Pharmacoepidemiology and Drug Safety

The Ronald D. Mann Best Paper Award

Pharmacoepidemiology and Drug Safety presents The Ronald D. Mann Best Paper Award each year to the first author of the strongest contribution within a given volume, as determined by the Editors and a representative of the International Society for Pharmacoepidemiology (ISPE).

The Award is open to all authors. Certificates and prizes are awarded at ISPE's annual meeting. The award is named after the Founding Editor of the journal, and provided by the publisher, John Wiley & Sons Limited.

2023 (Volume 32)

First Prize:

Combining Super Learner with high-dimensional propensity score to improve confounding adjustment: A real-world application in chronic lymphocytic leukemia
Dr Dhopeshwarkar, Yang Wei, Hennessy Sean, Rhodes Joanna M, Cuker Adam, Leonard Charles

Dr Dhopeshwarkar

Yang Wei

Hennessy Sean

Rhodes Joanna M

Cuker Adam

Leonard Charles

Honourable Mentions:

Bias amplification of unobserved confounding in pharmacoepidemiological studies using indication-based sampling
Dr Ahlqvist & co-authors; Madley-Dowd Paul, Ly Amanda, Rast Jessica, Lundberg Michael, Jónsson-Bachmann Egill, Berglind Daniel, Rai Dheeraj, Magnusson Cecilia, and Lee Brian

Dopamine Agonists and Risk of Lung Cancer in Patients with Restless Legs Syndrome
Dr Yang & co-authors; with Hernandez-Con Pilar, Shults Justine and Willis Allison W

Decision and timing of safety-related labeling changes for new drugs in Japan: comparison with the United States and the European Union
Dr Fukuda & co-authors; Narukawa Mamoru

Dr Fukuda

Narukawa Mamoru

2022 (Volume 31)

First Prize

Novel methods for pregnancy drug safety surveillance in the FDA Sentinel System
Elizabeth A. Suarez, Michael Nguyen, Di Zhang, Yueqin Zhao, Danijela Stojanovic, Monica Munoz, Jane Liedtka, Abby Anderson, Wei Liu, Inna Dashevsky, David Cole, Sandra DeLuccia, Talia Menzin, Jennifer Noble, Judith C. Maro

Elizabeth A. Suarez

Judith C. Maro

Honourable Mentions

Prescribed anti-glaucoma medication consumption and road traffic crash
Li Lu, Benjamin Contrand, Cedric Schweitzer, Blandine Gadegbeku, Cécile Delcourt, Emmanuel Lagarde

Li Lu

Blandine Gadegbeku

Cécile Delcourt

Emmanuel Lagarde

Risk of myopericarditis following COVID-19 mRNA vaccination in a large integrated health system: A comparison of completeness and timeliness of two methods
Katie A. Sharff, David M. Dancoes, Jodi L. Longueil, Eric S. Johnson, Paul F. Lewis

Considerations for observational study design: Comparing the evidence of opioid use between electronic health records and insurance claims
Jessica C. Young, Nabarun Dasgupta, Til Stürmer, Virginia Pate, Michele Jonsson Funk

Jessica C. Young

Nabarun Dasgupta

Til Stürmer

Virginia Pate

Michele Jonsson Funk

Alternative analytic and matching approaches for the prevalent new-user design: A simulation study
Michael Webster-Clark, Panagiotis Mavros, Elizabeth M. Garry, Til Stürmer, Shahar Shmuel, Jessica Young, Cynthia Girman

Association between tramadol use and seizures: A nationwide case–case-time-control study
Sohee Park, Hyesung Lee, Ju Hwan Kim, Ha-Lim Jeon, Ju-Young Shin

2021 (Volume 30)

First Prize

Association between inhaled corticosteroid use and COVID-19 outcomesAnders Husby, Anton Pottegård, Anders Hviid

Honourable Mention

Statins and risk of diverticular disease: Nested case–control study
Nils Skajaa, Frederikke Schønfeldt Troelsen, Lars Pedersen, Ola Ekholm, Lisa L. Strate, Rune Erichsen, Henrik Toft Sørensen

2020 (Volume 29)

First Prize

In utero opioid exposure and risk of infections in childhood: a multinational Nordic cohort study
Milada Mahic, Sonia Hernandez-Diaz, Mollie Wood, Helle Kieler, Ingvild Odsbu, Mette Nørgaard, Buket Öztürk, Brian T. Bateman, Vidar Hjellvik, Svetlana Skurtveit, Marte Handal

Honourable Mentions

Bias in case-crossover studies of medications due to persistent use: a simulation studyKatsiaryna Bykov, Shirley V. Wang, Jesper Hallas, Anton Pottegård, Malcolm Maclure, Joshua J. Gagne

Time-related biases in pharmacoepidemiology
Samy Suissa, Sophie Dell'Aniello

The Impact of Generic Aromatase Inhibitors on Initiation, Adherence and Persistence among Women With Breast Cancer: Applying Multi-State Models to Understand the Dynamics of AdherenceAaron N. Winn, Nicole M. Fergestrom, Liliana E. Pezzin, Purushottam W. Laud, Joan M. Neuner

Outcome Misclassification: impact, usual practice in Pharmacoepidemiology database studies and an online aid to correct biased estimates of risk ratio or cumulative incidence
Gillian C. Hall, Stephan Lanes, Kaatje Bollaerts, Xiaofeng Zhou, Germano Ferreira, Rosa Gini

Gastrointestinal bleeding risk with rivaroxaban vs aspirin in atrial fibrillation: a multinational study 
Laura Fanning, Ian C. K. Wong, Xue Li, Esther W. Chan, Pajaree Mongkhon, Kenneth K. C. Man, Li Wei, Wai K. Leung, Peteris Darzins, J. Simon Bell, Jenni Ilomaki, Wallis C. Y. Lau

2019 (Volume 28)

First Prize

Antidepressant use during pregnancy and risk of congenital heart defects: A case‐time‐control study
Yuelian Sun,  Lars Henning Pedersen,  Chun Sen Wu et al. (Volume 28, Issue 9)

Honourable Mentions

Identification of potential drug name confusion errors in the Sentinel System

Noelle M. Cocoros,  Kevin Haynes,  Qoua Her et al. (Volume 28 Issue 10)

An empirical assessment of immeasurable time bias in the setting of nested case-control studies: statins and all-cause mortality among patients with heart failure

In‐Sun Oh,  Kristian B. Filion,  Han Eol Jeong,  Ju‐Young Shin (Volume 28 Issue 10)

Causal Inference for Evaluating Prescription Opioid Abuse Using Trend-in-Trend Design

Nabarun Dasgupta, John Schwarz, Sean Hennessy, Askhan Ertefaie, Richard C. Dart (Volume 28 Issue 5)

The Devil’s in the Details: Reports on Reproducibility in Pharmacoepidemiologic Studies

Andrew B. Petrone,  April DuCott,  Joshua J. Gagne,  Sengwee Toh,  Judith C. Maro (Volume 28 Issue 5)

2018 (Volume 27)

First Prize

Methods for addressing “innocent bystanders” when evaluating safety of concomitant vaccines
Shirley V. Wang, Abdurrahman Abdurrob, Julia Spoendlin et al. (Volume 27, Issue 4)

Honourable Mentions

Risk of acute myocardial infarction with real‐world NSAIDs depends on dose and timing of exposure
Michèle Bally, Marie‐Eve Beauchamp, Michal Abrahamowicz, Lyne Nadeau, James M. Brophy (Volume 27, Issue 1)

Comparative effectiveness and safety of antiplatelet drugs in patients with diabetes mellitus and acute coronary syndrome
Julia Spoendlin, Joshua J. Gagne, Jennifer J. Lewey et al. (Volume 27, Issue 12)

2017 (Volume 26)

First Prize

Prevalent new-user cohort designs for comparative drug effect studies by time-conditional propensity scores
S. Suissa, E.E.M. Moody, D. Dell'Aniello (Volume 26, Issue 4)

Honourable Mentions

The effect of statins on influenza‐like illness morbidity and mortality
P. Brassard, J. Wu, P. Ernst et al. (Volume 26, Issue 1)

Relative preferences in the abuse of immediate-release vs. extended-release opioids in a sample of treatment-seeking opioid abusers

T.J. Cicero, M.S Ellis, Z.A. Kasper (Volume 26, Issue 1)

The feasibility of using multiple databases to study rare outcomes: the potential effect of long-acting beta agonists with inhaled corticosteroid therapy on asthma mortality

C.B. Johannes, L.J. McQuay, K.D. Midkiff et al. (Volume 26, Issue 4)

Impact of an opioid risk reduction initiative on motor vehicle crash risk among chronic opioid therapy patients
R.N. Hansen, R.L. Walker, S.M. Shortreed et al. (Volume 46, Issue 1)

2016 (Volume 25)

First Prize
Case–control study of oral glucose-lowering drugs in combination with long-acting insulin and the risks of incident myocardial infarction and incident stroke
James S. Floyd, Kerri L. Wiggins, et al.

Honourable Mentions
Trimethoprim–sulfonamide use during the first trimester of pregnancy and the risk of congenital anomalies
Craig Hansen, Susan E. Andrade, et al.

Generic switching of warfarin and risk of excessive anticoagulation: a Danish nationwide cohort study
Maja Hellfritzsch, Jette Rathe, et al.

Dose-response relationship between sulfonylureas and major adverse cardiovascular events in elderly patients with type 2 diabetes
Ahmed S. Abdelmoneim, Dean T. Eurich, et al.

2015 (Volume 24)

Hung-Lin Chen and Fei-Yuan Hsiao.
Domperidone, cytochrome P450 3A4 isoenzyme inhibitors and ventricular arrhythmia: a nationwide case–crossover study

Honourable Mention

Joshua A. Roth, Katharine Bradley, Kenneth E. Thummel, David L. Veenstra, and Denise Boudreau.
Alcohol misuse, genetics, and major bleeding among warfarin therapy patients in a community setting

Natalie C. Momen, Jørn Olsen, Mika Gissler, Helle Kieler, Bengt Haglund and Jiong Li
Exposure to systemic antibacterial medications during pregnancy and risk of childhood cancer

2014 (Volume 23)

Jürgen Prestel, Peter Volkers, Dirk Mentzer, Helmar C. Lehmann, Hans-Peter Hartung, and Brigitte Keller-Stanislawski, for the GBS Study Group.
Risk of Guillain–Barré syndrome following pandemic influenza A(H1N1) 2009 vaccination in Germany.

Honourable Mention

Yuelian Sun, Chun Sen Wu and Jørn Olsen.
Trimethoprim use before pregnancy and risk of congenital malformation: reanalyzed using a case-crossover design and a case-time-control design.

Marsha A. Raebel, Sophia R. Newcomer, Elizabeth A. Bayliss, Denise Boudreau, Lynn DeBar, Thomas E. Elliott, Ameena T. Ahmed, Pamala A. Pawloski, David Fisher, Sengwee Toh and William Troy Donahoo
Chronic opioid use emerging after bariatric surgery.

Douglas C. McDonald and Kenneth E. Carlson.
The ecology of prescription opioid abuse in the USA: geographic variation in patients' use of multiple prescribers (“doctor shopping”).

2013 (Volume 22)

Best Article

Adriana M. Hung, Christianne L. Roumie, Robert A. Greevy, Xulei Liu, Carlos G. Grijalva, Harvey J. Murff and Marie R. Griffin
Kidney function decline in metformin versus sulfonylurea initiators: assessment of time-dependent contribution of weight, blood pressure, and glycemic control

Honourable Mention

Shahed Iqbal, John P. Barile, William W. Thompson and Frank DeStefano
Number of antigens in early childhood vaccines and neuropsychological outcomes at age 7–10 years

Carlos Iribarren, Alfred D. Round, Jonathan A. Peng, Meng Lu, Jonathan G. Zaroff, Taylor J. Holve, Amit Prasad and Paul Stang
Validation of a population-based method to assess drug-induced alterations in the QT interval: a self-controlled crossover study

Sylvie D. Price, C. D'Arcy J. Holman, Frank M. Sanfilippo and Jon D. Emery
Use of case–time–control design in pharmacovigilance applications: exploration with high-risk medications and unplanned hospital admissions in the Western Australian elderly

2011 (Volume 20) Finalists

Best Article
John Paul Leombruno, Geoffrey C Nguyen, Paul Grootendorst, David Juurlink and Tom Einarson. Hospitalization and surgical rates in patients with Crohn's disease treated with infliximab: a matched analysis
(p 838 - 848) Vol 20 Issue 8

Honourable Mention
Daren Lin, Jamie A Seabrook, Doreen M Matsui, Susan M King, Michael J Rieder, Yaron Finkelstein. Palatability, adherence and prescribing patterns of antiretroviral drugs for children with human immunodeficiency virus infection in Canada
(p 1246 - 1252) Vol 20, Issue 12

Honourable Mention
Robert L Davis, David Eastman, Heather McPhillips, Marsha A Raebel, Susan E Andrade, David Smith, Marianne Ulcickas Yood, Sascha Dublin and Richard Platt. Risks of congenital malformations and perinatal events among infants exposed to calcium channel and beta-blockers during pregnancy.
(p 138 - 145) Vol 20, Issue 2.

Honourable Mention
Henriette Thisted Horsdal, Flemming Søndergaard, Søren Paaske Johnsen, Jørgen Rungby. Antidiabetic treatments and risk of hospitalisation with Myocardial infarction: a nationwide case-control study.
(p 331-337) Vol 20, Issue 4.

2010 (Volume 19)

Winner
Wendy Klein-Schwartz, John David Sorkin and Suzanne Doyon. Impact of the voluntary withdrawal of over-the-counter cough and cold medications on pediatric ingestions reported to poison centers.
(p 819-824) Vol 19 Issue 8

Honorable Mention
Laurent Azoulay, Verena Schneider-Lindner, Sophie Dell'Aniello, Alicia Schiffrin and Samy Suissa. Combination therapy with sulfonylureas and metformin and the prevention of death in type 2 diabetes: a nested case-control study.
(p 335-342) Vol 19 Issue 4

Honorable Mention
Alain Weill, Michel Païta, Philippe Tuppin, Jean-Paul Fagot, Anke Neumann, Dominique Simon, Philippe Ricordeau, Jean-Louis Montastruc and Hubert Allemand. Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus.
(p 1256-1262) Vol 19 Issue 12

Honorable Mention
Eric S Johnson, Jessica R Weinstein, Micah L Thorp, Robert W Platt, Amanda F Petrik, Xiuhai Yang, Sharon Anderson and David H Smith. Predicting the risk of hyperkalemia in patients with chronic kidney disease starting lisinopril.
(p 266-272) Vol 19 Issue 3

2009 (Volume 18)

Winner