Natural biopolymers generated by living organisms have been widely studied and used as biomaterials for a range of biomedical functions, incorporating drug furniture and regenerative remedy. Natural biopolymers consist of polysaccharides and animal-originated proteins, which display biochemical reactions to human extracellular matrix modules over and above other biopolymers in the human body. Hence, they do not provoke adverse effects upon contact. Natural biopolymers are uniquely interactive with the cellular domain.

Currently, there are two main challenges in biomedical research: first, the relevancy of advanced remedy medicinal products in clinics, and secondly the development of in vitro models to replace animal models. The development of state-of-the-art natural biopolymers is a promising approach to address both challenges. The natural biodegradable polymeric materials are generally more favorable for the design and fabrication of healing devices because these materials are commonly used in temporary implants and tissue repairing. For tissue engineering, the material has to possess some specific properties such as biocompatibility, absorbability, bioavailability, and the required physicochemical, biological, and mechanical properties. Tissue engineering offers the possibility to help in the regeneration of tissues damaged by disease or trauma. In some cases, it helps to create new tissues and replace failing or malfunctioning organs.

The aim of this Special Issue is to bring together original research articles and review articles about the application of biopolymers in regenerative medicine. Submissions should focus on improving our knowledge of cell responses induced by natural biopolymers.

Potential topics include but are not limited to the following:

• Current and potential applications of natural biopolymers for regenerative medicine
• Sources and preparation of natural biopolymers for regenerative medicine
• Formulations of natural biopolymer for regenerative medicine
• Natural biopolymers for buccal and bony regenerative medicine
• Natural biopolymer alterations for tissue engineering