,  Jeffrey L. Bennett MD, PhD,  Dewei She PhD,  Eliezer Katz MD,  Bruce A. C. Cree MD, PhD, MAS, on behalf of the N-MOmentum scientific group and the N-MOmentum study investigators , 
  • Pages: 895-910
  • First Published: 16 March 2021
Open Access

Noninvasive Mapping of Ripple Onset Predicts Outcome in Epilepsy Surgery

Eleonora Tamilia PhD,  Margherita A. G. Matarrese MSc,  Georgios Ntolkeras MD,  P. Ellen Grant MD,  Joseph R. Madsen MD,  Steve M. Stufflebeam MD,  Phillip L. Pearl MD,  Christos Papadelis PhD, 
  • Pages: 911-925
  • First Published: 12 March 2021

Selective Endothelial Hyperactivation of Oncogenic KRAS Induces Brain Arteriovenous Malformations in Mice

Eun S. Park PhD,  Sehee Kim PhD,  Shuning Huang PhD,  Ji Young Yoo PhD,  Jakob Körbelin PhD,  Tae Jin Lee PhD,  Balveen Kaur PhD,  Pramod K. Dash PhD,  Peng R. Chen MD,  Eunhee Kim PhD, 
  • Pages: 926-941
  • First Published: 05 March 2021
Open Access

Heritability Enrichment Implicates Microglia in Parkinson's Disease Pathogenesis

Maren Stolp Andersen MD,  Sara Bandres-Ciga PhD,  Regina H. Reynolds PhD,  John Hardy PhD,  Mina Ryten MD, PhD,  Lynne Krohn MSc,  Ziv Gan-Or MD, PhD,  Inge R. Holtman PhD,  Lasse Pihlstrøm MD, PhD,  the International Parkinson's Disease Genomics Consortium , 
  • Pages: 942-951
  • First Published: 27 January 2021

Apolipoprotein E4 Reduction with Antisense Oligonucleotides Decreases Neurodegeneration in a Tauopathy Model

Alexandra Litvinchuk PhD,  Tien-Phat V. Huynh MD, PhD,  Yang Shi PhD,  Rosemary J. Jackson PhD,  Mary B. Finn,  Melissa Manis MS,  Caroline M. Francis BA,  Ainsley C. Tran BA,  Patrick M. Sullivan PhD,  Jason D. Ulrich PhD,  Bradley T. Hyman MD, PhD,  Tracy Cole PhD,  David M. Holtzman MD, 
  • Pages: 952-966
  • First Published: 07 February 2021
Open Access

Assessing Dysferlinopathy Patients Over Three Years With a New Motor Scale

Marni B. Jacobs PhD,  Meredith K. James PT,  Linda P. Lowes PT, PhD,  Lindsay N. Alfano DPT,  Michelle Eagle PT, PhD,  Robert Muni Lofra PT,  Ursula Moore MBBChir,  Jia Feng MSc,  Laura E. Rufibach PhD,  Kristy Rose PT, PhD,  Tina Duong MPT, PhD,  Luca Bello MD, PhD,  Irene Pedrosa-Hernández PT,  Scott Holsten PT,  Chikako Sakamoto PT,  Aurélie Canal PT,  Nieves Sanchez-Aguilera Práxedes PT,  Simone Thiele PT,  Catherine Siener PT, MHS,  Bruno Vandevelde,  Brittney DeWolf PT, DPT, CCCE,  Elke Maron PT,  Michela Guglieri MD,  Jean-Yves Hogrel PhD,  Andrew M. Blamire PhD,  Pierre G. Carlier MD, PhD,  Simone Spuler MD, PhD,  John W. Day MD,  Kristi J. Jones MD, PhD,  Diana X. Bharucha-Goebel MD,  Emmanuelle Salort-Campana MD,  Alan Pestronk MD,  Maggie C. Walter MD, MA,  Carmen Paradas MD, PhD,  Tanya Stojkovic MD,  Madoka Mori-Yoshimura MD, PhD,  Elena Bravver MD,  Jordi Díaz-Manera MD, PhD,  Elena Pegoraro MD, PhD,  Jerry R. Mendell MD,  The Jain COS Consortium ,  Anna G. Mayhew PT, PhD,  Volker Straub MD, PhD, 
  • Pages: 967-978
  • First Published: 11 February 2021

Diagnostic Utility of Gold Coast Criteria in Amyotrophic Lateral Sclerosis

Andrew Hannaford MBBS,  Nathan Pavey MBBS,  Mehdi van den Bos PhD,  Nimeshan Geevasinga PhD,  Parvathi Menon PhD,  Jeremy M. Shefner MD,  Matthew C. Kiernan DSc,  Steve Vucic DSc, 
  • Pages: 979-986
  • First Published: 09 February 2021
Open Access

Onset of Preclinical Alzheimer Disease in Monozygotic Twins

Elles Konijnenberg MD, PhD,  Jori Tomassen MSc,  Anouk den Braber PhD,  Mara ten Kate MD, PhD,  Maqsood Yaqub PhD,  Sandra D. Mulder PhD,  Michel G. Nivard PhD,  Hugo Vanderstichele PhD,  Adriaan A. Lammertsma,  Charlotte E. Teunissen,  Bart N. M. van Berckel,  Dorret I. Boomsma,  Philip Scheltens,  Betty M. Tijms PhD,  Pieter Jelle Visser MD, PhD, 
  • Pages: 987-1000
  • First Published: 14 February 2021

Leucine Zipper 4 Autoantibody: A Novel Germ Cell Tumor and Paraneoplastic Biomarker

Divyanshu Dubey MD,  Thomas Kryzer AS,  Yong Guo MD, PhD,  Benjamin Clarkson PhD,  John C. Cheville MD,  Brian A. Costello MD,  Bradley C. Leibovich MD,  Alicia Algeciras-Schimnich PhD,  Claudia Lucchinnetti MD,  M. Bakri Hammami MD,  Andrew M. Knight PhD,  Charles Howe PhD,  Vanda A. Lennon MD, PhD,  Andrew McKeon MD,  Sean J. Pittock MD, 
  • Pages: 1001-1010
  • First Published: 14 February 2021

Early Predictors of 9-Year Disability in Pediatric Multiple Sclerosis

Ermelinda De Meo MD,  Raffaello Bonacchi MD,  Lucia Moiola MD,  Bruno Colombo MD,  Francesca Sangalli MD,  Chiara Zanetta MD,  Maria Pia Amato MD,  Vittorio Martinelli MD,  Maria Assunta Rocca MD,  Massimo Filippi MD, 
  • Pages: 1011-1022
  • First Published: 17 February 2021

Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy

Ian C. Wenker PhD,  Frida A. Teran,  Eric R. Wengert,  Pravin K. Wagley MS,  Payal S. Panchal,  Elizabeth A. Blizzard,  Priyanka Saraf,  Jacy L. Wagnon PhD,  Howard P. Goodkin MD, PhD,  Miriam H. Meisler PhD,  George B. Richerson MD, PhD,  Manoj K. Patel PhD, 
  • Pages: 1023-1035
  • First Published: 18 February 2021

Brief Communications

Age-Related Cognitive Changes as a Function of CAG Repeat in Child and Adolescent Carriers of Mutant Huntingtin

Jordan L. Schultz PharmD,  Ellen van der Plas PhD,  Douglas R. Langbehn MD, PhD,  Amy L. Conrad PhD,  Peg C. Nopoulos MD, 
  • Pages: 1036-1040
  • First Published: 31 January 2021

Inflammatory Cytokine Patterns Associated with Neurological Diseases in Coronavirus Disease 2019

Otávio M. Espíndola PhD,  Yago C. P. Gomes MSc,  Carlos Otávio Brandão MD, PhD,  Rafael C. Torres PhD,  Marilda Siqueira PhD,  Cristiane N. Soares PhD,  Marco Antonio S. D. Lima PhD,  Ana Claudia C. B. Leite PhD,  Carolina O. Venturotti MD,  Ana Julia C. Carvalho MD,  Guilherme Torezani MD,  Abelardo Q. C. Araujo MD, PhD,  Marcus Tulius T. Silva MD, PhD, 
  • Pages: 1041-1045
  • First Published: 06 February 2021
Open Access

Depression and Nigral Neuron Density in Lewy Body Spectrum Diseases

Laura Saari MD,  Lauri Heiskanen MD,  Maria Gardberg MD, PhD,  Valtteri Kaasinen MD, PhD, 
  • Pages: 1046-1050
  • First Published: 09 February 2021

Neuro-Images

Free Access

Functional Imaging of Bow Hunter's Syndrome

Menno R. Germans MD, PhD,  Juliane Schweizer MD,  Zsolt Kulcsar MD, 
  • Pages: 1051-1052
  • First Published: 20 January 2021
Free Access

Biceps Activity Synchronous with Inspiration After Phrenic Nerve Transfer

Alex Rebello MD, DM,  Neeraj Balaini MD, DM,  Sunil Gaba MS, MCh,  Karthik Vinay Mahesh MD, DM, 
  • Pages: 1053-1054
  • First Published: 18 January 2021

Correction

Free Access

Corrigendum for “Vision Therapy: Ocular Motor Training in Mild Traumatic Brain Injury”

Jason J. S. Barton MD, PhD, FRCPC,  Paul J. Ranalli MD, FRCPC, 
  • Page: 1055
  • First Published: 16 March 2021