Traditional Chinese Medicines

Special Collections
15 February 2025
7 July 2025

Guest editor

  • Baoxue Yang

Pharmacology of Traditional Chinese Medicines (TCM) represents a unique and comprehensive field that integrates the study of medicinal substances derived from natural sources, with the understanding of their pharmacological effects and mechanisms of action. Modern pharmacological research employs a range of techniques, including in vitro and in vivo studies, as well as clinical trials, to elucidate the active components, pharmacological effects, and safety profiles of TCM substances, which has led to the discovery of new drugs and therapeutic strategies, as well as a deeper understanding of the molecular basis of TCM.

To drive innovation and potential novel therapeutic breakthroughs in TCM, Basic & Clinical Pharmacology & Toxicology (BCPT) will host a special collection focusing on pharmacology and toxicology in TCM. Original articles, focused reviews and short communications from the field of TCM are considered for this special collection. Please consult the BCPT author guidelines and the most recent “BCPT policy for experimental and clinical studies” and the BCPT policy for natural products “BCPT perspectives on studies involving natural products, traditional Chinese medicine and systems pharmacology” for more information.

Submission deadline: 31 December 2025

Contact information:

Baoxue Yang: [email protected]

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Articles

Eugenol Alleviates Cerebral Ischemia–Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up-Regulating Tripartite Motif Protein 59

Mengtian Pan,  Xiang Li,  Xinjuan Tian,  Lele Zixin Yang,  Weirong Fang, 
Free Access

Traditional Chinese Medicine for Anti-Arrhythmias: Mechanisms via Potassium Channels

Chenhao Gao,  Ting Xu,  Lingyu Linda Ye,  Dayue Darrel Duan, 
Free Access

Application of Artificial Intelligence in the Development of Traditional Chinese Medicine

Xuebing He,  Mingna Sun,  Tungalag Battulga,  Brent R. Copp,  Dilobarkhon Kodirova Rustamovna,  Hongyan Li,  Sagdullaev Shamansur Shahsaidovich,  Janar Jenis,  Yuqing Wang,  Lu Liang,  Jianye Zhang, 
Free Access

Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic-Related Diseases

Yukun Zhang,  Yang Yao,  Qiaoling Zhang,  Baoxue Yang, 

Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease

Fangling Sun,  Yifu Ma,  Dan Li,  Qianqian Yang,  Tingwei Yuan,  Tingting Liu,  Xin Tian,  Zixin Zhu,  Wenrong Zheng,  Yufeng Wang,  Wen Wang, 
Open Access

Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma

Mengjie Guo,  Han Meng,  Yi Sun,  Lianxin Zhou,  Tingting Hu,  Tianyi Yu,  Haowen Bai,  Yuanjiao Zhang,  Chunyan Gu,  Ye Yang, 
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma

USP13 is a promising therapeutic target for cellular proliferation in multiple myeloma. Bruceine A can retard the development of multiple myeloma by targeting USP13/PARP1-mediated DNA damage repair and triggering cell apoptosis.

Baicalin Ameliorates L-Glutamate-Induced Hippocampal Oxidative Stress Injury and Apoptosis in Mice by Regulating Nrf2/HO-1 Signalling Pathway

Feng Li,  Zishan Huang,  Huanyu Gou,  Jiarui Zheng,  Mingjiang Yao, 

Tetrahydroxy Stilbene Glycoside Reduces Abeta Deposition by Modulating Microglia Activation and via TREM2/PI3K/AKT Pathway in APP/PS1 Mice

Ming Li,  Qihan Song,  Shanshan Jie,  Chenchen Wang,  Can Zhang,  Kexin Chi,  Yan Gao,  Tianzuo Li,