• Issue

    Epilepsia: Volume 61, Issue 3

    i-vi, 359-588, e17-e22, 589-593
    March 2020
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ISSUE INFORMATION

Free Access

Issue Information

  • Pages: i-vi
  • First Published: 20 March 2020

CRITICAL REVIEW AND INVITED COMMENTARY

Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?

Pavel Klein,  Alon Friedman,  Mustafa Q. Hameed,  Rafal M. Kaminski,  Guy Bar-Klein,  Henrik Klitgaard,  Mathias Koepp,  Sergiusz Jozwiak,  David A. Prince,  Alexander Rotenberg,  Roy Twyman,  Annamaria Vezzani,  Michael Wong,  Wolfgang Löscher, 
  • Pages: 359-386
  • First Published: 20 March 2020

FULL-LENGTH ORIGINAL RESEARCH

Biological concepts in human sodium channel epilepsies and their relevance in clinical practice

Andreas Brunklaus,  Juanjiangmeng Du,  Felix Steckler,  Ismael I. Ghanty,  Katrine M. Johannesen,  Christina Dühring Fenger,  Stephanie Schorge,  David Baez-Nieto,  Hao-Ran Wang,  Andrew Allen,  Jen Q. Pan,  Holger Lerche,  Henrike Heyne,  Joseph D. Symonds,  Sameer M. Zuberi,  Stephan Sanders,  Beth R. Sheidley,  Dana Craiu,  Heather E. Olson,  Sarah Weckhuysen,  Peter DeJonge,  Ingo Helbig,  Hilde Van Esch,  Tiffany Busa,  Matthieu Milh,  Bertrand Isidor,  Christel Depienne,  Annapurna Poduri,  Arthur J. Campbell,  Jordane Dimidschstein,  Rikke S. Møller,  Dennis Lal, 
  • Pages: 387-399
  • First Published: 23 February 2020

Exacerbation of hepatic cirrhosis may trigger admission for epilepsy and status epilepticus

Jonathan M. Gursky,  Kyle C. Rossi,  Nathalie Jetté,  Mandip S. Dhamoon, 
  • Pages: 400-407
  • First Published: 24 January 2020
Open Access

Mesial temporal resection following long-term ambulatory intracranial EEG monitoring with a direct brain-responsive neurostimulation system

Lawrence J. Hirsch,  Emily A. Mirro,  Vicenta Salanova,  Thomas C. Witt,  Cornelia N. Drees,  Mesha-Gay Brown,  Ricky W. Lee,  Toni L. Sadler,  Elizabeth A. Felton,  Paul Rutecki,  Hae Won Shin,  Eldad Hadar,  Manu Hegde,  Vikram R. Rao,  Lilit Mnatsakanyan,  Deepak S. Madhavan,  Tarek J. Zakaria,  Anli A. Liu,  Christianne N. Heck,  Janet E. Greenwood,  Jeffrey K. Bigelow,  Dileep R. Nair,  Andreas V. Alexopoulos,  Michael Mackow,  Jonathan C. Edwards,  Nadia Sotudeh,  Ruben I. Kuzniecky,  Ryder P. Gwinn,  Michael J. Doherty,  Eric B. Geller,  Martha J. Morrell, 
  • Pages: 408-420
  • First Published: 18 February 2020
Open Access

Same same but different: A Web-based deep learning application revealed classifying features for the histopathologic distinction of cortical malformations

Joshua Kubach,  Angelika Muhlebner-Fahrngruber,  Figen Soylemezoglu,  Hajime Miyata,  Pitt Niehusmann,  Mrinalini Honavar,  Fabio Rogerio,  Se-Hoon Kim,  Eleonora Aronica,  Rita Garbelli,  Samuel Vilz,  Alexander Popp,  Stefan Walcher,  Christoph Neuner,  Michael Scholz,  Stefanie Kuerten,  Verena Schropp,  Sebastian Roeder,  Philip Eichhorn,  Markus Eckstein,  Axel Brehmer,  Katja Kobow,  Roland Coras,  Ingmar Blumcke,  Samir Jabari, 
  • Pages: 421-432
  • First Published: 20 February 2020
Open Access

MRI profiling of focal cortical dysplasia using multi-compartment diffusion models

Sara Lorio,  Sophie Adler,  Roxana Gunny,  Felice D’Arco,  Enrico Kaden,  Konrad Wagstyl,  Thomas S. Jacques,  Chris A. Clark,  Judith Helen Cross,  Torsten Baldeweg,  David W. Carmichael, 
  • Pages: 433-444
  • First Published: 17 February 2020

Treatment initiation decisions in newly diagnosed epilepsy–A longitudinal cohort study

Sameer Sharma,  Zhibin Chen,  Maria Rychkova,  John Dunne,  Judy Lee,  Linda Kalilani,  Nicholas Lawn,  Patrick Kwan, 
  • Pages: 445-454
  • First Published: 04 February 2020
Open Access

Bioavailability and safety of diazepam intranasal solution compared to oral and rectal diazepam in healthy volunteers

R. Edward Hogan,  Barry E. Gidal,  Barry Koplowitz,  Luana P. Koplowitz,  Richard E. Lowenthal,  Enrique Carrazana, 
  • Pages: 455-464
  • First Published: 17 February 2020

Long-term outcomes of reoperations in epilepsy surgery

Ruta Yardi,  Marcia E. Morita-Sherman,  Zachary Fitzgerald,  Vineet Punia,  James Bena,  Shannon Morrison,  Imad Najm,  William Bingaman,  Lara Jehi, 
  • Pages: 465-478
  • First Published: 27 February 2020

Accidental deaths in young people with epilepsy and psychiatric comorbidity—A Danish nationwide cohort study

Sissel K. Aagaard,  Julie W. Dreier,  Yuelian Sun,  Thomas M. Laursen,  Jakob Christensen, 
  • Pages: 479-488
  • First Published: 18 February 2020
Open Access

Predictors of focal to bilateral tonic-clonic seizures during long-term video-EEG monitoring

Max C. Pensel,  Martin Schnuerch,  Christian E. Elger,  Rainer Surges, 
  • Pages: 489-497
  • First Published: 18 February 2020

Development of a model to predict electroencephalographic seizures in critically ill children

France W. Fung,  Marin Jacobwitz,  Darshana S. Parikh,  Lisa Vala,  Maureen Donnelly,  Jiaxin Fan,  Rui Xiao,  Alexis A. Topjian,  Nicholas S. Abend, 
  • Pages: 498-508
  • First Published: 20 February 2020
Open Access

Early epilepsy in children with Zika-related microcephaly in a cohort in Recife, Brazil: Characteristics, electroencephalographic findings, and treatment response

Maria Durce C. G. Carvalho,  Ricardo A. A. Ximenes,  Ulisses R. Montarroyos,  Paula F. S. da Silva,  Luciana P. A. Andrade-Valença,  Sophie H. Eickmann,  Regina C. Ramos,  Maria Ângela W. Rocha,  Thalia V. B. de Araujo,  Maria de Fátima P. M. de Albuquerque,  Celina M. T. Martelli,  Wayner V. de Souza,  Elizabeth B. Brickley,  Demócrito de B. Miranda-Filho,  on behalf of the Microcephaly Epidemic Research Group , 
  • Pages: 509-518
  • First Published: 17 February 2020

Mortality and morbidity of patients with treated and untreated epilepsy in New Zealand

Kristen Joy Hamilton,  Zhibin Chen,  Andrew Tomlin,  Patrick Kwan, 
  • Pages: 519-527
  • First Published: 24 January 2020

Quantitative readability analysis of websites providing information on traumatic brain injury and epilepsy: A need for clear communication

Daniel José Correa,  Lindsey Milano,  Churl-Su Kwon,  Nathalie Jetté,  Dennis Dlugos,  Lauren Harte-Hargrove,  Mary Jo Pugh,  Jessica K. Smith,  Solomon L. Moshé, 
  • Pages: 528-538
  • First Published: 24 February 2020

Positive illusions determine quality of life in drug-resistant epilepsy

Sarah J. Wilson,  Genevieve Rayner,  Jessamae Pieters, 
  • Pages: 539-548
  • First Published: 27 February 2020
Open Access

New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome

Ettore Tiraboschi,  Silvia Martina,  Wietske van der Ent,  Kamil Grzyb,  Kinga Gawel,  Maria Lorena Cordero-Maldonado,  Suresh Kumar Poovathingal,  Sarah Heintz,  Somisetty Venkata Satheesh,  Jarle Brattespe,  Ju Xu,  Maximiliano Suster,  Alexander Skupin,  Camila V. Esguerra, 
  • Pages: 549-560
  • First Published: 24 February 2020

Optogenetic intervention of seizures improves spatial memory in a mouse model of chronic temporal lobe epilepsy

Hannah K. Kim,  Tilo Gschwind,  Theresa M. Nguyen,  Anh D. Bui,  Sylwia Felong,  Kristen Ampig,  David Suh,  Annie V. Ciernia,  Marcelo A. Wood,  Ivan Soltesz, 
  • Pages: 561-571
  • First Published: 18 February 2020

Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin

Shruthi H. Iyer,  Ankita Aggarwal,  Ted J. Warren,  Jodi Hallgren,  Peter W. Abel,  Timothy A. Simeone,  Kristina A. Simeone, 
  • Pages: 572-588
  • First Published: 06 February 2020

BRIEF COMMUNICATION

SUDEP among young adults in the San Diego County Medical Examiner Office

Esma Karlovich,  Orrin Devinsky,  Michael Brandsoy,  Daniel Friedman, 
  • Pages: e17-e22
  • First Published: 06 February 2020

GRAY MATTERS

Announcements

Announcements

  • Pages: 589-593
  • First Published: 20 March 2020