Hanseniaspora uvarum consistently dominates spontaneous grape juice fermentations, but the factors driving its prevalence remain unclear. Using a mock microbial community in diverse grape juices, we found H. uvarum's rapid growth enables early dominance, negatively impacting Saccharomyces cerevisiae and fermentation performance. This physiological advantage may shape spontaneous fermentation outcomes.

Tda1p is a protein kinase in Saccharomyces cerevisiae with unknown/disputed function. Its role during the diauxic shift was investigated in three independent transcriptomics experiment. From the evidence that was consistent across the experiments, we propose that TDA1 is involved in regulation of mitochondrial translation by repressing the expression of HAP-complex subunits.