Additive Manufacturing of Biopolymers for Tissue Engineering and Regenerative Medicine: An Overview, Potential Applications, Advancements, and Trends
This article is part of Special Issue:
Dhinakaran Veeman,
M. Swapna Sai,
P. Sureshkumar,
T. Jagadeesha,
L. Natrayan,
M. Ravichandran,
Wubishet Degife Mammo,
Corresponding Author
Dhinakaran Veeman
Centre for Additive Manufacturing and Computational Mechanics, Chennai Institute of Technology, Chennai, 600069 Tamil Nadu, India citchennai.edu.in
Search for more papers by this authorM. Swapna Sai
Centre for Additive Manufacturing and Computational Mechanics, Chennai Institute of Technology, Chennai, 600069 Tamil Nadu, India citchennai.edu.in
Search for more papers by this authorP. Sureshkumar
Department of Mechanical Engineering, Ramco Institute of Technology, Rajapalayam, Virudhunagar, Tamil Nadu, India ritrjpm.ac.in
Search for more papers by this authorT. Jagadeesha
Department of Mechanical Engineering, National Institute of Technology, Calicut, India int.gov.br
Search for more papers by this authorCorresponding Author
L. Natrayan
Department of Mechanical Engineering, Saveetha School of Engineering, SIMATS, Chennai, Tamil Nadu 602105, India saveetha.com
Search for more papers by this authorM. Ravichandran
Department of Mechanical Engineering, K. Ramakrishnan College of Engineering, Tiruchirappalli, 621 112 Tamil Nadu, India ritindia.edu
Search for more papers by this authorCorresponding Author
Wubishet Degife Mammo
Mechanical Engineering Department, Wollo University, Kombolcha Institute of Technology, Kombolcha, South Wollo-208, Amhara, Ethiopia wu.edu.et
Search for more papers by this authorDhinakaran Veeman,
M. Swapna Sai,
P. Sureshkumar,
T. Jagadeesha,
L. Natrayan,
M. Ravichandran,
Wubishet Degife Mammo,
Corresponding Author
Dhinakaran Veeman
Centre for Additive Manufacturing and Computational Mechanics, Chennai Institute of Technology, Chennai, 600069 Tamil Nadu, India citchennai.edu.in
Search for more papers by this authorM. Swapna Sai
Centre for Additive Manufacturing and Computational Mechanics, Chennai Institute of Technology, Chennai, 600069 Tamil Nadu, India citchennai.edu.in
Search for more papers by this authorP. Sureshkumar
Department of Mechanical Engineering, Ramco Institute of Technology, Rajapalayam, Virudhunagar, Tamil Nadu, India ritrjpm.ac.in
Search for more papers by this authorT. Jagadeesha
Department of Mechanical Engineering, National Institute of Technology, Calicut, India int.gov.br
Search for more papers by this authorCorresponding Author
L. Natrayan
Department of Mechanical Engineering, Saveetha School of Engineering, SIMATS, Chennai, Tamil Nadu 602105, India saveetha.com
Search for more papers by this authorM. Ravichandran
Department of Mechanical Engineering, K. Ramakrishnan College of Engineering, Tiruchirappalli, 621 112 Tamil Nadu, India ritindia.edu
Search for more papers by this authorCorresponding Author
Wubishet Degife Mammo
Mechanical Engineering Department, Wollo University, Kombolcha Institute of Technology, Kombolcha, South Wollo-208, Amhara, Ethiopia wu.edu.et
Search for more papers by this authorAcademic Editor: Senthilkumar Rajagopal
Abstract
As a technique of producing fabric engineering scaffolds, three-dimensional (3D) printing has tremendous possibilities. 3D printing applications are restricted to a wide range of biomaterials in the field of regenerative medicine and tissue engineering. Due to their biocompatibility, bioactiveness, and biodegradability, biopolymers such as collagen, alginate, silk fibroin, chitosan, alginate, cellulose, and starch are used in a variety of fields, including the food, biomedical, regeneration, agriculture, packaging, and pharmaceutical industries. The benefits of producing 3D-printed scaffolds are many, including the capacity to produce complicated geometries, porosity, and multicell coculture and to take growth factors into account. In particular, the additional production of biopolymers offers new options to produce 3D structures and materials with specialised patterns and properties. In the realm of tissue engineering and regenerative medicine (TERM), important progress has been accomplished; now, several state-of-the-art techniques are used to produce porous scaffolds for organ or tissue regeneration to be suited for tissue technology. Natural biopolymeric materials are often better suited for designing and manufacturing healing equipment than temporary implants and tissue regeneration materials owing to its appropriate properties and biocompatibility. The review focuses on the additive manufacturing of biopolymers with significant changes, advancements, trends, and developments in regenerative medicine and tissue engineering with potential applications.
Conflicts of Interest
The authors declare that there are no conflicts of interest regarding the publication of this paper.
Open Research
Data Availability
The data used to support the findings of this study are included within the article. Should further data or information be required, these are available from the corresponding author upon request.
References
- 1 Bose S., Koski C., and Ashley A. V., Additive manufacturing of natural biopolymers and composites for bone tissue engineering, Materials Horizons. (2020) 7, no. 8, 2011–2027, https://doi.org/10.1039/D0MH00277A.
- 2 Kuhnt T. and Camarero-Espinosa S., Additive manufacturing of nanocellulose based scaffolds for tissue engineering: beyond a reinforcement filler, Carbohydrate Polymers. (2021) 252, article 117159, https://doi.org/10.1016/j.carbpol.2020.117159.
- 3 Kundu J., Shim J.-H., Jang J., Kim S.-W., and Cho D.-W., An additive manufacturing–based PCL–alginate–chondrocyte bioprinted scaffold for cartilage tissue engineering, Journal of Tissue Engineering and Regenerative Medicine. (2015) 9, no. 11, 1286–1297, https://doi.org/10.1002/term.1682, 2-s2.0-84946497789, 23349081.
- 4 Pina S., Oliveira J. M., and Reis R. L., Natural–based nanocomposites for bone tissue engineering and regenerative medicine: a review, Advanced Materials. (2015) 27, no. 7, 1143–1169, https://doi.org/10.1002/adma.201403354, 2-s2.0-84923000595, 25580589.
- 5 Dhariwala B., Hunt E., and Boland T., Rapid prototyping of tissue-engineering constructs, using photopolymerizable hydrogels and stereolithography, Tissue Engineering. (2004) 10, no. 9-10, 1316–1322, https://doi.org/10.1089/ten.2004.10.1316, 2-s2.0-9344233837, 15588392.
- 6 Pina S., Ribeiro V. P., Marques C. F., Maia F. R., Silva T. H., Reis R. L., and Oliveira J. M., Scaffolding strategies for tissue engineering and regenerative medicine applications, Materials. (2019) 12, no. 11, https://doi.org/10.3390/ma12111824, 2-s2.0-85067279110, 31195642.
- 7 Di Marzio N., Eglin D., Serra T., and Moroni L., Bio-fabrication: convergence of 3D bioprinting and nano-biomaterials in tissue engineering and regenerative medicine, Frontiers in Bioengineering and Biotechnology. (2020) 8, https://doi.org/10.3389/fbioe.2020.00326.
- 8
Nagesha B.,
Dhinakaran V.,
Shree M. V.,
Kumar K. M.,
Chalawadi D., and
Sathish T., Review on characterization and impacts of the lattice structure in additive manufacturing, Materials Today: Proceedings. (2020) 21, 916–919.
10.1016/j.matpr.2019.08.158 Google Scholar
- 9
Vyas C.,
Pereira R.,
Huang B.,
Liu F.,
Wang W., and
Bartolo P., Engineering the vasculature with additive manufacturing, Current Opinion in Biomedical Engineering. (2017) 2, 1–13, https://doi.org/10.1016/j.cobme.2017.05.008, 2-s2.0-85042121645.
10.1016/j.cobme.2017.05.008 Google Scholar
- 10 Li X., Cui R., Sun L., Aifantis K. E., Fan Y., Feng Q., Cui F., and Watari F., 3D-printed biopolymers for tissue engineering application, International Journal of Polymer Science. (2014) 2014, 13, 829145, https://doi.org/10.1155/2014/829145, 2-s2.0-84901049672.
- 11 Mantha S., Pillai S., Khayambashi P., Upadhyay A., Zhang Y., Tao O., Pham H. M., and Tran S. D., Smart hydrogels in tissue engineering and regenerative medicine, Materials. (2019) 12, no. 20, https://doi.org/10.3390/ma12203323, 31614735.
- 12 Lee J., Lee S.-H., Kim B. S., Cho Y.-S., and Park Y., Development and evaluation of hyaluronic acid-based hybrid bio-ink for tissue regeneration, Tissue Engineering and Regenerative Medicine. (2018) 15, no. 6, 761–769, https://doi.org/10.1007/s13770-018-0144-8, 2-s2.0-85056992784, 30603594.
- 13
Sahranavard M.,
Zamanian A.,
Ghorbani F., and
Shahrezaee M. H., A critical review on three dimensional-printed chitosan hydrogels for development of tissue engineering, Bioprinting. (2020) 17, article e00063, https://doi.org/10.1016/j.bprint.2019.e00063.
10.1016/j.bprint.2019.e00063 Google Scholar
- 14 Kim J. E., Kim S. H., and Jung Y., Current status of three-dimensional printing inks for soft tissue regeneration, Tissue Engineering and Regenerative Medicine. (2016) 13, no. 6, 636–646, https://doi.org/10.1007/s13770-016-0125-8, 2-s2.0-85006089902, 30603445.
- 15 Lynch C. R., Kondiah P. P. D., and Choonara Y. E., Advanced strategies for tissue engineering in regenerative medicine: a biofabrication and biopolymer perspective, Molecules. (2021) 26, no. 9, article 2518, https://doi.org/10.3390/molecules26092518, 33925886.
- 16 Safinsha S. and Mubarak Ali M., Composite scaffolds in tissue engineering, Materials Today: Proceedings. (2020) 24, 2318–2329.
- 17 Kashte S. and Kadam S., Advances and innovations and impediments in tissue engineering and regenerative medicine, 2019, Crimson Publishers.
- 18 Gupta S. and Bit A., 3D bioprinting in tissue engineering and regenerative medicine, Cell and Tissue Banking. (2021) 1–14.
- 19 Dzobo K., Thomford N. E., Senthebane D. A., Shipanga H., Rowe A., Dandara C., Pillay M., and Motaung K. S. C. M., Advances in regenerative medicine and tissue engineering: innovation and transformation of medicine, Stem Cells International. (2018) 2018, 24, 2495848, https://doi.org/10.1155/2018/2495848, 2-s2.0-85058972214, 30154861.
- 20 Stratton S., Manoukian O. S., Patel R., Wentworth A., Rudraiah S., and Kumbar S. G., Polymeric 3D printed structures for soft–tissue engineering, Journal of Applied Polymer Science. (2018) 135, no. 24, https://doi.org/10.1002/app.45569, 2-s2.0-85029404932, 29887640.
- 21 Tricomi B. J., Dias A. D., and Corr D. T., Stem cell bioprinting for applications in regenerative medicine, Annals of the New York Academy of Sciences. (2016) 1383, no. 1, 115–124, https://doi.org/10.1111/nyas.13266, 2-s2.0-85017212690, 27870077.
- 22 Alblawi A., Ranjani A. S., Yasmin H., Gupta S., Bit A., and Rahimi-Gorji M., Scaffold-free: a developing technique in field of tissue engineering, Computer Methods and Programs in Biomedicine. (2020) 185, https://doi.org/10.1016/j.cmpb.2019.105148.
- 23 Murphy C., Kolan K., Li W., Semon J., Day D., and Leu M., 3D bioprinting of stem cells and polymer/bioactive glass composite scaffolds for bone tissue engineering, International Journal of Bioprinting. (2017) 3, https://doi.org/10.18063/ijb.2017.01.005, 2-s2.0-85040840203.
- 24 Fonseca D. R., Sobreiro-Almeida R., Sol P. C., and Neves N. M., Development of non-orthogonal 3D-printed scaffolds to enhance their osteogenic performance, Biomaterials Science. (2018) 6, no. 6, 1569–1579, https://doi.org/10.1039/C8BM00073E, 2-s2.0-85047721649, 29708246.
- 25 Oliveira A. L., Sampaio S. C., Sousa R. A., and Reis R. L., Controlled mineralization of nature-inspired silk fibroin/hydroxyapatite hybrid bioactive scafolds for bone tissue engineering applications, Proceedings of the 20th European Conference on Biomaterials, 2006, Nantes, France.
- 26 Du Y., Liu H., Yang Q., Wang S., Wang J., Ma J., Noh I., Mikos A. G., and Zhang S., Selective laser sintering scaffold with hierarchical architecture and gradient composition for osteochondral repair in rabbits, Biomaterials. (2017) 137, 37–48, https://doi.org/10.1016/j.biomaterials.2017.05.021, 2-s2.0-85019589885, 28528301.
- 27 Dong Y. F., Liang J. N., Cui Y. H., Xu S., and Zhao N. R., Fabrication of novel bioactive hydroxyapatite-chitosan-silica hybrid scaffolds: combined the sol-gel method with 3D plotting technique, Carbohydrate Polymers. (2018) 197, 183–193, https://doi.org/10.1016/j.carbpol.2018.05.086, 2-s2.0-85048462914, 30007604.
- 28 Gao Q., Gu H., Zhao P., Zhang C., Cao M., Fu J., and He Y., Fabrication of electrospun nanofibrous scaffolds with 3D controllable geometric shapes, Materials and Design. (2018) 157, 159–169, https://doi.org/10.1016/j.matdes.2018.07.042, 2-s2.0-85050256881.
- 29 Da H., Jia S. J., Meng G. L., Cheng J. H., Zhou W., Xiong Z., Mu Y. J., and Liu J., The impact of compact layer in biphasic scaffold on osteochondral tissue engineering, PLoS One. (2013) 8, no. 1, article e54838, https://doi.org/10.1371/journal.pone.0054838, 2-s2.0-84873809308, 23382984.
- 30 Mehrpouya M., Vahabi H., Barletta M., Laheurte P., and Langlois V., Additive manufacturing of polyhydroxyalkanoates (PHAs) biopolymers: materials, printing techniques, and applications, Materials Science and Engineering: C. (2021) 127, article 112216, https://doi.org/10.1016/j.msec.2021.112216.
- 31 Chaunier L., Guessasma S., Belhabib S., Della Valle G., Lourdin D., and Leroy E., Material extrusion of plant biopolymers: opportunities & challenges for 3D printing, Additive Manufacturing. (2018) 21, 220–233, https://doi.org/10.1016/j.addma.2018.03.016, 2-s2.0-85044146666.
- 32
Velu R.,
Jayashankar D. K., and
Subburaj K., Additive processing of biopolymers for medical applications, Additive Manufacturing, 2021, Elsevier, 635–659.
10.1016/B978-0-12-818411-0.00019-7 Google Scholar
- 33 Cruz F., Fabrication of HA/PLLA composite scaffolds for bone tissue engineering using additive manufacturing technologies, Biopolymers. (2010) 11, 227–242.
- 34 Dhinakaran V., Lavanya M., Vigneswari K., Ravichandran M., and Vijayakumar M., Review on exploration of graphene in diverse applications and its future horizon, Materials Today: Proceedings. (2020) 27, 824–828.
- 35 Wu C.-S., Characterization, functionality and application of siliceous sponge spicules additive-based manufacturing biopolymer composites, Additive Manufacturing. (2018) 22, 13–20, https://doi.org/10.1016/j.addma.2018.04.034, 2-s2.0-85046171901.
- 36 Ecker J. V., Kracalik M., Hild S., and Haider A., 3D-material extrusion-printing with biopolymers: a review, Chemical and Materials Engineering. (2017) 5, no. 4, 83–96.
- 37 Chaunier L., Valle G. D., Lourdin D., Réguerre A.-L., Cochet K., and Leroy E., Viscous sintering kinetics of biopolymer filaments extruded for 3D printing, Polymer Testing. (2019) 77, article 105873, https://doi.org/10.1016/j.polymertesting.2019.04.020, 2-s2.0-85064656030.
- 38 Aslam Khan M. U., Abd Razak S. I., al Arjan W. S., Nazir S., Sahaya Anand T. J., Mehboob H., and Amin R., Recent advances in biopolymeric composite materials for tissue engineering and regenerative medicines: a review, Molecules. (2021) 26, no. 3, https://doi.org/10.3390/molecules26030619, 33504080.
- 39 Ilyas R. A. and Sapuan S. M., Biopolymers and biocomposites: chemistry and technology, Current Analytical Chemistry. (2020) 16, no. 5, 500–503, https://doi.org/10.2174/157341101605200603095311.
- 40 Sarker M. D., Naghieh S., Sharma N. K., Ning L., and Chen X., Bioprinting of vascularized tissue scaffolds: influence of biopolymer, cells, growth factors, and gene delivery, Journal of Healthcare Engineering. (2019) 2019, 20, 9156921, https://doi.org/10.1155/2019/9156921, 2-s2.0-85065791470, 31065331.
- 41 Dhinakaran V., Ajith J., Fahmidha A. F. Y., Jagadeesha T., Sathish T., and Stalin B., Wire arc additive manufacturing (WAAM) process of nickel based superalloys – a review, Materials Today: Proceedings. (2020) 21, 920–925.
- 42
Zarrintaj P.,
Vahabi H.,
Gutiérrez T. J.,
Mehrpouya M.,
Ganjali M. R., and
Saeb M. R., Nanocomposite biomaterials made by 3D printing: achievements and challenges, Handbook of Polymer Nanocomposites for Industrial Applications, 2021, Elsevier, 675–685.
10.1016/B978-0-12-821497-8.00025-3 Google Scholar
- 43 Yu C., Schimelman J., Wang P., Miller K. L., Ma X., You S., Guan J., Sun B., Zhu W., and Chen S., Photopolymerizable biomaterials and light-based 3D printing strategies for biomedical applications, Chemical Reviews. (2020) 120, no. 19, 10695–10743, https://doi.org/10.1021/acs.chemrev.9b00810, 32323975.
- 44 Oladapo B. I., Zahedi S. A., and Adeoye A. O. M., 3D printing of bone scaffolds with hybrid biomaterials, Composites Part B: Engineering. (2019) 158, 428–436, https://doi.org/10.1016/j.compositesb.2018.09.065, 2-s2.0-85054401149.
- 45 Jakus A. E., Geisendorfer N. R., Lewis P. L., and Shah R. N., 3D-printing porosity: a new approach to creating elevated porosity materials and structures, Acta Biomaterialia. (2018) 72, 94–109, https://doi.org/10.1016/j.actbio.2018.03.039, 2-s2.0-85046660998, 29601901.
- 46 Zafar M. J., Zhu D., and Zhang Z., 3D printing of bioceramics for bone tissue engineering, Materials. (2019) 12, no. 20, https://doi.org/10.3390/ma12203361, 31618857.
- 47 Tappa K. and Jammalamadaka U., Novel biomaterials used in medical 3D printing techniques, Journal of Functional Biomaterials. (2018) 9, no. 1, https://doi.org/10.3390/jfb9010017, 2-s2.0-85050987689, 29414913.
- 48 Richards D. J., Tan Y., Jia J., Yao H., and Mei Y., 3D printing for tissue engineering, Israel Journal of Chemistry. (2013) 53, no. 9–10, 805–814, 26869728.
- 49 Guvendiren M., Molde J., Soares R. M. D., and Kohn J., Designing biomaterials for 3D printing, ACS Biomaterials Science & Engineering. (2016) 2, no. 10, 1679–1693, https://doi.org/10.1021/acsbiomaterials.6b00121, 2-s2.0-84980522878, 28025653.
- 50 Chia H. N. and Benjamin M. W., Recent advances in 3D printing of biomaterials, Journal of Biological Engineering. (2015) 9, no. 1, 1–14.
- 51 Whyte D. J., Rajkhowa R., Allardyce B., and Kouzani A. Z., A review on the challenges of 3D printing of organic powders, Bioprinting. (2019) 16, article e00057.
- 52 Yan Q., Dong H., Jin S., Han J., Song B., Wei Q., and Shi Y., A review of 3D printing technology for medical applications, Engineering. (2018) 4, no. 5, 729–742.
- 53 Mondschein R. J., Kanitkar A., Williams C. B., Verbridge S. S., and Long T. E., Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds, Biomaterials. (2017) 140, 170–188, https://doi.org/10.1016/j.biomaterials.2017.06.005, 2-s2.0-85021160415, 28651145.
- 54 Poomathi N., Singh S., Prakash C., Subramanian A., Sahay R., Cinappan A., and Ramakrishna S., 3D printing in tissue engineering: a state of the art review of technologies and biomaterials, Rapid Prototyping Journal. (2020) 26, no. 7, 1313–1334, https://doi.org/10.1108/RPJ-08-2018-0217.
- 55 Kirchmajer D. M. and Iii R. G., An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing, Journal of Materials Chemistry B. (2015) 3, no. 20, 4105–4117, https://doi.org/10.1039/C5TB00393H, 2-s2.0-84929224464, 32262288.
- 56 Skardal A. and Atala A., Biomaterials for integration with 3-D bioprinting, Annals of Biomedical Engineering. (2015) 43, no. 3, 730–746, https://doi.org/10.1007/s10439-014-1207-1, 2-s2.0-84925745420, 25476164.
- 57 Seitz H., Rieder W., Irsen S., Leukers B., and Tille C., Three–dimensional printing of porous ceramic scaffolds for bone tissue engineering, Journal of Biomedical Materials Research Part B: Applied Biomaterials: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials. (2005) 74, no. 2, 782–788.
- 58 Leukers B., Gülkan H., Irsen S. H., Milz S., Tille C., Seitz H., and Schieker M., Biocompatibility of ceramic scaffolds for bone replacement made by 3D printing, Materialwissenschaft und Werkstofftechnik: Entwicklung, Fertigung, Prüfung, Eigenschaften und Anwendungen technischer Werkstoffe. (2005) 36, no. 12, 781–787, https://doi.org/10.1002/mawe.200500968, 2-s2.0-30344451667.
- 59 Dhinakaran V., Stalin B., Sai M. S., Vairamuthu J., and Marichamy S., Recent developments of graphene composites for energy storage devices, Materials Today: Proceedings. (2021) 45, 1779–1782, https://doi.org/10.1016/j.matpr.2020.08.631.
- 60 Wen Y., Xun S., Haoye M., Baichuan S., Peng C., Xuejian L., Kaihong Z., Yang X., Jiang P., and Lu S., 3D printed porous ceramic scaffolds for bone tissue engineering: a review, Biomaterials Science. (2017) 5, no. 9, 1690–1698.
- 61 Lee J.-B., Maeng W.-Y., Koh Y.-H., and Kim H.-E., Porous calcium phosphate ceramic scaffolds with tailored pore orientations and mechanical properties using lithography-based ceramic 3D printing technique, Materials. (2018) 11, no. 9, https://doi.org/10.3390/ma11091711, 2-s2.0-85053261216, 30217045.
- 62 Du X., Shengyang F., and Zhu Y., 3D printing of ceramic-based scaffolds for bone tissue engineering: an overview, Journal of Materials Chemistry B. (2018) 6, no. 27, 4397–4412, https://doi.org/10.1039/C8TB00677F, 2-s2.0-85049922481, 32254656.
- 63 Sampath U. G., Ching Y. C., Chuah C. H., Sabariah J. J., and Lin P.-C., Fabrication of porous materials from natural/synthetic biopolymers and their composites, Materials. (2016) 9, no. 12, https://doi.org/10.3390/ma9120991, 2-s2.0-85007344781, 28774113.
- 64 Hassan M., Dave K., Chandrawati R., Dehghani F., and Gomes V. G., 3D printing of biopolymer nanocomposites for tissue engineering: nanomaterials, processing and structure-function relation, European Polymer Journal. (2019) 121, https://doi.org/10.1016/j.eurpolymj.2019.109340.
- 65 Li K., Wang D., Zhao K., Song K., and Liang J., Electrohydrodynamic jet 3D printing of PCL/PVP composite scaffold for cell culture, Talanta. (2020) 211, https://doi.org/10.1016/j.talanta.2020.120750.
- 66 Balasubramanian S., Aubin-Tam M.-E., and Meyer A. S., 3D printing for the fabrication of biofilm-based functional living materials, ACS Synthetic Biology. (2019) 8, no. 7, 1564–1567, https://doi.org/10.1021/acssynbio.9b00192, 2-s2.0-85070059565, 31319670.
- 67 Pati F., Shim J.-H., Lee J.-S., and Cho D.-W., 3D printing of cell-laden constructs for heterogeneous tissue regeneration, Manufacturing Letters. (2013) 1, no. 1, 49–53, https://doi.org/10.1016/j.mfglet.2013.09.004, 2-s2.0-84892767539.
- 68 Nagarajan S., Radhakrishnan S., Kalkura S. N., Balme S., Miele P., and Bechelany M., Overview of protein–based biopolymers for biomedical application, Macromolecular Chemistry and Physics. (2019) 220, no. 14, article 1900126, https://doi.org/10.1002/macp.201900126, 2-s2.0-85066881638.
- 69 Xu W., Wang X., Sandler N., Willför S., and Chunlin X., Three-dimensional printing of wood-derived biopolymers: a review focused on biomedical applications, ACS Sustainable Chemistry & Engineering. (2018) 6, no. 5, 5663–5680, https://doi.org/10.1021/acssuschemeng.7b03924, 2-s2.0-85046813876, 30271688.
- 70 Saroia J., Wang Y., Wei Q., Zhang K., Lu T., and Zhang B., A review on biocompatibility nature of hydrogels with 3D printing techniques, tissue engineering application and its future prospective, Bio-Design and Manufacturing. (2018) 1, no. 4, 265–279, https://doi.org/10.1007/s42242-018-0029-7, 2-s2.0-85062729191.
- 71 Vozzi G., Previti A., De Rossi D., and Ahluwalia A. R. T. I., Microsyringe-based deposition of two-dimensional and three-dimensional polymer scaffolds with a well-defined geometry for application to tissue engineering, Tissue Engineering. (2002) 8, no. 6, 1089–1098, https://doi.org/10.1089/107632702320934182, 2-s2.0-0036892817, 12542954.
- 72 Yang S., Leong K.-F., Du Z., and Chua C.-K., The design of scaffolds for use in tissue engineering. Part II. Rapid prototyping techniques, Tissue Engineering. (2002) 8, no. 1, 1–11, https://doi.org/10.1089/107632702753503009, 2-s2.0-0036191695, 11886649.
- 73 Rasheed T., Bilal M., Zhao Y., Raza A., Shah S. Z. H., and Iqbal H. M. N., Physiochemical characteristics and bone/cartilage tissue engineering potentialities of protein-based macromolecules -- a review, International Journal of Biological Macromolecules. (2019) 121, 13–22, https://doi.org/10.1016/j.ijbiomac.2018.10.009, 2-s2.0-85054184265, 30291929.
- 74 Wan Y., Li X., and Wang S., Recent advances in biohybrid materials for tissue engineering and regenerative medicine, Journal of Molecular and Engineering Materials. (2016) 4, no. 1, https://doi.org/10.1142/S2251237316400013.
- 75 George A., Sanjay M. R., Srisuk R., Parameswaranpillai J., and Siengchin S., A comprehensive review on chemical properties and applications of biopolymers and their composites, International Journal of Biological Macromolecules. (2020) 154, 329–338, https://doi.org/10.1016/j.ijbiomac.2020.03.120, 32179114.
- 76 Novosel E. C., Kleinhans C., and Kluger P. J., Vascularization is the key challenge in tissue engineering, Advanced Drug Delivery Reviews. (2011) 63, no. 4-5, 300–311, https://doi.org/10.1016/j.addr.2011.03.004, 2-s2.0-79957713859, 21396416.
- 77
Chouhan D.,
Kaushik S., and
Arora D., Trends in bio-derived biomaterials in tissue engineering, Biomaterials in Tissue Engineering and Regenerative Medicine: From Basic Concepts to State of the Art Approaches, 2021, Springer, 163–213, https://doi.org/10.1007/978-981-16-0002-9_6.
10.1007/978-981-16-0002-9_6 Google Scholar
- 78 Udayakumar G. P., Muthusamy S., Selvaganesh B., Sivarajasekar N., Rambabu K., Banat F., Sivamani S., Sivakumar N., Hosseini-Bandegharaei A., and Show P. L., Biopolymers and composites: properties, characterization and their applications in food, medical and pharmaceutical industries, Journal of Environmental Chemical Engineering. (2021) 9, no. 4, article 105322, https://doi.org/10.1016/j.jece.2021.105322.
- 79 Li V. C.-F., Dunn C. K., Zhang Z., Deng Y., and Qi H. J., Direct ink write (DIW) 3D printed cellulose nanocrystal aerogel structures, Scientific Reports. (2017) 7, no. 1, 1–8.
- 80 Arkan E., Azandaryani A. H., Moradipour P., and Behbood L., Biomacromolecular based fibers in nanomedicine: a combination of drug delivery and tissue engineering, Current Pharmaceutical Biotechnology. (2017) 18, no. 11, 909–924, https://doi.org/10.2174/1389201019666180112144759, 2-s2.0-85043317414, 29332574.
- 81 Pérez-Pedroza R., Ávila-Ramírez A., Khan Z., Moretti M., and Hauser C. A. E., Supramolecular biopolymers for tissue engineering, Advances in Polymer Technology. (2021) 2021, 23, 8815006, https://doi.org/10.1155/2021/8815006.
- 82 Azizi-Lalabadi M. and Jafari S. M., Bio-nanocomposites of graphene with biopolymers; fabrication, properties, and applications, Advances in Colloid and Interface Science. (2021) 292, article 102416, https://doi.org/10.1016/j.cis.2021.102416.
- 83 Rezaei F. S., Khorshidian A., Beram F. M., Derakhshani A., Esmaeili J., and Barati A., 3D printed chitosan/polycaprolactone scaffold for lung tissue engineering: hope to be useful for COVID-19 studies, RSC Advances. (2021) 11, no. 32, 19508–19520, https://doi.org/10.1039/D1RA03410C.
- 84 Shoueir K. R., El-Desouky N., Rashad M. M., Ahmed M. K., Janowska I., and El-Kemary M., Chitosan based-nanoparticles and nanocapsules: overview, physicochemical features, applications of a nanofibrous scaffold, and bioprinting, International Journal of Biological Macromolecules. (2020) 167, 1176–1197.
- 85 Vinod A., Sanjay M. R., Suchart S., and Jyotishkumar P., Renewable and sustainable biobased materials: an assessment on biofibers, biofilms, biopolymers and biocomposites, Journal of Cleaner Production. (2020) 258, article 120978, https://doi.org/10.1016/j.jclepro.2020.120978.
- 86
Al-Ghraibah A. M.,
Al-Qudah M., and
AL-Oqla F. M., Medical implementations of biopolymers, Advanced Processing, Properties, and Applications of Starch and Other Bio-Based Polymers, 2020, Elsevier, 157–171.
10.1016/B978-0-12-819661-8.00010-X Google Scholar
- 87 Leukers B., Gülkan H., Irsen S. H., Milz S., Tille C., Schieker M., and Seitz H., Hydroxyapatite scaffolds for bone tissue engineering made by 3D printing, Journal of Materials Science: Materials in Medicine. (2005) 16, no. 12, 1121–1124, https://doi.org/10.1007/s10856-005-4716-5, 2-s2.0-29144502979, 16362210.
- 88 Cakmak A. M., Unal S., Sahin A., Oktar F. N., Sengor M., Ekren N., Gunduz O., and Kalaskar D. M., 3D printed polycaprolactone/gelatin/bacterial cellulose/hydroxyapatite composite scaffold for bone tissue engineering, Polymers. (2020) 12, no. 9, https://doi.org/10.3390/polym12091962, 32872547.
- 89
Liu C., Collagen–hydroxyapatite composite scaffolds for tissue engineering, Hydroxyapatite (HAp) for Biomedical Applications, 2015, Woodhead Publishing, 211–234.
10.1016/B978-1-78242-033-0.00010-9 Google Scholar
- 90 Mondal S. and Pal U., 3D hydroxyapatite scaffold for bone regeneration and local drug delivery applications, Journal of Drug Delivery Science and Technology. (2019) 53, https://doi.org/10.1016/j.jddst.2019.101131, 2-s2.0-85067961531.
- 91 Arslan Y. E., Arslan T. S., Derkus B., Emregul E., and Emregul K. C., Fabrication of human hair keratin/jellyfish collagen/eggshell-derived hydroxyapatite osteoinductive biocomposite scaffolds for bone tissue engineering: from waste to regenerative medicine products, Colloids and Surfaces B: Biointerfaces. (2017) 154, 160–170, https://doi.org/10.1016/j.colsurfb.2017.03.034, 2-s2.0-85015980136, 28334693.
- 92 Corcione C. E., Gervaso F., Scalera F., Montagna F., Maiullaro T., Sannino A., and Maffezzoli A., 3D printing of hydroxyapatite polymer-based composites for bone tissue engineering, Journal of Polymer Engineering. (2017) 37, no. 8, 741–746, https://doi.org/10.1515/polyeng-2016-0194, 2-s2.0-85031094101.
- 93 Moncal K. K., Heo D. N., Godzik K. P., Sosnoski D. M., Mrowczynski O. D., Rizk E., Ozbolat V., Tucker S. M., Gerhard E. M., Dey M., Lewis G. S., Yang J., and Ozbolat I. T., 3D printing of poly(ε-caprolactone)/poly(D,L-lactide-co-glycolide)/hydroxyapatite composite constructs for bone tissue engineering, Journal of Materials Research. (2018) 33, no. 14, 1972–1986, https://doi.org/10.1557/jmr.2018.111, 2-s2.0-85049298960.
- 94 Kim S.-J., Kim E. M., Yamamoto M., Park H., and Shin H., Engineering multi–cellular spheroids for tissue engineering and regenerative medicine, Advanced Healthcare Materials. (2020) 9, no. 23, article 2000608, https://doi.org/10.1002/adhm.202000608.
- 95 Datta S., Barua R., and Das J., Importance of alginate bioink for 3D bioprinting in tissue engineering and regenerative medicine, 2020, IntechOpen, London, UK.
- 96 Asadi N., Del Bakhshayesh A. R., Davaran S., and Akbarzadeh A., Common biocompatible polymeric materials for tissue engineering and regenerative medicine, Materials Chemistry and Physics. (2020) 242, https://doi.org/10.1016/j.matchemphys.2019.122528.
- 97 Smith I. O., Liu X. H., Smith L. A., and Ma P. X., Nanostructured polymer scaffolds for tissue engineering and regenerative medicine, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. (2009) 1, no. 2, 226–236.
- 98 Ifkovits J. L. and Burdick J. A., Review: photopolymerizable and degradable biomaterials for tissue engineering applications, Tissue Engineering. (2007) 13, no. 10, 2369–2385, https://doi.org/10.1089/ten.2007.0093, 2-s2.0-35348874191, 17658993.
- 99 Ramiah P., du Toit L. C., Choonara Y. E., Kondiah P. P. D., and Pillay V., Hydrogel-based bioinks for 3D bioprinting in tissue regeneration, Frontiers in Materials. (2020) 7, https://doi.org/10.3389/fmats.2020.00076.
- 100 McHale M. K., Setton L. A., and Chilkoti A., Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair, Tissue Engineering. (2005) 11, no. 11-12, 1768–1779, https://doi.org/10.1089/ten.2005.11.1768, 2-s2.0-31044449508.
- 101 He W., Yong T., Teo W. E., Ma Z., and Ramakrishna S., Fabrication and endothelialization of collagen-blended biodegradable polymer nanofibers: potential vascular graft for blood vessel tissue engineering, Tissue Engineering. (2005) 11, no. 9-10, 1574–1588, https://doi.org/10.1089/ten.2005.11.1574, 2-s2.0-27744469532, 16259611.
- 102 Nicodemus G. D. and Bryant S. J., Cell encapsulation in biodegradable hydrogels for tissue engineering applications, Tissue Engineering Part B: Reviews. (2008) 14, no. 2, 149–165, https://doi.org/10.1089/ten.teb.2007.0332, 2-s2.0-45249104205, 18498217.
- 103 Shields K. J., Beckman M. J., Bowlin G. L., and Wayne J. S., Mechanical properties and cellular proliferation of electrospun collagen type II, Tissue Engineering. (2004) 10, no. 9-10, 1510–1517, https://doi.org/10.1089/ten.2004.10.1510, 2-s2.0-9344220476, 15588410.
- 104 Magin C. M., Alge D. L., and Anseth K. S., Bio-inspired 3D microenvironments: a new dimension in tissue engineering, Biomedical Materials. (2016) 11, no. 2, article 022001, https://doi.org/10.1088/1748-6041/11/2/022001, 2-s2.0-84964515094, 26942469.
- 105 Woodfield T. B. F., Van Blitterswijk C. A., De Wijn J., Sims T. J., Hollander A. P., and Riesle J., Polymer scaffolds fabricated with pore-size gradients as a model for studying the zonal organization within tissue-engineered cartilage constructs, Tissue Engineering. (2005) 11, no. 9-10, 1297–1311, https://doi.org/10.1089/ten.2005.11.1297, 2-s2.0-27744606356, 16259586.
- 106 Kretlow J. D. and Mikos A. G., Review: mineralization of synthetic polymer scaffolds for bone tissue engineering, Tissue Engineering. (2007) 13, no. 5, 927–938, https://doi.org/10.1089/ten.2006.0394, 2-s2.0-34249889877, 17430090.
- 107 Danilevicius P., Rekštyte S., Gadonas R., Malinauskas M., Balciunas E., Jarasiene R., Baltriukiene D., Bukelskiene V., Kraniauskas A., and Sirmenis R., Micro-structured polymer scaffolds fabricated by direct laser writing for tissue engineering, Journal of Biomedical Optics. (2012) 17, no. 8, article 081405, https://doi.org/10.1117/1.JBO.17.8.081405, 2-s2.0-84866502231, 23224166.
- 108 Prasopthum A., Deng Z., Khan I. M., Yin Z., Guo B., and Yang J., Three dimensional printed degradable and conductive polymer scaffolds promote chondrogenic differentiation of chondroprogenitor cells, Biomaterials Science. (2020) 8, no. 15, 4287–4298, https://doi.org/10.1039/D0BM00621A, 32589696.
- 109
Walker J. L. and
Santoro M., Processing and production of bioresorbable polymer scaffolds for tissue engineering, Bioresorbable Polymers for Biomedical Applications, 2017, Woodhead Publishing, 181–203.
10.1016/B978-0-08-100262-9.00009-4 Google Scholar
- 110 Ma P. X. and Choi J.-W., Biodegradable polymer scaffolds with well-defined interconnected spherical pore network, Tissue Engineering. (2001) 7, no. 1, 23–33, https://doi.org/10.1089/107632701300003269, 2-s2.0-0035119040, 11224921.
- 111 Seunarine K., Gadegaard N., Tormen M., Meredith D. O., Riehle M. O., and Wilkinson C. D. W., 3D polymer scaffolds for tissue engineering, Nanomedicine. (2006) 1, no. 3, 281–296.
- 112 Jacob J., Haponiuk J. T., Thomas S., and Gopi S., Biopolymer based nanomaterials in drug delivery systems: a review, Materials Today Chemistry. (2018) 9, 43–55, https://doi.org/10.1016/j.mtchem.2018.05.002, 2-s2.0-85047423172.
- 113 Neffe A. T., Wischke C., Racheva M., and Lendlein A., Progress in biopolymer-based biomaterials and their application in controlled drug delivery, Expert Review of Medical Devices. (2013) 10, no. 6, 813–833, https://doi.org/10.1586/17434440.2013.839209, 2-s2.0-84887774308, 24195462.
- 114
Gopi S.,
Amalraj A., and
Thomas S., Effective drug delivery system of biopolymers based on nanomaterials and hydrogels-a review, Drug Designing: Open Access. (2016) 5, no. 129.
10.4172/2169-0138.1000129 Google Scholar
- 115 Chen J., Xie F., Li X., and Chen L., Ionic liquids for the preparation of biopolymer materials for drug/gene delivery: a review, Green Chemistry. (2018) 20, no. 18, 4169–4200, https://doi.org/10.1039/C8GC01120F, 2-s2.0-85053855928.
- 116 Patil G. V., Biopolymer albumin for diagnosis and in drug delivery, Drug Development Research. (2003) 58, no. 3, 219–247, https://doi.org/10.1002/ddr.10157, 2-s2.0-0038555755.
- 117 Das D. and Pal S., Modified biopolymer-dextrin based crosslinked hydrogels: application in controlled drug delivery, RSC Advances. (2015) 5, no. 32, 25014–25050, https://doi.org/10.1039/C4RA16103C, 2-s2.0-84924911483.
- 118
García M. C., Drug delivery systems based on nonimmunogenic biopolymers, Engineering of Biomaterials for Drug Delivery Systems, 2018, Woodhead Publishing, 317–344.
10.1016/B978-0-08-101750-0.00012-X Google Scholar
- 119
Grøndahl L.,
Lawrie G.,
Anitha A., and
Shejwalkar A., Applications of alginate biopolymer in drug delivery, Biointegration of Medical Implant Materials, 2020, Woodhead Publishing, 375–403.
10.1016/B978-0-08-102680-9.00014-7 Google Scholar
- 120 Rai M., Ingle A. P., Gupta I., and Brandelli A., Bioactivity of noble metal nanoparticles decorated with biopolymers and their application in drug delivery, International Journal of Pharmaceutics. (2015) 496, no. 2, 159–172.
- 121 Patra J. K., Das G., Fraceto L. F., Campos E. V. R., del Pilar Rodriguez-Torres M., Acosta-Torres L. S., Diaz-Torres L. A., Grillo R., Swamy M. K., Sharma S., Habtemariam S., and Shin H.-S., Nano based drug delivery systems: recent developments and future prospects, Journal of Nanobiotechnology. (2018) 16, no. 1, 1–33, https://doi.org/10.1186/s12951-018-0392-8, 2-s2.0-85053681127.
- 122 Okamoto M. and John B., Synthetic biopolymer nanocomposites for tissue engineering scaffolds, Progress in Polymer Science. (2013) 38, no. 10-11, 1487–1503, https://doi.org/10.1016/j.progpolymsci.2013.06.001, 2-s2.0-84885018649.
- 123 Vlierberghe V., Sandra P. D., and Schacht E., Biopolymer-based hydrogels as scaffolds for tissue engineering applications: a review, Biomacromolecules. (2011) 12, no. 5, 1387–1408, https://doi.org/10.1021/bm200083n, 2-s2.0-79955793532, 21388145.
- 124 Martino D., Alberto M. S., and Risbud M. V., Chitosan: a versatile biopolymer for orthopaedic tissue-engineering, Biomaterials. (2005) 26, no. 30, 5983–5990, https://doi.org/10.1016/j.biomaterials.2005.03.016, 2-s2.0-20444409137, 15894370.
- 125 Sahana T. G. and Rekha P. D., Biopolymers: applications in wound healing and skin tissue engineering, Molecular Biology Reports. (2018) 45, no. 6, 2857–2867, https://doi.org/10.1007/s11033-018-4296-3, 2-s2.0-85051638267, 30094529.
- 126 Pérez-Guzmán C. J. and Castro-Muñoz R., A review of zein as a potential biopolymer for tissue engineering and nanotechnological applications, Processes. (2020) 8, no. 11, https://doi.org/10.3390/pr8111376.
- 127 Khalil H. P. S. A., Jummaat F., Yahya E. B., Olaiya N. G., Adnan A. S., Abdat M., Nasir N. A. M., Halim A. S., Kumar U. S. U., Bairwan R., and Suriani A. B., A review on micro- to nanocellulose biopolymer scaffold forming for tissue engineering applications, Polymers. (2020) 12, no. 9, article 2043, https://doi.org/10.3390/polym12092043, 32911705.
- 128 Nitta S. K. and Numata K., Biopolymer-based nanoparticles for drug/gene delivery and tissue engineering, International Journal of Molecular Sciences. (2013) 14, no. 1, 1629–1654, https://doi.org/10.3390/ijms14011629, 2-s2.0-84877801388, 23344060.
- 129 Biswal T., Biopolymers for tissue engineering applications: a review, Materials Today: Proceedings. (2021) 41, 397–402, https://doi.org/10.1016/j.matpr.2020.09.628.
- 130 Ambekar R. S. and Kandasubramanian B., Progress in the advancement of porous biopolymer scaffold: tissue engineering application, Industrial & Engineering Chemistry Research. (2019) 58, no. 16, 6163–6194, https://doi.org/10.1021/acs.iecr.8b05334, 2-s2.0-85065637335.
- 131 Goonoo N., Bhaw-Luximon A., Bowlin G. L., and Jhurry D., An assessment of biopolymer- and synthetic polymer-based scaffolds for bone and vascular tissue engineering, Polymer International. (2013) 62, no. 4, 523–533, https://doi.org/10.1002/pi.4474, 2-s2.0-84875492180.
- 132 Swetha M., Sahithi K., Moorthi A., Srinivasan N., Ramasamy K., and Selvamurugan N., Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering, International Journal of Biological Macromolecules. (2010) 47, no. 1, 1–4, https://doi.org/10.1016/j.ijbiomac.2010.03.015, 2-s2.0-77953021249, 20361991.
- 133 Li D., Liu T., Yu X., Wu D., and Zhiqiang S., Fabrication of graphene–biomacromolecule hybrid materials for tissue engineering application, Polymer Chemistry. (2017) 8, no. 30, 4309–4321, https://doi.org/10.1039/C7PY00935F, 2-s2.0-85026799284.
- 134 Velema J. and Kaplan D., Biopolymer-based biomaterials as scaffolds for tissue engineering, Tissue Engineering I, 2006, Springer, 187–238.
- 135 Mokhtarzadeh A., Alibakhshi A., Hejazi M., Omidi Y., and Dolatabadi J. E. N., Bacterial-derived biopolymers: advanced natural nanomaterials for drug delivery and tissue engineering, TrAC Trends in Analytical Chemistry. (2016) 82, 367–384, https://doi.org/10.1016/j.trac.2016.06.013, 2-s2.0-84977140452.
- 136
Devi M.,
Amutheesan M.,
Govindhan R., and
Karthikeyan B., A review of three-dimensional printing for biomedical and tissue engineering applications, The Open Biotechnology Journal. (2018) 12, no. 1, 241–255, https://doi.org/10.2174/1874070701812010241, 2-s2.0-85061730333.
10.2174/1874070701812010241 Google Scholar
- 137
Kolan K.,
Liu Y.,
Baldridge J.,
Murphy C.,
Semon J.,
Day D., and
Leu M., Solvent based 3D printing of biopolymer/bioactive glass composite and hydrogel for tissue engineering applications, Procedia CIRP. (2017) 65, 38–43, https://doi.org/10.1016/j.procir.2017.04.022, 2-s2.0-85029711041.
10.1016/j.procir.2017.04.022 Google Scholar
- 138 Ahmed T. A. E., Dare E. V., and Hincke M., Fibrin: a versatile scaffold for tissue engineering applications, Tissue Engineering Part B: Reviews. (2008) 14, no. 2, 199–215, https://doi.org/10.1089/ten.teb.2007.0435, 2-s2.0-45249084145, 18544016.
- 139 Sell S. A., McClure M. J., Garg K., Wolfe P. S., and Bowlin G. L., Electrospinning of collagen/biopolymers for regenerative medicine and cardiovascular tissue engineering, Advanced Drug Delivery Reviews. (2009) 61, no. 12, 1007–1019, https://doi.org/10.1016/j.addr.2009.07.012, 2-s2.0-70349968105, 19651166.
- 140 Gomes S., Leonor I. B., Mano J. F., Reis R. L., and Kaplan D. L., Natural and genetically engineered proteins for tissue engineering, Progress in Polymer Science. (2012) 37, no. 1, 1–17, https://doi.org/10.1016/j.progpolymsci.2011.07.003, 2-s2.0-80455174726, 22058578.
- 141 Kumar A., Mandal S., Barui S., Vasireddi R., Gbureck U., Gelinsky M., and Basu B., Low temperature additive manufacturing of three dimensional scaffolds for bone-tissue engineering applications: processing related challenges and property assessment, Materials Science and Engineering: R: Reports. (2016) 103, 1–39, https://doi.org/10.1016/j.mser.2016.01.001, 2-s2.0-84959465947.
- 142 LogithKumar R., KeshavNarayan A., Dhivya S., Chawla A., Saravanan S., and Selvamurugan N., A review of chitosan and its derivatives in bone tissue engineering, Carbohydrate Polymers. (2016) 151, 172–188, https://doi.org/10.1016/j.carbpol.2016.05.049, 2-s2.0-84973138789, 27474556.
- 143 Nosrati H., Pourmotabed S., and Sharifi E., A review on some natural biopolymers and their applications in angiogenesis and tissue engineering, Journal of Applied Biotechnology Reports. (2018) 5, no. 3, 81–91, https://doi.org/10.29252/JABR.05.03.01, 2-s2.0-85067008762.
- 144 Salerno A. and Pascual C. D., Bio-based polymers, supercritical fluids and tissue engineering, Process Biochemistry. (2015) 50, no. 5, 826–838, https://doi.org/10.1016/j.procbio.2015.02.009, 2-s2.0-84937210451.
- 145 Khan M., Aslam A., Mehboob H., Razak S. I. A., Yahya M., Yusof A. H. M., Ramlee M. H., Anand T. J. S., Hassan R., Aziz A., and Amin R., Development of polymeric nanocomposite (xyloglucan-co-methacrylic acid/hydroxyapatite/SiO2) scaffold for bone tissue engineering applications—in-vitro antibacterial, cytotoxicity and cell culture evaluation, Polymers. (2020) 12.
- 146 Law J. X., Liau L. L., Saim A., Yang Y., and Idrus R., Electrospun collagen nanofibers and their applications in skin tissue engineering, Tissue Engineering and Regenerative Medicine. (2017) 14, no. 6, 699–718, https://doi.org/10.1007/s13770-017-0075-9, 2-s2.0-85037068321, 30603521.
- 147 Olad A. and Hagh H. B. K., Graphene oxide and amin-modified graphene oxide incorporated chitosan-gelatin scaffolds as promising materials for tissue engineering, Composites. Part B, Engineering. (2019) 162, 692–702, https://doi.org/10.1016/j.compositesb.2019.01.040, 2-s2.0-85059882206.
- 148 Wang J., Bai J., Fan M., Li T., Li Y., Qian H., Wang L., Zhang H., Qi X., and Rao Z., Cereal-derived arabinoxylans: structural features and structure-activity correlations, Trends in Food Science and Technology. (2020) 96, 157–165, https://doi.org/10.1016/j.tifs.2019.12.016.
- 149 Song Y., Wu H., Gao Y., Li J., Lin K., Liu B., Lei X., Cheng P., Zhang S., and Wang Y., Zinc silicate/nano-hydroxyapatite/collagen scaffolds promote angiogenesis and bone regeneration via the p38 MAPK pathway in activated monocytes, ACS Applied Materials & Interfaces. (2020) 12, no. 14, 16058–16075, https://doi.org/10.1021/acsami.0c00470, 32182418.
- 150 Bourquin V., Nishikubo N., Abe H., Brumer H., Denman S., Eklund M., Christiernin M., Teeri T. T., Sundberg B., and Mellerowicz E. J., Xyloglucan endotransglycosylases have a function during the formation of secondary cell walls of vascular tissues, The Plant Cell. (2002) 14, no. 12, 3073–3088, https://doi.org/10.1105/tpc.007773, 2-s2.0-0036914894, 12468728.
- 151 Underwood S., Afoke A., Brown R., MacLeod A., Shamlou P. A., and Dunnill P., Wet extrusion of fibronectin-fibrinogen cables for application in tissue engineering, Biotechnology and Bioengineering. (2001) 73, no. 4, 295–305, https://doi.org/10.1002/bit.1062, 2-s2.0-0035918612, 11283912.
- 152 Balakrishnan B., Mohanty M., Umashankar P., and Jayakrishnan A., Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin, Biomaterials. (2005) 26, no. 32, 6335–6342, https://doi.org/10.1016/j.biomaterials.2005.04.012, 2-s2.0-20444501659, 15919113.
- 153 Patrulea V., Ostafe V., Borchard G., and Jordan O., Chitosan as a starting material for wound healing applications, European Journal of Pharmaceutics and Biopharmaceutics. (2015) 97, no. Part B, 417–426, https://doi.org/10.1016/j.ejpb.2015.08.004, 2-s2.0-84947921812, 26614560.
- 154 Stapelfeldt K., Stamboroski S., Walter I., Suter N., Kowalik T., Michaelis M., and Bruüggemann D., Controlling the multiscale structure of nanofibrous fibrinogen scaffolds for wound healing, Nano Letters. (2019) 19, no. 9, 6554–6563, https://doi.org/10.1021/acs.nanolett.9b02798, 2-s2.0-85072133767, 31418579.
- 155
Kocaaga B.,
Kurkcuoglu O.,
Tatlier M.,
Batirel S., and
Guner F. S., Low-methoxyl pectin–zeolite hydrogels controlling drug release promotein vitrowound healing, Journal of Applied Polymer Science. (2019) 136, no. 24, https://doi.org/10.1002/app.47640, 2-s2.0-85063099859.
10.1002/app.47640 Google Scholar
- 156 Khalid A., Dongbi B., Abraham A., Jadhav A., Linklater D., Matusica A. D., Nguyen D., Murdoch B., Zakhartchouk N., Dekiwadia C., Reineck P., Simpson D., Vidanapathirana A. K., Houshyar S., Bursill C., Ivanova E., and Gibson B., Electrospun nanodiamond-silk fibroin membranes: a multifunctional platform for biosensing and wound-healing applications, ACS Applied Materials & Interfaces. (2020) 12, no. 43, 48408–48419, https://doi.org/10.1021/acsami.0c15612, 33047948.
- 157 He W., Wu J., Xu J., Mosselhy D. A., Zheng Y., and Yang S., Bacterial cellulose: functional modification and wound healing applications, Advances in Wound Care. (2021) 10, 623–640, https://doi.org/10.1089/wound.2020.1219.
- 158 Sapkota S. and Chou S., Electrospun chitosan-based fibers for wound healing applications, Journal of Biomaterials. (2020) 4, no. 2, 51–57, 34056619.
- 159 Auddy R. G., Abdullah M. F., Das S., Roy P., Datta S., and Mukherjee A., New guar biopolymer silver nanocomposites for wound healing applications, BioMed Research International. (2013) 2013, 8, https://doi.org/10.1155/2013/912458, 2-s2.0-84885577493, 912458, 24175306.
- 160 Varaprasad K., Jayaramudu T., Kanikireddy V., Toro C., and Sadiku E., Alginate-based composite materials for wound dressing application:a mini review, Carbohydrate Polymers. (2020) 236, article 116025, https://doi.org/10.1016/j.carbpol.2020.116025.
- 161 Gilotra S., Chouhan D., Bhardwaj N., Nandi S., and Mandal B., Potential of silk sericin based nanofibrous mats for wound dressing applications, Materials Science & Engineering. C, Materials for Biological Applications. (2018) 90, 420–432, https://doi.org/10.1016/j.msec.2018.04.077, 2-s2.0-85046496722, 29853108.
- 162 Bakhsheshi-Rad H., Ismail A., Aziz M., Akbari M., Hadisi Z., Omidi M., and Chen X., Development of the PVA/CS nanofibers containing silk protein sericin as a wound dressing: in vitro and in vivo assessment, International Journal of Biological Macromolecules. (2020) 149, 513–521, https://doi.org/10.1016/j.ijbiomac.2020.01.139, 31954780.
- 163 Iacob A., Drăgan M., Ionescu O., Profire L., Ficai A., Andronescu E., Confederat L., and Lupașcu D., An overview of biopolymeric electrospun nanofibers based on polysaccharides for wound healing management, Pharmaceutics. (2020) 12, no. 10, https://doi.org/10.3390/pharmaceutics12100983, 33080849.
- 164 Ahmed M., Zayed M., El-Dek S., Hady M. A., El Sherbiny D. H., and Uskoković V., Nanofibrous ε-polycaprolactone scaffolds containing Ag-doped magnetite nanoparticles: physicochemical characterization and biological testing for wound dressing applications in vitro and in vivo, Bioactive Materials. (2021) 6, no. 7, 2070–2088, https://doi.org/10.1016/j.bioactmat.2020.12.026, 33511308.
- 165 El-Hamshary H., El-Naggar M., El-Faham A., Abu-Saied M., Ahmed M. K., and Al-Sahly M., Preparation and characterization of nanofibrous scaffolds of Ag/vanadate hydroxyapatite encapsulated into polycaprolactone: morphology, mechanical, and in vitro cells adhesion, Polymers. (2021) 13, no. 8, https://doi.org/10.3390/polym13081327, 33919554.
- 166 Jeckson T. A., Neo Y., Sisinthy S. P., and Gorain B., Delivery of therapeutics from layer-by-layer electrospun nanofiber matrix for wound healing: an update, Journal of Pharmaceutical Sciences. (2020) 110, 635–653, https://doi.org/10.1016/j.xphs.2020.10.003.
- 167 Lemraski E. G., Hossein J., Dashti M., Khajehali E., Sharafinia S., Rafiee-Moghaddam R., and Webster T., Antimicrobial double-layer wound dressing based on chitosan/polyvinyl alcohol/copper: in vitro and in vivo assessment, International Journal of Nanomedicine. (2021) 16, 223–235, https://doi.org/10.2147/IJN.S266692, 33469282.
- 168 Matei E., Gaidău C., Râpă M., Constantinescu R., Savin S., Berechet M., Predescu A., Berbecaru A., Coman G., and Predescu C., Sustainable rabbit skin glue to produce bioactive nanofibers for nonactive wound dressings, Materials. (2020) 13, no. 23, https://doi.org/10.3390/ma13235388, 33260877.
- 169 Duong V.-T., Kim J. P., Kim K., Ko H., Hwang C. H., and Koo K.-I., Three-dimensional bio-printing technique: trend and potential for high volume implantable tissue generation, Journal of Biomedical Engineering Research. (2018) 39, no. 5, 188–207.
- 170 Starmer C., Stead A., Wyngaarden J., Greenfield J., Krinsky, Ivanitsky ′s Leadership In, and Pushchino, A Biased History of the Physics of Neuro- and Cardiac Electrophysiology, Medical University of South Carolina.
- 171 Xie Z., Gao M., Lobo A., and Webster T., 3D bioprinting in tissue engineering for medical applications: the classic and the hybrid, Polymers. (2020) 12, no. 8, https://doi.org/10.3390/polym12081717, 32751797.
- 172
Babbar A.,
Jain V.,
Gupta D.,
Prakash C.,
Singh S., and
Sharma A., 3D bioprinting in pharmaceuticals, medicine, and tissue engineering applications, Advanced Manufacturing and Processing Technology, 2020, CRC Press, 147–161.
10.1201/9780429298042-7 Google Scholar
- 173 Wang Z., Kapadia W., Li C., Lin F., Pereira R., Granja P., Sarmento B., and Cui W., Tissue-specific engineering: 3D bioprinting in regenerative medicine, Journal of Controlled Release. (2020) 329, 237–256.
- 174 Bishop E. S., Mostafa S., Pakvasa M., Luu H., Lee M. J., Wolf J. M., Ameer G., He T., and Reid R., 3-D bioprinting technologies in tissue engineering and regenerative medicine: current and future trends, Genes & Diseases. (2017) 4, no. 4, 185–195, https://doi.org/10.1016/j.gendis.2017.10.002, 2-s2.0-85034783934, 29911158.
- 175
Silva M.,
Pinho I. S.,
Covas J. A.,
Alves N. M., and
Paiva M. C., 3D printing of graphene-based polymeric nanocomposites for biomedical applications, Functional Composite Materials. (2021) 2, no. 1, 1–21.
10.1186/s42252-021-00020-6 Google Scholar
- 176 Wang X., Rivera-Bolaños N., Jiang B., and Ameer G., Advanced functional biomaterials for stem cell delivery in regenerative engineering and medicine, Advanced Functional Materials. (2019) 29, no. 23, article 1809009, https://doi.org/10.1002/adfm.201809009, 2-s2.0-85062975399.
- 177 Chung R. T., Development of advanced functional biomaterials, 2019, Naval Academy Annapolis MD Annapolis.
- 178 Sharma K., Mujawar M., and Kaushik A., State-of-art functional biomaterials for tissue engineering, Frontiers in Materials. (2019) 6, https://doi.org/10.3389/fmats.2019.00172, 2-s2.0-85072220032.
- 179 Wang Y., Chen G., Zhang H., Zhao C., Sun L., and Zhao Y., Emerging functional biomaterials as medical patches, ACS Nano. (2021) 15, no. 4, 5977–6007.
- 180 Lendlein A., Pierce B. F., Ambrosio L., and Grijpma D., Advanced functional polymers for medicine: multifunctional biomaterials, Acta Biomaterialia. (2012) 8, no. 12, article 4199, https://doi.org/10.1016/j.actbio.2012.09.036, 2-s2.0-84868092720, 23036946.
- 181 Raucci M., D′Amora U., Ronca A., and Ambrosio L., Injectable functional biomaterials for minimally invasive surgery, Advanced Healthcare Materials. (2020) 9, no. 13, article e2000349.
- 182 Gopinathan J. and Noh I., Recent trends in bioinks for 3D printing, Biomaterials Research. (2018) 22, no. 1, 1–15.
- 183
Seale N. M.,
Zeng Y., and
Varghese S., Biomimetic tissue engineering for musculoskeletal tissues, Developmental Biology and Musculoskeletal Tissue Engineering, 2018, Academic Press, 207–223.
10.1016/B978-0-12-811467-4.00009-7 Google Scholar
- 184 Katyal P., Mahmoudinobar F., and Montclare J., Recent trends in peptide and protein-based hydrogels, Current Opinion in Structural Biology. (2020) 63, 97–105, https://doi.org/10.1016/j.sbi.2020.04.007, 32512499.
- 185 Doğan E., Bhusal A., Cecen B., and Miri A., 3D printing metamaterials towards tissue engineering, Applied Materials Today. (2020) 20, article 100752, https://doi.org/10.1016/j.apmt.2020.100752.
- 186 Sivashanmugam A., Kumar R. A., Priya M. V., Nair S., and Jayakumar R., An overview of injectable polymeric hydrogels for tissue engineering, European Polymer Journal. (2015) 72, 543–565, https://doi.org/10.1016/j.eurpolymj.2015.05.014, 2-s2.0-84945442240.
- 187 Kumar S., Nehra M., Kedia D., Dilbaghi N., Tankeshwar K., and Kim K.-H., Nanotechnology-based biomaterials for orthopaedic applications: recent advances and future prospects, Materials Science & Engineering. C, Materials for Biological Applications. (2020) 106, article 110154, https://doi.org/10.1016/j.msec.2019.110154.
- 188
Patel J.,
Sheth T.,
Thakore D., and
Dhamat D., Biomimetics in endodontics: a review of the changing trends in endodontics, Journal of Advanced Oral Research. (2018) 9, no. 1-2, 11–14, https://doi.org/10.1177/2320206818816186.
10.1177/2320206818816186 Google Scholar
- 189 Mukherjee N., Adak A., and Ghosh S., Recent trends in the development of peptide and protein-based hydrogel therapeutics for the healing of CNS injury, Soft Matter. (2020) 16, no. 44, 10046–10064, https://doi.org/10.1039/D0SM00885K, 32724981.
- 190 Muthukrishnan L., Imminent antimicrobial bioink deploying cellulose, alginate, EPS and synthetic polymers for 3D bioprinting of tissue constructs, Carbohydrate Polymers. (2021) 260, https://doi.org/10.1016/j.carbpol.2021.117774.
- 191 Lim J.-O., Huh J., Abdi S. I. H., Ng S., and Yoo J. J., Functionalized biomaterials-oxygen releasing scaffolds, Journal of Biotechnology & Biomaterials. (2015) 5, 1–11.
- 192
Birla R., Bioengineered bioartificial ventricles, Tissue Engineering for the Heart, 2016, Springer, Cham, 199–226.
10.1007/978-3-319-41504-8_7 Google Scholar
- 193 GV S., Borovkov V. N., Eremin A. V., Orlov A. A., and Saburina I. N., The stimulation of reparative regeneration in the treatment of fractures of the extremities with the use of new biotechnologies, Patologicheskaia Fiziologiia i Èksperimental′naia Terapiia. (2013) 81.
- 194 Ma J., Noh I., Lee I., and Zhang S., Frontiers in regenerative medical materials: comments from the participants of the 2014 China-Korea Symposium on Biomimetic and Regenerative Medical materials, Regenerative Biomaterials. (2015) 2, no. 1, 71–76, https://doi.org/10.1093/rb/rbu020, 26816632.
- 195 Anju S., Prajitha N., Sukanya V., and Mohanan P., Complicity of degradable polymers in health-care applications, Materials Today Chemistry. (2020) 16, https://doi.org/10.1016/j.mtchem.2019.100236.
- 196
Mahfouzi S.,
Tali S. A. S., and
Amoabediny G., 3D bioprinting for lung and tracheal tissue engineering: criteria, advances, challenges, and future directions, Bioprinting. (2021) 21, article e00124, https://doi.org/10.1016/j.bprint.2020.e00124.
10.1016/j.bprint.2020.e00124 Google Scholar
- 197 Tatara A., Kontoyiannis D., and Mikos A., Drug delivery and tissue engineering to promote wound healing in the immunocompromised host: current challenges and future directions, Advanced Drug Delivery Reviews. (2018) 129, 319–329, https://doi.org/10.1016/j.addr.2017.12.001, 2-s2.0-85037746057, 29221962.
- 198
Moshiri A.,
Oryan A., and
Shahrezaee M., An overview on bone tissue engineering and regenerative medicine: current challenges, future directions and strategies, Journal of Sports Medicine & Doping Studies. (2015) 5, https://doi.org/10.4172/2161-0673.1000e144.
10.4172/2161-0673.1000e144 Google Scholar
- 199 Zhang J., Liu Y., Chen Y., Yuan L., He L., Wang J., Liu Q., and Zhang Y., Adipose-derived stem cells: current applications and future directions in the regeneration of multiple tissues, Stem Cells International. (2020) 2020, 26, 8810813, https://doi.org/10.1155/2020/8810813, 33488736.
