• Issue

    Liver International: Volume 43, Issue 4

    745-949
    April 2023
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ISSUE INFORMATION

Free Access

Issue Information

  • Pages: 745-749
  • First Published: 17 March 2023

REVIEWS & META-ANALYSES

Open Access

Diagnosis and management of hepatic encephalopathy: The French recommendations

Dominique Thabut,  Charlotte Bouzbib,  Lucy Meunier,  Manon Haas,  Nicolas Weiss,  Alexandre Louvet,  Francois Imbert-Bismut,  Fanny Mochel,  Yann Nadjar,  Antoine Santiago,  Thierry Thevenot,  Véronique Duhalde,  Frédéric Oberti,  Claire Francoz,  Audrey Coilly,  Marie-Noelle Hilleret,  Pascal Lebray,  Amélie Liou-Schischmanoff,  Louise Barbier,  Christophe Duvoux,  Georges-Philippe Pageaux,  Michael Bismuth,  Damien Galanaud,  Thomas De Broucker,  Jean-François Cadranel,  Vincent Leroy,  Vincent Di Martino,  Dominique Larrey,  Christophe Camus,  Olivier Scatton,  Victor De Ledinghen,  Ariane Mallat,  Marika Rudler,  Christophe Bureau,  for the Association Française pour l'Etude du Foie (AFEF) group of experts of HE recommendations , 
  • Pages: 750-762
  • First Published: 10 January 2023

Extra-hepatic morbidity and mortality in alcohol-related liver disease: Systematic review and meta-analysis

Mark D. Theodoreson,  Guruprasad P. Aithal,  Michael Allison,  Mayur Brahmania,  Ewan Forrest,  Hannes Hagström,  Stine Johansen,  Aleksander Krag,  Alisa Likhitsup,  Steven Masson,  Anne McCune,  Neil Rajoriya,  Maja Thiele,  Ian A. Rowe,  Richard Parker, 
  • Pages: 763-772
  • First Published: 24 January 2023

LIVER DISEASE AND PUBLIC HEALTH

Open Access

Viral hepatitis elimination challenges in low- and middle-income countries—Uzbekistan Hepatitis Elimination Program (UHEP)

Erkin Musabaev,  Chris Estes,  Shakhlo Sadirova,  Shokhista Bakieva,  Krestina Brigida,  Rick Dunn,  Shyamasundaran Kottilil,  Poonam Mathur,  Ameer Abutaleb,  Kathryn Razavi-Shearer,  Tim Anstiss,  Bakhodir Yusupaliev,  Homie Razavi, 
  • Pages: 773-784
  • First Published: 06 January 2023

Open Access

Confirmation of guideline-defined hepatitis C screening strategies within the ‘Check-Up35+’ examination in the primary care setting

David Petroff,  Ingmar Wolffram,  Olaf Bätz,  Katrin Jedrysiak,  Jan Kramer,  Thomas Berg,  Johannes Wiegand, 
  • Pages: 785-793
  • First Published: 09 January 2023

VIRAL HEPATITIS

Open Access

Insertions and deletions in the hypervariable region of the hepatitis E virus genome in individuals with acute and chronic infection

Paula Biedermann,  Patrycja Klink,  Maximilian K. Nocke,  Christian-Patrick Papp,  Dominik Harms,  Marianne Kebelmann,  Andrea Thürmer,  Mira Choi,  Britta Altmann,  Daniel Todt,  Jörg Hofmann,  Claus-Thomas Bock, 
  • Pages: 794-804
  • First Published: 08 January 2023
Open Access

Impact of direct-acting antiviral treatment on health utility in patients with chronic hepatitis C in hospital and community settings

William W. L. Wong,  Josephine Wong,  Karen E. Bremner,  Yasmin Saeed,  Kate Mason,  Arcturus Phoon,  Valérie Martel-Laferrière,  Julie Bruneau,  Jordan J. Feld,  Zeny Feng,  Elizabeth Baguley,  Samuel S. Lee,  Jeff Powis,  Murray D. Krahn, 
  • Pages: 805-818
  • First Published: 06 January 2023
Open Access

Hepatitis delta infection among persons living with HIV in Europe

Charles Béguelin,  Andrew Atkinson,  Anders Boyd,  Karolin Falconer,  Nikolai Kirkby,  Franziska Suter-Riniker,  Huldrych F. Günthard,  Jürgen K. Rockstroh,  Amanda Mocroft,  Andri Rauch,  Lars Peters,  Gilles Wandeler,  for EuroSIDA and SHCS , 
  • Pages: 819-828
  • First Published: 10 January 2023

METABOLIC & TOXIC LIVER DISEASES

Causal effect of lower birthweight on non-alcoholic fatty liver disease and mediating roles of insulin resistance and metabolites

Lijie Kong,  Chaojie Ye,  Yiying Wang,  Jie Zheng,  Zhiyun Zhao,  Mian Li,  Yu Xu,  Jieli Lu,  Yuhong Chen,  Min Xu,  Weiqing Wang,  Guang Ning,  Yufang Bi,  Tiange Wang, 
  • Pages: 829-839
  • First Published: 31 January 2023

PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis

Shiuan Tien,  Haoxiong Zhou,  Qi Zhou,  Huiling Liu,  Bin Wu,  Yunwei Guo, 
  • Pages: 840-854
  • First Published: 03 February 2023

GUT-LIVER AXIS, IMMUNOLOGY, IMMUNE MEDIATED AND CHOLESTATIC DISEASES

Open Access

Importance of complete response for outcomes of pregnancy in patients with autoimmune hepatitis

Susan E. Fischer,  Elsemieke S. de Vries,  Maarten E. Tushuizen,  Ynto S. de Boer,  Adriaan J. P. van der Meer,  Robert A. de Man,  Johannes T. Brouwer,  Johan P. Kuyvenhoven,  Michael Klemt-Kropp,  Tom J. G. Gevers,  Eric T. T. L. Tjwa,  Edith M. M. Kuiper,  Marc A. M. T. Verhagen,  Philip W. Friederich,  Bart van Hoek, 
  • Pages: 855-864
  • First Published: 03 January 2023

Ampicillin exacerbates acetaminophen-induced acute liver injury by inducing intestinal microbiota imbalance and butyrate reduction

Zhan-Ming Li,  Chao-Yue Kong,  Yu-Qin Mao,  Jia-Ting Huang,  Hui-Ling Chen,  Bing Han,  Li-Shun Wang, 
  • Pages: 865-877
  • First Published: 10 January 2023

GENETICS AND RARE LIVER DISEASES

Open Access

Increase of liver stiffness and altered bile acid metabolism after triple CFTR modulator initiation in children and young adults with cystic fibrosis

Alexander Schnell,  Jörg Jüngert,  Daniel Klett,  Hannah Hober,  Natalie Kaiser,  Renate Ruppel,  Annika Geppert,  Christina Tremel,  Julia Sobel,  Erika Plattner,  Sabina Schmitt-Grohé,  Sabine Zirlik,  Deike Strobel,  Markus F. Neurath,  Ferdinand Knieling,  Manfred Rauh,  Joachim Woelfle,  André Hoerning,  Adrian P. Regensburger, 
  • Pages: 878-887
  • First Published: 16 February 2023

CIRRHOSIS, LIVER FAILURE AND TRANSPLANTATION

Serum concentration of taurochenodeoxycholic acid predicts clinically significant portal hypertension

Kateřina Žížalová,  Barbora Nováková,  Marek Vecka,  Jaromír Petrtýl,  Věra Lánská,  Květa Pelinková,  Václav Šmíd,  Radan Brůha,  Libor Vítek,  Martin Leníček, 
  • Pages: 888-895
  • First Published: 21 November 2022
Open Access

Pathological neutrophil migration predicts adverse outcomes in hospitalized patients with liver cirrhosis

Mona-May Langer,  Stefanie Sichelschmidt,  Alina Bauschen,  Lea Bornemann,  Sabrina Guckenbiehl,  Matthias Gunzer,  Christian M. Lange, 
  • Pages: 896-905
  • First Published: 28 November 2022
Open Access

Liver transplantation for autoimmune hepatitis: Pre-transplant does not predict the early post-transplant outcome

Yasmina Chouik,  Claire Francoz,  Eleonora De Martin,  Olivier Guillaud,  Armand Abergel,  Mario Altieri,  Louise Barbier,  Camille Besch,  Olivier Chazouillères,  Filomena Conti,  Christophe Corpechot,  Sébastien Dharancy,  François Durand,  Christophe Duvoux,  Jean Gugenheim,  Jean Hardwigsen,  Marie-Noëlle Hilleret,  Pauline Houssel-Debry,  Nassim Kamar,  Anne Minello,  Martine Neau-Cransac,  Georges-Philippe Pageaux,  Sylvie Radenne,  Olivier Roux,  Faouzi Saliba,  Didier Samuel,  Claire Vanlemmens,  Marie-Lorraine Woehl-Jaegle,  Vincent Leroy,  Jean-Charles Duclos-Vallée,  Jérôme Dumortier, 
  • Pages: 906-916
  • First Published: 28 December 2022

LIVER CANCER

Open Access

Delivery of biannual ultrasound surveillance for individuals with cirrhosis and cured hepatitis C in the UK

Victoria Hamill,  Will Gelson,  Douglas MacDonald,  Paul Richardson,  Stephen D. Ryder,  Mark Aldersley,  Stuart McPherson,  Sumita Verma,  Rohini Sharma,  Sharon Hutchinson,  Jennifer Benselin,  Eleanor Barnes,  Indra Neil Guha,  William L. Irving,  Hamish Innes, 
  • Pages: 917-927
  • First Published: 28 January 2023

Discovery of canine drug toceranib phosphate as a repurposed agent against human hepatocellular carcinoma

Ling Qiao,  Siyuan Qin,  Ningna Weng,  Bowen Li,  Maochao Luo,  Zhe Zhang,  Li Zhou,  Dong Wang,  Canhua Huang, 
  • Pages: 928-944
  • First Published: 12 February 2023
Discovery of canine drug toceranib phosphate as a repurposed agent against human hepatocellular carcinoma

The mechanism underlying the therapeutic efficacy of TOC combined with autophagy inhibition against human HCC. TOC can directly induce apoptosis in HCC cells, and promote CYR61-mediated inhibition of the Akt/mTOR pathway, thereby triggering cytoprotective autophagy. Therefore, TOC combined with autophagy inhibitor CQ or 3-MA could enhance its anti-HCC effect.

LETTERS TO THE EDITOR

2022 open day in the University of Milan: An opportunity for HCV screening

Giovanni Aldinio,  Roberta D'Ambrosio,  Pier M. Perrone,  Silvana Castaldi, 
  • Pages: 945-946
  • First Published: 30 January 2023

Anti-HBc level predicting virological relapse after stopping nucleos(t)ide analogue in chronic hepatitis B

Chiuan-Bo Huang,  Tung-Hung Su,  Jia-Horng Kao, 
  • Pages: 947-948
  • First Published: 02 February 2023

Reply to the letter “Anti-HBc level predicting virological relapse after stopping nucleos(t)ide analogue in chronic hepatitis B”

Valerie Ohlendorf,  Benjamin Maasoumy, 
  • Page: 949
  • First Published: 24 February 2023