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ISSUE INFORMATION - COPYRIGHT
ISSUE INFORMATION - EDITORIAL BOARD
ISSUE INFORMATION - TOC
CORONARY ARTERY DISEASE
ORIGINAL STUDIES
Temporal changes in patient characteristics and outcomes in ST-segment elevation myocardial infarction 2003–2018
- Pages: 1109-1117
- First Published: 15 April 2020
EDITORIAL COMMENT
The remnant of our success
- Pages: 1118-1119
- First Published: 11 May 2021
- Mortality associated with ST-elevation myocardial infarction (STEMI) has increased despite improved door to balloon times due to increased patient complexity with more patients presenting to the catheterization lab with cardiac arrest and cardiogenic shock.
- Emphasis on multimodal treatments of STEMI patients presenting with cardiogenic shock including early percutaneous coronary intervention with circulatory support when appropriate will likely provide the best clinical outcomes.
- Future research should involve continued study of clinical outcomes in STEMI patients as use of various mechanical support increases.
ORIGINAL STUDIES
One-year outcomes of supersaturated oxygen therapy in acute anterior myocardial infarction: The IC-HOT study
- Pages: 1120-1126
- First Published: 10 July 2020
EDITORIAL COMMENT
Supersaturated oxygen therapy in acute anterior myocardial infarction: Going small is the next big thing
- Pages: 1127-1128
- First Published: 11 May 2021
- Improving myocardial salvage and reducing infarct size to optimize post-myocardial infarction sequelae of heart failure and mortality remain an important goal in the primary PCI era.
- Intra-coronary supersaturated oxygen therapy is relatively new with unknown long-term outcomes.
- The current study presents evidence of improved clinical outcomes after supersaturated oxygen therapy but is limited in size and study design necessitating further investigation before widespread adoption.
ORIGINAL STUDIES
Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock
- Pages: 1129-1138
- First Published: 30 May 2020
EDITORIAL COMMENT
Lies, damned lies, and statistics, but bleeding and acute limb ischemia are facts!
- Pages: 1139-1140
- First Published: 11 May 2021
- Bleeding and ischemic limb complications continue to plague patients with cardiogenic shock.
- These complications are iatrogenic as they are not part of the pathophysiology of cardiogenic shock syndrome and are an attractive target for quality improvement.
- Standardized care with vascular bundles may represent an important concept to reduce complications in this high-risk patient group.
ORIGINAL STUDIES
Impact of manual thrombectomy on microvascular obstruction in STEMI patients
- Pages: 1141-1148
- First Published: 11 April 2020
EDITORIAL COMMENT
The inconsistency of manual thrombectomy and the role of contemporary thrombus grading in PCI for STEMI
- Pages: 1149-1150
- First Published: 11 May 2021
- Manual thrombectomy (MT) is a negative determinant for MVO occurrence and extent in STEMI patients with a high thrombus grade.
- Integration of contemporary thrombus grading classification is essential to ensure efficacious and safe PCI.
- Aiming to reduce MVO occurrence and extent in STEMI patients indicates a role for power sourced, real mechanical thrombectomy devices as the preferred revascularization tools in heavy thrombus burden.
ORIGINAL STUDIES
Benefit of a staged in-hospital revascularization strategy in hemodynamically stable patients with ST-segment elevation myocardial infarction and multivessel disease: Analyses by risk stratification
- Pages: 1151-1159
- First Published: 22 June 2020
EDITORIAL COMMENT
GRACEfully assessing the timeline for noninfarct-related artery intervention in ST-elevation myocardial infarction patients
- Pages: 1160-1161
- First Published: 11 May 2021
- A large registry study of ST-elevation myocardial infarction (STEMI) patients with multivessel disease and without cardiogenic shock demonstrated that staged in-hospital intervention of the noninfarct-related artery was associated with a reduced risk of all-cause mortality when compared to culprit-only PCI or immediate multivessel intervention.
- A subgroup analysis stratified by the Global Registry of Acute Coronary Events (GRACE) score, showed a mortality benefit in high-risk patients (GRACE score > 140) undergoing staged in-hospital intervention of the noninfarct-related artery with a median interval between the two procedures of 5 days.
- Further large, randomized trials are needed to help clarify appropriate timing for nonculprit staged intervention in STEMI patients.
ORIGINAL STUDIES
Outcomes of retrograde chronic total occlusion percutaneous coronary intervention: A report from the OPEN-CTO registry
- Pages: 1162-1173
- First Published: 02 September 2020
EDITORIAL COMMENT
With great power comes great responsibility: When and how to use the retrograde approach to chronic total occlusion interventions
- Pages: 1174-1175
- First Published: 11 May 2021
- The retrograde approach to chronic total occlusion (CTO) percutaneous coronary intervention (PCI) is a powerful tool for successful CTO crossing, especially in complex occlusions.
- Compared with antegrade-only CTO PCI, the retrograde approach is associated with increased risk of periprocedural complications.
- The retrograde approach should be used when the anticipated benefits outweigh the potential risks and should be performed in a meticulous, systematic, and stepwise fashion to maximize the likelihood of success and minimize the risk of complications.
ORIGINAL STUDIES
Predictors and outcomes of procedural failure of percutaneous coronary intervention of a chronic total occlusion—A subanalysis of the EXPLORE trial
- Pages: 1176-1183
- First Published: 15 April 2020
EDITORIAL COMMENT
Chronic coronary total occlusions: Let's make the long story short
- Pages: 1184-1185
- First Published: 11 May 2021
- Noninfarct-related chronic total occlusions are encountered approximately in 15% of patients presenting with acute ST-elevation myocardial infarction.
- The presence of noninfarct-related chronic total occlusion portends worse mid- and long-term clinical outcomes in accordance with the “spare tire” hypothesis.
- Numerous risk scores have been developed for ascertaining procedural success for chronic total occlusion percutaneous coronary interventions.
- Complete occlusion length over 20 mm is a readily available, important factor for unsuccessful chronic total occlusion recanalization, both in stable coronary artery disease and in patients with noninfarct-related chronic total occlusion.
ORIGINAL STUDIES
Impact of body mass index on outcome and health status after chronic total occlusion percutaneous coronary intervention: Insights from the OPEN-CTO study
- Pages: 1186-1193
- First Published: 22 April 2020
EDITORIAL COMMENT
The enigma continues: Obesity in chronic total occlusion patients does not affect success or complications…but Americans are still too fat!
- Pages: 1194-1195
- First Published: 11 May 2021
- Eighty-five percent of patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in the OPEN-CTO registry were either overweight or obese.
- There is no difference in procedure success and outcomes between overweight and obese patients undergoing CTO PCI compared to normal weight.
- Overweight and obese patients derive similar health status benefits after CTO PCI.
ORIGINAL STUDIES
Modulated radiation protocol achieves marked reduction of radiation exposure for chronic total coronary occlusion intervention
- Pages: 1196-1206
- First Published: 15 July 2020
EDITORIAL COMMENT
Achieving radiation reduction by adapting to technology advances
- Pages: 1207-1208
- First Published: 11 May 2021
- This study demonstrates that the combination of image processing enhancements along with meticulous attention by operators to radiation hygiene can lead to significant and clinically meaningful reductions in radiation exposure.
- The results obtained from a single experienced chronic total occlusion (CTO) operator in two sequential time periods are a reasonable substitute for a randomized trial.
- Radiation exposure to patients and operators remains a significant hazard of CTO procedures.
- Avoiding excessive dosage removes a barrier to successful procedural completion.
CASE REPORTS
Unmasking right ventricular failure in cardiogenic shock: The importance of serial hemodynamics
- Pages: 1209-1212
- First Published: 23 January 2021
An ultra-low-profile 0.85 mm Nano Hydro balloon to treat wire-crossable balloon-uncrossable lesions: A useful tool in CTO armamentarium
- Pages: 1213-1217
- First Published: 07 February 2021
Colossal left main to right atrium fistula ligation complicated by left circumflex STEMI
- Pages: 1218-1220
- First Published: 17 October 2020
CORE CURRICULUM
The role of rivaroxaban for patients with atherosclerotic vascular disease in the modern era
- Pages: 1221-1229
- First Published: 08 July 2020
VALVULAR AND STRUCTURAL HEART DISEASES
ORIGINAL STUDIES
Initial clinical experience with VersaCross transseptal system for transcatheter mitral valve repair
- Pages: 1230-1234
- First Published: 11 November 2020
EDITORIAL COMMENT
More energy, more costs
- Page: 1235
- First Published: 11 May 2021
- Transseptal access has been widely disseminated with a relatively low complication rate.
- The VersaCross Transseptal system utilizes radiofrequency energy to facilitate transseptal access enhancing ease and efficiency of procedures.
- Rising costs of structural heart interventions may impact resource allocation for medical devices.
ORIGINAL STUDIES
Impact of cleft-like indentations on procedural outcome of percutaneous edge-to-edge mitral valve repair
- Pages: 1236-1243
- First Published: 01 October 2020
30-day patient reported outcomes can be predicted by change in left atrial pressure and not change in transmitral gradient following MitraClip
- Pages: 1244-1249
- First Published: 27 January 2021
EDITORIAL COMMENT
Should the mean left atrial pressure be the ultimate goal after TMVR?
- Pages: 1250-1251
- First Published: 11 May 2021
- Transcatheter mitral valve repair (TMVR) using Mitraclip is now the standard of care for treatment of severe symptomatic mitral regurgitation (MR) in patients who are at high-surgical risk.
- Although acute reduction in regurgitant MR volume has been the main goal of successful treatment, many other hemodynamic parameters also important for accurate assessment and confirmation of the acute procedural outcome.
- Acute reduction of the mean left atrial pressure (MLAP) following TMVR seems to be well correlated with successful clinical outcomes at 30 days.
ORIGINAL STUDIES
Impact of atrial fibrillation on outcomes following MitraClip: A contemporary population-based analysis
- Pages: 1252-1256
- First Published: 05 October 2020
EDITORIAL COMMENT
Clipping mitral valve or atrial fibrillation? Two is better than one!
- Pages: 1257-1258
- First Published: 11 May 2021
- Patients with atrial fibrillation (AF) undergoing MitraClip experience a doubled risk of in-hospital stroke and higher 30-day mortality.
- Strategies to prevent in-hospital stroke in AF patients undergoing MitraClip may involve both pre- and intra-procedural management.
- Specific trials are needed to assess the impact of uninterrupted anticoagulation, early heparinization, and previous AF ablation on outcome following MitraClip.
ORIGINAL STUDIES
Use of MitraClip for mitral valve repair in patients with acute mitral regurgitation following acute myocardial infarction: Effect of cardiogenic shock on outcomes (IREMMI Registry)
- Pages: 1259-1267
- First Published: 18 February 2021
EDITORIAL COMMENT
Tailwind of transcatheter mitral valve repair pushes forward the treatment of acute mitral regurgitation after myocardial infarction
- Pages: 1268-1269
- First Published: 11 May 2021
- Acute mitral regurgitation after myocardial infarction is associated with high mortality and morbidity.
- Treatment with the MitraClip is associated with high procedural success and acceptable mortality whether they presented in or out of cardiogenic shock, provided initial hemodynamic stabilization was first achieved before PMVR.
- This transcatheter technique represents a valid alternative for selected patients and prospective studies are warranted to inform patient selection and periprocedural management in this acute setting.
ORIGINAL STUDIES
Dedicated plug based closure for large bore access –The MARVEL prospective registry
- Pages: 1270-1278
- First Published: 21 December 2020
EDITORIAL COMMENT
Large-bore vascular closure: Evolution not revolution for now
- Pages: 1279-1280
- First Published: 11 May 2021
- Closure technology has expanded modestly since the dawn of transcatheter aortic valve replacement (TAVR)—most improvements in outcomes have come from evolving techniques, smaller TAVR devices, better operator skills, and lower risk patients.
- The MANTA device adapts a well-established sandwiching of a resorbable anchor and collagen plug to large-bore closure.
- The choice of large-bore closure devices will remain one of the operator's preference pending a sufficiently powered randomized trial.
ORIGINAL STUDIES
12-Month outcomes of transcatheter tricuspid valve repair with the PASCAL system for severe tricuspid regurgitation
- Pages: 1281-1289
- First Published: 04 March 2021
Clinical outcomes of percutaneous debulking of tricuspid valve endocarditis in intravenous drug users
- Pages: 1290-1295
- First Published: 01 March 2021
CASE REPORT
Successful impella-assisted suction thrombectomy of right heart thrombus via the AngioVac device: Advantages, limitations, and alternatives
- Pages: 1296-1300
- First Published: 12 February 2021
HEMODYNAMIC ROUNDS
Disparate impact of severe aortic and mitral regurgitation on left ventricular dilation
- Pages: 1301-1308
- First Published: 20 January 2021
CORONARY ARTERY DISEASE
ORIGINAL STUDIES
Mid-term follow-up of balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: An experience in Latin America
- Pages: E748-E757
- First Published: 15 October 2020
Ischemic and bleeding risk after complex percutaneous coronary intervention in patients with or without high bleeding risk
- Pages: E758-E770
- First Published: 16 October 2020
Prognostic impact of collaterals in patients with a coronary chronic total occlusion: A meta-analysis of over 3,000 patients
- Pages: E771-E777
- First Published: 29 October 2020
A systematic review and meta-analysis of impact of baseline thrombocytopenia on cardiovascular outcomes and mortality in patients undergoing percutaneous coronary intervention
- Pages: E778-E788
- First Published: 24 November 2020
Cardiac and sudden death after chronic total occlusion percutaneous coronary intervention: Prognostic role of the target vessel
- Pages: E789-E800
- First Published: 17 December 2020
Adverse impact of chronic kidney disease on clinical outcomes following percutaneous coronary intervention
- Pages: E801-E809
- First Published: 16 December 2020
BASIC SCIENCE
Association between distance from the radiation source and radiation exposure: A phantom-based study
- Pages: E810-E816
- First Published: 03 September 2020
INTERVENTIONAL ROUNDS
An algorithmic approach to balloon-uncrossable coronary lesions
- Pages: E817-E825
- First Published: 31 August 2020
PEDIATRIC AND CONGENITAL HEART DISEASE
CASE REPORTS
Ductal stent endocarditis resulting in a large aortic pseudoaneurysm
- Pages: E826-E829
- First Published: 04 March 2021
Atrial flow regulator for drug-resistant pulmonary hypertension in a young child
- Pages: E830-E834
- First Published: 02 March 2021
PERIPHERAL VASCULAR DISEASE
CASE REPORTS
Morphological stabilization and regression of carotid plaque following therapy with evolocumab in a high-risk patient
- Pages: E835-E841
- First Published: 26 August 2020
Medial-to-lateral plantar loop technique for retrograde transcollateral recanalization of the lateral plantar artery in patients with type 3 plantar arch
- Pages: E842-E846
- First Published: 31 August 2020
Endovascular embolization of a lower limb arteriovenous fistula using a vascular plug deployed with a through-and-through arteriovenous access
- Pages: E847-E851
- First Published: 02 October 2020
Feasibility of the novel proximal superficial femoral artery puncture technique to recanalize chronic total occlusions
- Pages: E852-E856
- First Published: 05 October 2020
VALVULAR AND STRUCTURAL HEART DISEASES
ORIGINAL STUDIES
Association of baseline kidney disease with outcomes of transcatheter mitral valve repair by MitraClip
- Pages: E857-E867
- First Published: 23 July 2020
Acute kidney injury after MitraClip implantation in patients with severe mitral regurgitation
- Pages: E868-E874
- First Published: 31 August 2020
Transcatheter aortic valve replacement with Evolut R versus Sapien 3 in Japanese patients with a small aortic annulus: The OCEAN-TAVI registry
- Pages: E875-E886
- First Published: 14 September 2020
CASE REPORTS
Transcatheter mitral valve thrombosis: A case report and literature review
- Pages: E887-E892
- First Published: 11 November 2020
Computer-assisted valve in valve in a deteriorated Mosaic valve using a library of bioprostheses
- Pages: E893-E896
- First Published: 19 November 2020
Non-coaptation of an implanted caval valve leaflets for severe tricuspid regurgitation: Rethinking the concept of “Eustachian ridge?”
- Pages: E897-E899
- First Published: 25 January 2021