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    Hematological Oncology: Volume 43, Issue 1

    January 2025
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ISSUE INFORMATION

Free Access

Issue Information

  • First Published: 29 November 2024

COMMENTARY

PET2-Adapted Therapy in Patients With Advanced-Stage Hodgkin Lymphoma Treated With Frontline ABVD: Searching for the Baby in the Bathwater

Antonio Pinto,  Annarosa Cuccaro,  Matteo Bonanni,  Alberto Fresa,  Rosaria De Filippi,  Gaetano Corazzelli, 
  • First Published: 29 November 2024

ORIGINAL ARTICLE

Open Access

Molecular Features of Diffuse Large B-Cell Lymphoma Associated With Primary Treatment Resistance

Allison M. Bock,  Kerstin Wenzl,  Joseph P. Novak,  Matthew E. Stokes,  Melissa A. Hopper,  Jordan E. Krull,  Abigail R. Dropik,  Vivek Sarangi,  Maria Ortiz,  Nicholas Stong,  C. Chris Huang,  Matthew J. Maurer,  Rebecca L. King,  Umar Farooq,  Yucai Wang,  Thomas E. Witzig,  Stephen M. Ansell,  Thomas M. Habermann,  James R. Cerhan,  Anita K. Gandhi,  Grzegorz Nowakowski,  Anne J. Novak, 
  • First Published: 29 November 2024
Open Access

Prognostic Role of Pretreatment Tumor Burden and Dissemination Features From 2-[18F]FDG PET/CT in Advanced Mantle Cell Lymphoma

Domenico Albano,  Nicola Bianchetti,  Anna Talin,  Francesco Dondi,  Alessandro Re,  Alessandra Tucci,  Francesco Bertagna, 
  • First Published: 29 November 2024
Open Access

Safety and Efficacy of Tinostamustine in a Subpopulation of Patients With Relapsed/Refractory Hodgkin Lymphoma From a Phase I Trial

Anna Sureda,  Antonio Pinto,  Hervé Ghesquières,  Franck Morschhauser,  Olivier Tournilhac,  Pim Mutsaers,  Josée M. Zijlstra,  Rosaria De Filippi,  Kasia Hilgier,  Nick Manamley,  Tomas Janik,  Pier Luigi Zinzani, 
  • First Published: 01 December 2024
Open Access

Clinicopathological Characteristics of Extranodal Marginal Zone Lymphoma of the Mucosa Associated Lymphoid Tissue (MALT-Lymphoma) of the Intestine: A Single Center Analysis

Oskar Steinbrecher,  Barbara Kiesewetter,  Werner Dolak,  Rosa Brand,  Ingrid Simonitsch-Klupp,  Markus Raderer, 
  • First Published: 03 December 2024

Hypogammaglobulinemia at Diagnosis is Associated With Inferior Survival and Higher Risk of Infections in Diffuse Large B Cell Lymphoma

Åsa Lindberg,  Åsa Johansson,  Fredrik Kahn,  Göran Jönsson,  Mats Jerkeman, 
  • First Published: 03 December 2024

LETTER TO THE EDITOR

Comparing Outcomes Between CPX-351 and Fludarabine-Based Induction in Secondary Acute Myeloid Leukemia in the Real-World Setting: The Prognostic Role of Measurable Residual Disease

Carola Riva,  Paola Minetto,  Maria Chies,  Chiara Vernarecci,  Nicoletta Colombo,  Sara Rosellini,  Alessia Parodi,  Elisabetta Tedone,  Enrico Carminati,  Clara Nurra,  Francesco Puglisi,  Michela Frello,  Elena Maio,  Beatrice Ferro,  Giada Zecchetti,  Giuseppina Fugazza,  Paolo Nozza,  Michele Cea,  Roberto Massimo Lemoli,  Fabio Guolo, 
  • First Published: 05 December 2024

ORIGINAL ARTICLE

Efficacy and Safety of Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin and Prednisone for Previously Untreated Diffuse Large B-Cell Lymphoma: A Real-World, Multi-Center, Retrospective Cohort Study

Peiqi Zhao,  Shu Zhao,  Chen Huang,  Yajun Li,  Jiesong Wang,  Junqing Xu,  Lanfang Li,  Zhengzi Qian,  Wei Li,  Shiyong Zhou,  Lihua Qiu,  Xianming Liu,  Ying Chen,  Yanan Jiang,  Yanbin Zheng,  Daoguang Chen,  Hui Zhou,  Yuhuan Gao,  Qingyuan Zhang,  Huilai Zhang, 
  • First Published: 06 December 2024

PERSPECTIVE

Breaking Traditions: Evaluating Single Fraction Radiation in Indolent Lymphoma

Hazim S. Ababneh,  Chirayu G. Patel, 
  • First Published: 08 December 2024

LETTER TO THE EDITOR

In Situ Tracking of TCRβ Isoforms for Detection of T Cell Clonality: Implication for Precision Diagnosis and Targeted Immunotherapy of T-Cell Neoplasms

Marie Therese Manipadam,  Andrea Marra,  Alan Ramsay,  Sugerdana Padmasri,  Adheesh Gosh,  Margarida Neves,  Chris Bailey,  Sabine Pomplun,  Paul Maciocia,  Kate Cwynarski,  Mathieu Ferrari,  Pierre Lao-Siriex,  Miguel Piris,  Brunangelo Falini,  David Linch,  Andreas Rosenwald,  Martin Pule,  Alberto Zamò,  Teresa Marafioti, 
  • First Published: 10 December 2024

Hospital Palliative Care Team Consultations in Different Subgroups of Hematologic Malignancies

Anja M. Caspers,  Anne Pralong,  Michael Hallek,  Raymond Voltz,  Steffen T. Simon,  Dennis A. Eichenauer, 
  • First Published: 10 December 2024

Ceiling Effect of International Myeloma Working Group Frailty Score in Real-World Population of Older Adults With Cancer

Carla T. Williams,  Cenk Yildirim,  Mayuri Dharne,  Maya M. Abdallah,  Jane A. Driver,  Nikhil C. Munshi,  Nathanael R. Fillmore,  Clark DuMontier, 
  • First Published: 13 December 2024

ORIGINAL ARTICLE

Open Access

Long-Term Outcomes of Reduced-Toxicity Conditioning Using 8-Gray Total Body Irradiation, Fludarabine, and Cyclophosphamide in Children, Adolescents, and Young Adults With Hematological Malignancies

Hirokazu Morokawa,  Koichi Hirabayashi,  Yu Furui,  Eri Okura,  Shoji Saito,  Yozo Nakazawa, 
  • First Published: 14 December 2024
Open Access

Combining Total Metabolic Tumor Volume With Beta-2-Microglobulin Levels Predicts Outcomes in High-Burden Follicular Lymphoma Patients

A. Zduniak,  E. Lévêque,  S. Draye-Carbonnier,  S. Becker,  D. Tonnelet,  S. Dubois,  P. Vera,  H. Tilly,  F. Jardin,  P. Decazes,  V. Camus, 
  • First Published: 16 December 2024

Post-CAR T-Cell Therapy Failure Metabolic Parameters Predict Survival and Response in Large B-Cell Lymphoma

Hazim S. Ababneh,  Matthew J. Frigault,  Andrea K. Ng,  Chirayu G. Patel, 
  • First Published: 17 December 2024

Molecular Profiling Identifies CD49d and CD79b as Predictive Markers for Acquired Acalabrutinib Resistance in Patients With Chronic Lymphocytic Leukemia

Elena Bibikova,  Sara Parsa,  Muskan Floren,  Brian Law,  Tracy Clevenger,  Jean Cheung,  Gary De Jesus,  Kathleen Burke,  Michael Gulrajani,  Kyoko Yamaguchi,  Phuong Do,  Brian Dougherty,  David Whitston,  Graham Brock,  Veerendra Munugalavadla,  Melanie M. Frigault,  Tanja N. Hartmann,  John C. Byrd,  Richard R. Furman,  Jennifer R. Brown,  Todd Covey,  Andrew Mortlock, 
  • First Published: 23 December 2024
Open Access

Different Role of PET-CT Evaluation in Newly Diagnosed Follicular Lymphoma Upon Rituximab-Based Chemotherapy and Chemo-Free Immunotherapy

Nan Wang,  Xin-Yun Huang,  Xu-Feng Jiang,  Li Wang,  Shu Cheng,  Peng-Peng Xu,  Lei Dong,  Bin-Shen Ou-Yang,  Rong-Ji Mu,  Chen Li,  Yan Zhao,  Yan Feng,  Hong-Jing Dou,  Zhong Zheng,  Wei-Li Zhao, 
  • First Published: 23 December 2024
Open Access

Baseline Tumor Burden Assessed With AI-Guided PET/CT Total Metabolic Tumor Volume (TMTV) and LDH Levels Predict Efficacy of CAR-T in Aggressive B-Cell Lymphoma

Eugenio Galli,  Andrea Guarneri,  Federica Sorà,  Marcello Viscovo,  Ilaria Pansini,  Elena Maiolo,  Eleonora Alma,  Salvatore Annunziata,  Simona Sica,  Lucia Leccisotti,  Stefan Hohaus, 
  • First Published: 23 December 2024

LETTER TO THE EDITOR

Implications of Genetic, Biological and Clinical Parameters in Patients With Richter Syndrome: A Monocentric Experience

Idanna Innocenti,  Tommaso Quaranta,  Annamaria Tomasso,  Antonio Mosca,  Giulia Benintende,  Alberto Fresa,  Luigi Maria Larocca,  Luca Stirparo,  Francesco Iadevaia,  Florenzia Vuono,  Silvia Bellesi,  Arianna Bakacs,  Dimitar Efremov,  Valter Gattei,  Diana Giannarelli,  Francesco Autore,  Luca Laurenti, 
  • First Published: 27 December 2024

Impact of C-MYC/BCL2 Double Expression on Survival Outcomes After Autologous Transplantation in Relapsed/Refractory Diffuse Large B Cell Lymphoma—A Nationwide Retrospective Analysis in Singapore

Jing Yuan Tan,  Victor Wei Teik Ling,  Lawrence Cheng Kiat Ng,  Cindy Krisnadi,  Melinda Si Yuan Tan,  Nicholas Francis Grigoropoulos,  Shin Yeu Ong,  Chandramouli Nagarajan,  Jeffrey Kim Siang Quek,  Hein Than,  Joanne Lee,  Esther Chan,  Lip Kun Tan,  William Ying Khee Hwang,  Yeow Tee Goh,  Yeh Ching Linn,  Liang Piu Koh,  Aloysius Yew Leng Ho,  Francesca Wei Inng Lim,  Michelle Limei Poon,  Yunxin Chen, 
  • First Published: 27 December 2024

One-Day Brentuximab–Bendamustine (120 mg/m2) Every 21 Days is a Feasible, Safe and Effective Treatment for Relapsed/Refractory Hodgkin Lymphoma

H. Moatti,  P. Brice,  M-C. Laroque,  R. Di Blasi,  J. Wencel,  T. Delory,  I. Madelaine-Chambrin,  C. Schmidt-Hieber,  O. Ravdan,  C. Thieblemont,  L. Renaud, 
  • First Published: 28 December 2024

Childhood ALL and Asparaginase Intensification: Are We at the Brink?

Shyam Srinivasan, 
  • First Published: 02 January 2025

ORIGINAL ARTICLE

Lifetime Treatment Trajectories of Mantle Cell Lymphoma: Simulation Based Analysis of 20 Years of Real-World Data

Minna Harmanen,  Mika Hujo,  Reijo Sund,  Marc Sorigue,  Madiha Khan,  Roosa Prusila,  Tuula Klaavuniemi,  Esa Kari,  Esa Jantunen,  Kaisa Sunela,  Aino Rajamäki,  Erika Alanne,  Hanne Kuitunen,  Juan-Manuel Sancho,  Arja Jukkola,  Aino Rönkä,  Outi Kuittinen, 
  • First Published: 08 January 2025

LETTER TO THE EDITOR

The Role of 24-Month Progression-Free Survival (PFS24) in the Long-Term Evaluation of Patients With Diffuse Large B Cell Lymphoma (DLBCL): A Real-World Single Center Study

Pinelopi Vryttia,  Anthi Bouchla,  Christina Apostolopoulou,  Artemis Zorba,  Thomas Thomopoulos,  Ioulia Markaki,  Periklis G. Foukas,  Vasiliki Pappa,  Sotirios G. Papageorgiou, 
  • First Published: 09 January 2025

ORIGINAL ARTICLE

Clinical Impact of Osteolytic Bone Lesions in POEMS Syndrome: A Single-Center Experience of 114 Patients

Tatsuzo Mishina,  Chikako Ohwada,  Tomoki Suichi,  Shinichiro Matsui,  Arata Ishii,  Koji Takaishi,  Nagisa Oshima-Hasegawa,  Shokichi Tsukamoto,  Yusuke Takeda,  Sonoko Misawa,  Naoya Mimura,  Satoshi Kuwabara,  Chiaki Nakaseko,  Emiko Sakaida, 
  • First Published: 11 January 2025
Open Access

MicroRNA Profiling of Bone Marrow Plasma Extracellular Vesicles in Multiple Myeloma, Extramedullary Disease, and Plasma Cell Leukemia

Jana Gregorova,  Monika Vlachova,  Petra Vychytilova-Faltejskova,  Adela Dostalova,  Tereza Ruzickova,  Marek Vecera,  Lenka Radova,  Vendula Pospichalova,  Stanislava Sladecek,  Martina Hyzdalova,  Jana Kotaskova,  Marie Jarosova,  Josef Masek,  Klara Benesova,  Jiri Jarkovsky,  Lucie Rihova,  Renata Bezdekova,  Martina Almasi,  Ivanna Boichuk,  Martin Stork,  Ludek Pour,  Sabina Sevcikova, 
  • First Published: 13 January 2025

LETTER TO THE EDITOR

Open Access

Acalabrutinib in High-Risk Chronic Lymphocytic Leukaemia Naïve Patients: An Italian Multicenter Retrospective Observational Real-Life Experience

Idanna Innocenti,  Annamaria Tomasso,  Diana Giannarelli,  Lydia Scarfò,  Roberta Murru,  Andrea Visentin,  Anna Maria Frustaci,  Francesca Morelli,  Candida Vitale,  Antonio Mosca,  Alessandro Sanna,  Giuliana Farina,  Roberta Laureana,  Massimo Gentile,  Andrea Galitzia,  Raffaella Pasquale,  Francesco Autore,  Jacopo Olivieri,  Azzurra Romeo,  Marina Deodato,  Luca Stirparo,  Andrea Corbingi,  Vanessa Innao,  Francesca Perutelli,  Francesca Martini,  Paolo Sportoletti,  Alberto Fresa,  Maria Ilaria Del Principe,  Alessandra Tedeschi,  Marta Coscia,  Paolo Ghia,  Luca Laurenti, 
  • First Published: 14 January 2025

CASE REPORT

Open Access

Successful Pregnancies During Crizotinib Therapy for Anaplastic Lymphoma Kinase Positive Lymphoma

Veronica Guglielmana,  Francesco Maria Fusi,  Valentina Giardini,  Federica Cocito,  Carlo Gambacorti-Passerini, 
  • First Published: 14 January 2025

PERSPECTIVE

Impact of Recent Translational and Therapeutic Developments on Clinical Course of BCR::ABL1-Positive and -Negative Myeloproliferative Neoplasms

Tariq I. Mughal,  John Mascarenhas,  Raajit K. Rampal,  Prithviraj Bose,  Thomas Lion,  Helen Ajufo,  Abdulraheem Yacoub,  Soheil Meshinchi,  Lucia Masarova,  Ruben Mesa,  Catriona Jamieson,  Tiziano Barbui,  Giuseppe Saglio,  Richard A. Van Etten, 
  • First Published: 18 January 2025

ORIGINAL ARTICLE

Comprehensive Characterization of Overt Myelofibrosis in an Asian Cohort: Phenotype, Mutation Landscape and Discordance Among Scoring Systems

Yu-Sung Chang,  Yu-Hung Wang,  Chao-Hung Wei,  Yu-Wen Chen,  Hsing-Yu Lin,  Chien-Chin Lin,  Xavier Cheng-Hong Tsai,  Chang-Tsu Yuan,  Feng-Ming Tien,  Yun-Chu Lin,  Sze-Hwei Lee,  Yuan-Yeh Kuo,  Ming-Kai Chuang,  Bor-Sheng Ko,  Ming Yao,  Hwei-Fang Tien,  Wen-Chien Chou,  Hsin-An Hou, 
  • First Published: 24 January 2025

CORRECTION

Free Access

Correction to Elotuzumab Plus Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma: Extended Follow-Up of a Multicenter, Retrospective Real-World Experience With 321 Cases Outside of Controlled Clinical Trials

  • First Published: 23 January 2025