British Journal of Haematology: Vol 183, No 2

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British Journal of Haematology

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British Journal of Haematology: Volume 183, Issue 2

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Issue Information

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Editorial Comment

Diagnosis of pulmonary embolism: should we wait YEARS?

Images in Haematology

Relative potency of the thrombopoietin receptor agonists eltrombopag, avatrombopag and romiplostim in a patient with chronic immune thrombocytopenia

“Faggot” neutrophils in acute promyelocytic leukaemia with ongoing tretinoin therapy

Reviews

The use of direct oral anticoagulants in chronic kidney disease

von Willebrand factor clearance – biological mechanisms and clinical significance

Haematological Malignancy

Targeting CD38 with daratumumab is lethal to Waldenström macroglobulinaemia cells

Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes

The MCL35 gene expression proliferation assay predicts high-risk MCL patients in a Norwegian cohort of younger patients given intensive first line therapy

Short Reports

Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial)

Paediatrics

SLC2A5 overexpression in childhood philadelphia chromosome-positive acute lymphoblastic leukaemia

Pulmonary toxicity in paediatric patients with relapsed or refractory Hodgkin lymphoma receiving brentuximab vedotin

Platelets, Haemostasis and Thrombosis

Emicizumab-mediated haemostatic function in patients with haemophilia A is down-regulated by activated protein C through inactivation of activated factor V

Idiopathic pulmonary arterial hypertension – a unrecognized cause of high-shear high-flow haemostatic defects (otherwise referred to as acquired von Willebrand syndrome) in children

ACTN1 mutations lead to a benign form of platelet macrocytosis not always associated with thrombocytopenia

Red Cells and Iron

ACS in children with sickle cell anaemia in Uganda: prevalence, presentation and aetiology

Correspondence

A three-miRNA-based expression signature at diagnosis can predict occurrence of relapse in children with t(8;21) RUNX1-RUNX1T1 acute myeloid leukaemia

“Haemochromatotic” characteristics of the human BEL-7402 cell line

Understanding patterns and correlates of daily pain using the Sickle cell disease Mobile Application to Record Symptoms via Technology (SMART)

An acquired NRAS mutation contributes to neutrophilic progression in a patient with primary myelofibrosis

Distinct clinical, laboratory and molecular features of myeloproliferative neoplasm patients with splanchnic vein thrombosis

Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins

Familial acquired thrombotic thrombocytopenic purpura: immunogenetic link with HLA-DRB1*11 and DQB1*03 antigens

Autoantibodies in immune thrombocytopenia affect the physiological interaction between megakaryocytes and bone marrow extracellular matrix proteins

Intracranial vasculopathy and infarct recurrence in children with sickle cell anaemia, silent cerebral infarcts and normal transcranial Doppler velocities

Clinical significance of SH2B3 (LNK) expression in paediatric B-cell precursor acute lymphoblastic leukaemia

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Familial acquired thrombotic thrombocytopenic purpura: immunogenetic link with HLA-DRB111 and DQB103 antigens