• Issue

    Annals of Neurology: Volume 84, Issue 2

    i-v, 165-330
    August 2018
Previous Issue|Next Issue
Export Citation(s)Download PDF(s)

Cover Image

Free Access

Annals of Neurology: Volume 84, Number 2, August 2018

  • First Published: 14 September 2018

Issue Information

Free Access

Issue Information

  • Pages: i-v
  • First Published: 14 September 2018

NeuroGenesis

Women in neurology: A WIN–Win

Suma Shah MD, 
  • Pages: 165-167
  • First Published: 16 July 2018

Neurology Grand Rounds

Multicrossover Randomized Controlled Trial Designs in Alzheimer Disease

Steven E. Arnold MD,  Rebecca A. Betensky PhD, 
  • Pages: 168-175
  • First Published: 16 July 2018

Invited Commentary

Open Access

Mendelian randomization: Progressing towards understanding causality

Inke R. König PhD,  Fabiola M. Del Greco PhD, 
  • Pages: 176-177
  • First Published: 16 July 2018

Research Articles

Plasma urate and risk of Parkinson's disease: A mendelian randomization study

Camilla J. Kobylecki MD, PhD,  Børge G. Nordestgaard MD, DMSc,  Shoaib Afzal MD, PhD, 
  • Pages: 178-190
  • First Published: 16 July 2018
Open Access

Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease

Demis A. Kia BSc,  Alastair J. Noyce PhD,  Jon White PhD,  Doug Speed PhD,  Aude Nicolas PhD,  IPDGC collaborators ,  Stephen Burgess PhD,  Debbie A. Lawlor PhD,  George Davey Smith MD,  Andrew Singleton PhD,  Mike A. Nalls PhD,  Reecha Sofat MRCP,  Nicholas W. Wood PhD, 
  • Pages: 191-199
  • First Published: 16 July 2018

Haploinsufficiency of CUX1 Causes Nonsyndromic Global Developmental Delay With Possible Catch-up Development

Konrad Platzer MD,  Benjamin Cogné PharmD,  Jennifer Hague MBBS,  Carlo L. Marcelis MD,  Diana Mitter MD,  Katrin Oberndorff MD,  Soo-Mi Park PhD,  Hans K. Ploos van Amstel PhD,  Ingrid Simonic PhD,  Jasper J. van der Smagt MD, PhD,  Alexander P.A. Stegmann PhD,  Servi J.C. Stevens PhD,  Constance T.R.M. Stumpel MD, PhD,  Marie Vincent MD,  Johannes R. Lemke MD,  Rami Jamra MD, 
  • Pages: 200-207
  • First Published: 16 July 2018

A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain

Takayuki Fujii MD,  Ryo Yamasaki MD, PhD,  Kyoko Iinuma MS,  Daisuke Tsuchimoto PhD,  Yoshinori Hayashi PhD,  Ban-yu Saitoh MD,  Takuya Matsushita MD, PhD,  Mizuho A. Kido DDS, PhD,  Shinichi Aishima MD, PhD,  Hiroshi Nakanishi PhD,  Yusaku Nakabeppu DVM, PhD,  Jun-ichi Kira MD, PhD, 
  • Pages: 208-224
  • First Published: 16 July 2018

The Charcot–Marie–Tooth Health Index: Evaluation of a Patient-Reported Outcome

Nicholas E. Johnson MD, MS-CI,  Chad Heatwole MD, MS-CI,  Peter Creigh MD,  Michael P. McDermott PhD,  Nuran Dilek MS,  Man Hung PhD,  Jerry Bounsanga BS,  Wan Tang PhD,  Michael E. Shy MD,  David N. Herrmann MBBCh, 
  • Pages: 225-233
  • First Published: 16 July 2018

Long-range genomic regulators of THBS1 and LTBP4 modify disease severity in duchenne muscular dystrophy

Robert B. Weiss PhD,  Veronica J. Vieland PhD,  Diane M. Dunn BS,  Yuuki Kaminoh BS,  Kevin M. Flanigan MD,  for the United Dystrophinopathy Project , 
  • Pages: 234-245
  • First Published: 16 July 2018

Notch3ECD immunotherapy improves cerebrovascular responses in CADASIL mice

Lamia Ghezali PhD,  Carmen Capone PhD,  Céline Baron-Menguy PhD,  Julien Ratelade PhD,  Søren Christensen PhD,  Lars Østergaard Pedersen PhD,  Valérie Domenga-Denier,  Jan Torleif Pedersen PhD,  Anne Joutel MD, PhD, 
  • Pages: 246-259
  • First Published: 16 July 2018

Clinical validation of blood/brain glutamate grabbing in acute ischemic stroke

Andrés da Silva-Candal BsC,  Amparo Pérez-Díaz PhD,  María Santamaría MD, PhD,  Clara Correa-Paz BsC,  Manuel Rodríguez-Yáñez MD, PhD,  Ana Ardá PhD,  María Pérez-Mato PhD,  Ramón Iglesias-Rey PhD,  José Brea PhD,  Jhonny Azuaje PhD,  Eddy Sotelo PhD,  Tomás Sobrino PhD,  M. Isabel Loza PhD,  José Castillo MD, PhD,  Francisco Campos PhD, 
  • Pages: 260-273
  • First Published: 16 July 2018
Open Access

Natural History of Vanishing White Matter

Eline M. C. Hamilton MD,  Hannemieke D. W. van der Lei MD, PhD,  Gerre Vermeulen MD,  Jan A. M. Gerver MD,  Charles M. Lourenço MD,  Sakkubai Naidu MD,  Hanna Mierzewska MD, PhD,  Reinoud J. B. J. Gemke MD, PhD,  Henrica C. W. de Vet PhD,  Bernard M. J. Uitdehaag MD, PhD,  Birgit I. Lissenberg-Witte PhD,  VWM Research Group ,  Marjo S. van der Knaap MD, PhD, 
  • Pages: 274-288
  • First Published: 16 July 2018
Open Access

Subcellular origin of mitochondrial DNA deletions in human skeletal muscle

Amy E. Vincent PhD,  Hannah S. Rosa PhD,  Kamil Pabis MRes,  Conor Lawless PhD,  Chun Chen MBBS, MRes,  Anne Grünewald PhD,  Karolina A. Rygiel PhD,  Mariana C. Rocha PhD,  Amy K. Reeve PhD,  Gavin Falkous MSc,  Valentina Perissi PhD,  Kathryn White PhD,  Tracey Davey,  Basil J. Petrof MD, FRCP,  Avan A. Sayer PhD, FRCP,  Cyrus Cooper DM, FRCP,  David Deehan MD, FRCS,  Robert W. Taylor PhD, FRCPath,  Doug M. Turnbull PhD, FRCP,  Martin Picard PhD, 
  • Pages: 289-301
  • First Published: 16 July 2018

Sustainable method for Alzheimer dementia prediction in mild cognitive impairment: Electroencephalographic connectivity and graph theory combined with apolipoprotein E

Dr Fabrizio Vecchio PhD,  Dr Francesca Miraglia PhD,  Dr Francesco Iberite,  Dr Giordano Lacidogna,  Dr Valeria Guglielmi,  Dr Camillo Marra,  Dr Patrizio Pasqualetti,  Dr Francesco Danilo Tiziano,  Prof Paolo Maria Rossini, 
  • Pages: 302-314
  • First Published: 16 July 2018

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein

Melania Spadaro PhD,  Stephan Winklmeier MSc,  Eduardo Beltrán PhD,  Caterina Macrini MSc,  Romana Höftberger MD,  Elisabeth Schuh MD, PhD,  Franziska S. Thaler MD,  Lisa Ann Gerdes MD,  Sarah Laurent MD, PhD,  Ramona Gerhards MSc,  Simone Brändle PhD,  Klaus Dornmair PhD,  Constanze Breithaupt PhD,  Markus Krumbholz MD,  Markus Moser PhD,  Gurumoorthy Krishnamoorthy PhD,  Frits Kamp PhD,  Dieter Jenne MD,  Reinhard Hohlfeld MD,  Tania Kümpfel MD,  Hans Lassmann MD,  Naoto Kawakami PhD,  Edgar Meinl MD, 
  • Pages: 315-328
  • First Published: 16 July 2018

Letter to the Editor

Women on multiple sclerosis clinical trial steering committees

Joseph Moneim BA Hons,  Alasdair Coles FRCP, PhD,  Gavin Giovannoni MBBCh, PhD,  Rachel Horne BA, MS, MA,  Oliver Carr BA, Hons, 
  • Pages: 329-330
  • First Published: 31 July 2018