• Issue

    British Journal of Haematology: Volume 194, Issue 1

    3-217, e48-e58
    July 2021
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Issue Information

Free Access

Issue Information

  • Pages: 3-5
  • First Published: 29 June 2021

Images

Extramedullary pericardial haematopoiesis as a presenting feature of chronic myeloid leukaemia

Louisa Shackleton,  Julie McCarthy,  Vitaliy Mykytiv, 
  • Page: 7
  • First Published: 22 February 2021

Characteristic vacuolisation of granulocytic and erythroid precursors associated with VEXAS syndrome

Jean-Baptiste Rieu,  Ali El Kassir,  Laetitia Largeaud,  Jeremie Dion,  Thibault Comont,  Veronique Mansat-De Mas, 
  • Page: 8
  • First Published: 02 March 2021

Commentaries

Free Access

Searching for a home: phosphoinositide 3-kinase inhibitors for chronic lymphocytic leukaemia in modern clinical practice

Lindsey E. Roeker,  Meghan C. Thompson,  Anthony R. Mato, 
  • Pages: 9-10
  • First Published: 15 June 2021
Free Access

Building a better mousetrap for accurate and sensitive polymerase chain reaction

Jerry Radich, 
  • Pages: 11-13
  • First Published: 10 June 2021

Reviews

Cord blood beyond transplantation: can we use the experience to advance all cell therapies?

Andromachi Scaradavou, 
  • Pages: 14-27
  • First Published: 02 February 2021
Open Access

Current and emerging therapeutic approaches for T-cell acute lymphoblastic leukaemia

Rachael Pocock,  Nadine Farah,  Simon E. Richardson,  Marc R. Mansour, 
  • Pages: 28-43
  • First Published: 03 May 2021

COVID-19

Alpha-defensins: risk factor for thrombosis in COVID-19 infection

Suhair Abdeen,  Khalil Bdeir,  Rami Abu-Fanne,  Emad Maraga,  Mohamed Higazi,  Nigar Khurram,  Michael Feldman,  Charuhas Deshpande,  Leslie A. Litzky,  Samuel N. Heyman,  Kathleen T. Montone,  Douglas B. Cines,  Abd Al-Roof Higazi, 
  • Pages: 44-52
  • First Published: 30 May 2021

Haematological malignancy - Clinical

Open Access

Assessment of droplet digital polymerase chain reaction for measuring BCR-ABL1 in chronic myeloid leukaemia in an international interlaboratory study

Stuart Scott,  Ashley Cartwright,  Sebastian Francis,  Liam Whitby,  A. Pia Sanzone,  André Mulder,  Sara Galimberti,  Stephanie Dulucq,  Carole Mauté,  Calogero Lauricella,  Matthew Salmon,  Susan Rose,  Josh Willoughby,  Nancy Boeckx,  Niels Pallisgaard,  Jacqueline Maier,  Elisabeth O. Leibundgut,  Hana Zizkova,  Liuh Ling Goh,  Chinh Duong,  Wing F. Tang,  Edmond Ma,  Yogesh Shivakumar,  Lan Beppu,  Prasanthi Bhagavatula,  Andrew Chantry, 
  • Pages: 53-60
  • First Published: 10 June 2021

Clinical and molecular characteristics and treatment patterns of adolescent and young adult patients with chronic lymphocytic leukaemia

Hua-Jay J. Cherng,  Nadya Jammal,  Shilpa Paul,  Xuemei Wang,  Koji Sasaki,  Philip Thompson,  Jan Burger,  Alessandra Ferrajoli,  Zeev Estrov,  Susan O’Brien,  Michael Keating,  William G. Wierda,  Nitin Jain, 
  • Pages: 61-68
  • First Published: 10 May 2021
Open Access

A retrospective observational study to evaluate the clinical outcomes and routine management of patients with chronic lymphocytic leukaemia treated with idelalisib and rituximab in the UK and Ireland (RETRO-idel)

Toby A. Eyre,  Gavin Preston,  Huseini Kagdi,  Amin Islam,  Toby Nicholson,  Harry W. Smith,  Adam P. Cursley,  Heribert Ramroth,  Guan Xing,  Lin Gu,  Nishanthan Rajakumaraswamy,  Christopher Fegan, 
  • Pages: 69-77
  • First Published: 14 June 2021

Short report

Open Access

The current role of interferon in hairy cell leukaemia: clinical and molecular aspects

Giovanni M. Assanto,  Costantino Riemma,  Francesco Malaspina,  Salvatore Perrone,  Maria L. De Luca,  Alessandra Pucciarini,  Giorgia Annechini,  Gianna M. D'Elia,  Maurizio Martelli,  Robin Foà,  Enrico Tiacci,  Alessandro Pulsoni, 
  • Pages: 78-82
  • First Published: 01 May 2021

Comparison of immunohistochemistry and gene expression profiling subtyping for diffuse large B-cell lymphoma in the phase III clinical trial of R-CHOP ± ibrutinib

Sriram Balasubramanian,  Songbai Wang,  Christopher Major,  Brendan Hodkinson,  Michael Schaffer,  Laurie H. Sehn,  Peter Johnson,  Pier Luigi Zinzani,  Jodi Carey,  S. Martin Shreeve,  Steven Sun,  John Gerecitano,  Jessica Vermeulen,  Louis M. Staudt,  Wyndham Wilson, 
  • Pages: 83-91
  • First Published: 03 May 2021

Efficacy and safety of intravitreal methotrexate for vitreo-retinal lymphoma – 20 years of experience

Zohar Habot-Wilner,  Shahar Frenkel,  Jacob Pe’er, 
  • Pages: 92-100
  • First Published: 26 April 2021

Outcomes of methotrexate-associated lymphoproliferative disorders in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs

Takuya Harada,  Hiromi Iwasaki,  Tsuyoshi Muta,  Shingo Urata,  Aiko Sakamoto,  Kentaro Kohno,  Ken Takase,  Tomoya Miyamura,  Takuya Sawabe,  Hideki Asaoku,  Kensuke Oryoji,  Tomoaki Fujisaki,  Yasuo Mori,  Goichi Yoshimoto,  Masahiro Ayano,  Hiroki Mitoma,  Toshihiro Miyamoto,  Hiroaki Niiro,  Hidetaka Yamamoto,  Yumi Oshiro,  Hiroaki Miyoshi,  Koichi Ohshima,  Morishige Takeshita,  Koichi Akashi,  Koji Kato, 
  • Pages: 101-110
  • First Published: 06 April 2021

A prognostic immune risk score for diffuse large B-cell lymphoma

Shu-Yun Ma,  Xiao-Peng Tian,  Jun Cai,  Ning Su,  Yu Fang,  Yu-Chen Zhang,  Jin-Ni Wang,  Robert Peter Gale,  Qing-Qing Cai, 
  • Pages: 111-119
  • First Published: 03 May 2021
Open Access

Subgroup analysis of ICARIA-MM study in relapsed/refractory multiple myeloma patients with high-risk cytogenetics

Simon J. Harrison,  Aurore Perrot,  Adrian Alegre,  David Simpson,  Ming Chung Wang,  Andrew Spencer,  Sosana Delimpasi,  Cyrille Hulin,  Kazutaka Sunami,  Thierry Facon,  Philip Vlummens,  Kwee Yong,  Frank Campana,  Marlène Inchauspé,  Sandrine Macé,  Marie-Laure Risse,  Helgi van de Velde,  Paul Richardson, 
  • Pages: 120-131
  • First Published: 25 May 2021

Health-related quality of life in patients with relapsed or refractory multiple myeloma: treatment with daratumumab, lenalidomide, and dexamethasone in the phase 3 POLLUX trial

Torben Plesner,  Meletios A. Dimopoulos,  Albert Oriol,  Jesus San-Miguel,  Nizar J. Bahlis,  Neil Rabin,  Kenshi Suzuki,  Sung-Soo Yoon,  Dina Ben-Yehuda,  Gordon Cook,  Hartmut Goldschmidt,  Sebastian Grosicki,  Xiang Qin,  John Fastenau,  Wendy Garvin,  Robin Carson,  Thomas Renaud,  Katharine S. Gries, 
  • Pages: 132-139
  • First Published: 06 April 2021

Short report

High risk of relapse with intermediate dose cytarabine for consolidation in young favourable-risk acute myeloid leukaemia patients following induction with 7+3: a retrospective multicentre analysis and critical review of the literature

Bhaskar C. Kolla,  Nurul A. A. Halim,  Qing Cao,  Zohar Sachs,  Erica Warlick,  Daniel Weisdorf,  Aloysius Y. L. Ho,  Wong G. Chuan,  Zhentang Lao,  Fiona He, 
  • Pages: 140-144
  • First Published: 11 April 2021

Transplantation

Incidence and impact of community respiratory viral infections in post-transplant cyclophosphamide-based graft-versus-host disease prophylaxis and haploidentical stem cell transplantation

Carolyn M. Mulroney,  Muhammad Bilal Abid,  Asad Bashey,  Roy F. Chemaly,  Stefan O. Ciurea,  Min Chen,  Christopher E. Dandoy,  Miguel A. Diaz Perez,  Brian D. Friend,  Ephraim Fuchs,  Siddhartha Ganguly,  Scott R. Goldsmith,  Christopher G. Kanakry,  Soyoung Kim,  Krishna V. Komanduri,  Maxwell M. Krem,  Hillard M. Lazarus,  Per Ljungman,  Richard Maziarz,  Taiga Nishihori,  Sagar S. Patel,  Miguel-Angel Perales,  Rizwan Romee,  Anurag K. Singh,  John Reid Wingard,  Jean Yared,  Marcie Riches,  Randy Taplitz, 
  • Pages: 145-157
  • First Published: 14 June 2021

Non-transplantable cord blood units as a source for adoptive immunotherapy of leukaemia and a paradigm of circular economy in medicine

Kiriakos Koukoulias,  Anastasia Papadopoulou,  Anastasios Kouimtzidis,  Penelope-Georgia Papayanni,  Andri Papaloizou,  Damianos Sotiropoulos,  Minas Yiangou,  Paul Costeas,  Achilles Anagnostopoulos,  Evangelia Yannaki,  Panayotis Kaloyannidis, 
  • Pages: 158-167
  • First Published: 26 May 2021

Paediatrics

Influence of different asparaginase formulations in the prognosis of children with acute lymphocytic leukaemia in Brazil: a multicentre, retrospective controlled study

Mariana Bohns Michalowski,  Daiane Keller Cecconello,  Mecneide Mendes Lins,  Maria do Perpétuo Socorro Sampaio Carvalho,  Klerize Anecely de Souza Silva,  Lilian Cristofani,  Thais Alcantra Bonilha,  Bianca Faustini Baglioli,  Mara Albonei Dudeque Pianovski,  Ana Paula Kuczynski,  Pablo Santiago,  Ciliana Rechenmacher,  Ana Paula Alegretti,  Karla Rodrigues,  Mariana Rodrigues de Magalhães,  Liane Esteves Daudt, 
  • Pages: 168-173
  • First Published: 15 May 2021

Short report

Blinatumomab following haematopoietic stem cell transplantation – a novel approach for the treatment of acute lymphoblastic leukaemia in infants

Alexander Popov,  Veronika Fominikh,  Ekaterina Mikhailova,  Larisa Shelikhova,  Grigory Tsaur,  Yulia Abugova,  Elena Zerkalenkova,  Yulia Olshanskaya,  Dmitry Balashov,  Galina Novichkova,  Alexey Maschan,  Natalia Miakova, 
  • Pages: 174-178
  • First Published: 11 April 2021

Platelets, Haemostasis and Thrombosis

Thromboembolic risk in patients with lung cancer receiving systemic therapy

Cecelia J. Madison,  Ryan A. Melson,  Michael J. Conlin,  Kenneth R. Gundle,  Reid F. Thompson,  David C. Calverley, 
  • Pages: 179-190
  • First Published: 16 June 2021

Short report

Platelet autoantibody specificity and response to rhTPO treatment in patients with primary immune thrombocytopenia

Yafei Yu,  Yu Hou,  Yajing Zhao,  Hai Zhou,  Fangmiao Jing,  Yanfeng Liu,  Jun Peng,  Xinguang Liu,  Ming Hou, 
  • Pages: 191-194
  • First Published: 15 May 2021
Open Access

Risk of recurrent venous thromboembolism in patients with autoimmune diseases: data from the Registro Informatizado de Enfermedad TromboEmbólica (RIETE) registry

Jaime Borjas Howard,  Pablo Ruiz-Sada,  Karina de Leeuw,  Luciano López-Jiménez,  Carme Font,  Pablo Javier Marchena,  Olga Madridano,  Philippe Debourdeau,  Karina Meijer,  Manuel Monreal,  the Registro Informatizado de Enfermedad TromboEmbólica (RIETE) Investigators , 
  • Pages: 195-199
  • First Published: 02 June 2021

Haemoglobinopathies

Open Access

SLN124, a GalNac-siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron-overload in a mouse model of β-thalassaemia

Jim Vadolas,  Garrett Z. Ng,  Kai Kysenius,  Peter J. Crouch,  Sibylle Dames,  Mona Eisermann,  Tiwaporn Nualkaew,  Shahla Vilcassim,  Ute Schaeper,  George Grigoriadis, 
  • Pages: 200-210
  • First Published: 04 May 2021

Letters to the Editor

Free Access

False-positive heparin-PF4 latex immunoturbidimetric assay due to lupus anti-coagulant interference: a case report

Hannah L. McRae,  Jozal W. Moore,  Jainulabdeen J. Ifthikharuddin,  Majed A. Refaai, 
  • Pages: 211-213
  • First Published: 20 April 2021
Free Access

The clinicopathological analysis of organising pneumonia in myelodysplastic syndrome: high frequency in der(1;7)(q10; p10)

Manabu Matsunawa,  Yasuyuki Inoue,  Kunihiro Yagihashi,  Yoshio Aida,  Akiko Uchida,  Yu Uemura,  Yusuke Saiki,  Madoka Takimoto,  Fumiaki Sano,  Ikuo Miura,  Ayako Arai, 
  • Pages: 214-217
  • First Published: 14 April 2021

Online only

Open Access

Pembrolizumab combined with carfilzomib and low-dose dexamethasone for relapsed or refractory multiple myeloma: Cohort 2 of the phase I KEYNOTE-023 study

Philippe Moreau,  Razi Ghori,  Mohammed Farooqui,  Patricia Marinello,  Jesus San Miguel, 
  • Pages: e48-e51
  • First Published: 10 June 2021
Free Access

Characterisation of Asp669Tyr Piezo1 cation channel activity in red blood cells: an unexpected phenotype

Laurent Pérès,  David Monedero Alonso,  Morgane Nudel,  Martin Figeac,  Judith Bruge,  Shéhérazade Sebda,  Véronique Picard,  Wassim El Nemer,  Claude Preudhomme,  Christian Rose,  Stéphane Egée,  Guillaume Bouyer, 
  • Pages: e51-e55
  • First Published: 11 May 2021
Free Access

The first report of allogeneic haematopoietic stem cell transplantations for bone marrow failure performed in Sri Lanka

Wasanthi Wickramasinghe,  Ruwangi Dissanayake,  Revathi Raj,  Lallindra Gooneratne, 
  • Pages: e56-e58
  • First Published: 26 April 2021