SLEEP

9 February 2025
10 February 2025

Table of Contents

Open Access

Cortical activation during the verbal fluency task for obstructive sleep apnea patients with depressive symptoms: A multi-channel fNIRS study

Cortical activation during the verbal fluency task for obstructive sleep apnea patients with depressive symptoms: A multi-channel fNIRS study

Our study investigated the relationship between brain function and depression in OSA patients. The functional near-infrared spectroscopy was used to monitor the concentration of Oxy-Hb in the brain, whereas the participants performed the verbal fluency task, and the degree of depression was scored using the 17-item Hamilton Rating Scale for Depression. The right frontal polar region may be significant in assessing depressive symptoms in patients with OSA.

Open Access

Association Between Dietary Fiber Intake and Sleep Disorders: Based on the NHANES Database

Association Between Dietary Fiber Intake and Sleep Disorders: Based on the NHANES Database

This study utilizes data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2009 and 2014 to explore the association between dietary fiber intake and sleep disorders. The independent variable is dietary fiber intake, while the dependent variable is sleep disorders. Logistic regression analysis was employed to construct a relationship model between dietary fiber intake and sleep disorders, and stratified analysis was conducted on covariates to assess their impact on the model. The results indicate that increased dietary fiber intake is significantly negatively correlated with the risk of sleep disorders. Among women, particularly in the postmenopausal group with a BMI greater than 30 kg/m2, the effect of dietary fiber intake on improving sleep disorders is more pronounced. This study provides new dietary intervention ideas for improving sleep quality.

Open Access

High compassion predicts fewer sleep difficulties: A general population study with an 11-year follow-up

High compassion predicts fewer sleep difficulties: A general population study with an 11-year follow-up

Compassion is associated with better sleep and can protect against sleep difficulties. The protective effect of compassion may emerge due to fewer depressive symptoms.

Open Access

Circadian rhythm of daytime sleepiness in pediatric narcolepsy: A pilot study

Circadian rhythm of daytime sleepiness in pediatric narcolepsy: A pilot study

Changes based on the circadian rhythm of sleepiness of the pediatric narcoleptic patients should be made in the treatment strategy. In addition, regulating the secretion of melatonin could serve as a promising treatment to relieve sleepiness in the future.

Open Access

Exploring the Relationship of Smartphone Addiction on Attention Deficit, Hyperactivity Symptoms, and Sleep Quality Among University Students: A Cross-Sectional Study

Exploring the Relationship of Smartphone Addiction on Attention Deficit, Hyperactivity Symptoms, and Sleep Quality Among University Students: A Cross-Sectional Study

Smartphone addiction is common among university students. In addition, students with smartphone addiction are more likely to show symptoms of ADHD. Smoking, a preference for smartphones as a screen, and long daily screen exposure impair sleep quality.

Open Access

Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice

Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice

The main finding of our present study is that the deletion of Ctnnd2 gene in mice could lead social interaction disorders, repetitive behaviors, less exploration behaviors and defects in spatial cognition. Besides, the growth of dendritic spines and synapses in prefrontal cortex(PFC) are significantly impaired in Ctnnd2 KO mice. Next, we find that some of these phenotypes in WT and Ctnnd2 KO mice were also influenced by chronic sleep restriction, which is similarly to that seen in human with autism. Finally, we observe that PI3K/Akt-mTOR signal pathway was inhibited in Ctnnd2 KO mice, and chronic sleep restriction may regulate the development of dendritic spines and synapses mediated by PI3K/Akt-mTOR signal pathway.

Open Access

Improvements in Sleep Quality in Patients With Major Depressive and Generalized Anxiety Disorders Treated With Individualized, Parcel-Guided Transcranial Magnetic Stimulation

Improvements in Sleep Quality in Patients With Major Depressive and Generalized Anxiety Disorders Treated With Individualized, Parcel-Guided Transcranial Magnetic Stimulation

Our retrospective study found that a personalized parcel-guided approach to repetitive transcranial magnetic stimulation for the treatment of affective disorders is associated with improvement in sleep quality in addition to affective symptoms and quality of life.

Open Access

Volumetric analysis of the hypothalamic subunits in obstructive sleep apnea

Volumetric analysis of the hypothalamic subunits in obstructive sleep apnea

After hypothalamic subunits segmentation, several important correlations were identified in the OSA patients. These correlations suggest that factors related to sleep apnea severity could affect hypothalamic structure in patients.

Open Access

High Body Roundness Index Is Associated With Unhealthy Sleep Patterns: Insights From NHANES (2007–2014)

High Body Roundness Index Is Associated With Unhealthy Sleep Patterns: Insights From NHANES (2007–2014)

This study identifies a positive association between high body roundness index (BRI) and unhealthy sleep patterns in US adults, highlighting BRI's potential as a metric for sleep health evaluation.

Open Access

Complications following REM sleep behavior disorder

Complications following REM sleep behavior disorder

REM sleep behavior disorder (RBD) is gaining increasing attention as important prodromal marker for the development of neurodegenerative disorders such as Parkinson's Disease. However, the clinical relevance of this disorder and its association with other prodromal markers is often underestimated in clinical routine. We here report a case of severe clinical complications following extensive nocturnal movements due to RBD, aggravated by occurrence of additional prodromal nonmotor symptoms.

Open Access

Subsequent maternal sleep deprivation aggravates cognitive impairment by modulating hippocampal neuroinflammatory responses and synaptic function in maternal isoflurane-exposed offspring mice

Subsequent maternal sleep deprivation aggravates cognitive impairment by modulating hippocampal neuroinflammatory responses and synaptic function in maternal isoflurane-exposed offspring mice

Maternal sleep deprivation aggravated the cognitive deficits induced by maternal isoflurane exposure in male offspring mice, and these results were associated with neuroinflammation and alternations in synaptic function.

Open Access

Ocular emotion discrimination disorders in self-limited epilepsy patients with centrotemporal spikes complicated with electrical status epilepticus during sleep: A pediatric neuropsychological study

Ocular emotion discrimination disorders in self-limited epilepsy patients with centrotemporal spikes complicated with electrical status epilepticus during sleep: A pediatric neuropsychological study

SeLECTS complicated with ESES was associated with more extense emotional (sadness, fear, disgust, and surprise) recognition impairment in the eye region. The higher the SWI, the younger the onset age and the longer the duration of ESES, while the more the number of seizures, the more serious the impairment of emotional recognition function in the affected eye area.

Open Access

Relationship of Autophagic Dysfunction With the Quality of Life and Sleep, Depression and Disease Severity in Patients With Restless Legs Syndrome

Relationship of Autophagic Dysfunction With the Quality of Life and Sleep, Depression and Disease Severity in Patients With Restless Legs Syndrome

In summary, autophagy may play a crucial role in the development of Restless Legs Syndrome (RLS). Autophagic dysfunction is associated with a worse quality of life, disturbed sleep, and the severity of the disease in patients with RLS. Autophagy-related Protein 3 (ATG3) and Autophagy-related Protein 5 (ATG5) may serve as prognostic or diagnostic markers for RLS. Upregulated ATG5 expressions are associated with depression status in RLS.

Open Access

rTMS targeted to the secondary somatosensory cortex influences sleep in CRPS patients, as measured with the OURA ring

rTMS targeted to the secondary somatosensory cortex influences sleep in CRPS patients, as measured with the OURA ring

Repetitive transcranial magnetic stimulation (rTMS) targeted at the secondary somatosensory cortex decreased sleep restlessness in patients with complex regional pain syndrome. A multivariate analysis of OURA parameters revealed that assessing multiple sleep-related parameters concurrently can be beneficial when analyzing rTMS effects on sleep.

Open Access

Rapid eye movement dependency is associated with increased inflammatory activity in obstructive sleep apnea syndrome

Rapid eye movement dependency is associated with increased inflammatory activity in obstructive sleep apnea syndrome

REM-dependent OSAS has some typical characteristics that distinguish it from stage-independent OSAS. These include a preference for younger age, female gender, and milder disease severity. Although these features suggest a benign course for this phenotype, recent literature shows that it is also associated with various cardiometabolic consequences. In our retrospective study, we found that PDW and SII, two accessible blood parameters, indicate an increased inflammatory status in this subtype. Our results highlight the need for close follow-up in patients with REM-dependent OSAS, as increased systemic inflammation can have negative consequences.

Open Access

Correlation of diffusion tensor tractography with obstructive sleep apnea severity

Correlation of diffusion tensor tractography with obstructive sleep apnea severity

Correlation of diffusion tensor tractography with obstructive sleep apnea severity Bong Soo Park, Dong Ah Lee, Ho-Joon Lee, Jinseung Kim, Junghae Ko, Won Hee Lee, Jiyae Yi, Kang Min Park* Using correlation tractography, this study aimed to find statistically significant correlations between white matter (WM) tracts in participants with obstructive sleep apnea (OSA) and OSA severity. Connectometry analysis revealed that the AHI in participants with OSA was negatively correlated with FA-values in WM tracts. Connectometry analyses are valuable tools for detecting WM changes in sleep disorders.

Open Access

Accelerometer-derived sleep measures in idiopathic dystonia: A UK Biobank cohort study

Accelerometer-derived sleep measures in idiopathic dystonia: A UK Biobank cohort study

Accelerometer-derived sleep measures in idiopathic dystonia: A UK Biobank cohort study. Grace A Bailey, Megan E Wadon, Sandra Komarzynski, Claare Matthews, Elin Haf Davies, Kathryn J Peall.* No previous studies have examined sleep in an idiopathic dystonia cohort using objectives measures derived from wrist worn accelerometers. We made us of the large UK Biobank dataset to undertake this work at scale. Data from 241 dystonia aand 964 matched controls were compared, identifying later sleep times, reduced time in bed and shifts in circadian rhythms in those diagnosed with dystonia compared to controls, with these differences independent of reported pain.

Open Access

Factors correlated with excessive daytime sleepiness in patients with Parkinson's disease: A polysomnography study

Factors correlated with excessive daytime sleepiness in patients with Parkinson's disease: A polysomnography study

Our data revealed a close association between the respiratory-related microarousal index, FSS scores and EDS. It can be speculated that fragmented sleep and pathological abnormalities of the central nervous system with changes in arousal were major influencing factors of EDS in PD.