Post-Surgical Non-Invasive Wound Healing Monitoring in Oropharyngeal Mucosa
Anastasia Guryleva
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorAlexander Machikhin
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorYevgeniya Kulikova
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorCorresponding Author
Demid Khokhlov
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Correspondence:
Demid Khokhlov ([email protected])
Search for more papers by this authorAnastasia Zolotukhina
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorAnastasia Guryleva
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorAlexander Machikhin
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorYevgeniya Kulikova
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorCorresponding Author
Demid Khokhlov
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Correspondence:
Demid Khokhlov ([email protected])
Search for more papers by this authorAnastasia Zolotukhina
Scientific and Technological Centre of Unique Instrumentation, Russian Academy of Sciences, Moscow, Russia
Search for more papers by this authorFunding: This work was supported by Ministry of Science and Higher Education of the Russian Federation (project FFNS-2024-0002).
ABSTRACT
Postoperative bleeding is the most significant complication of tonsillectomy. Regular monitoring of post-surgical wound healing in the pharynx is required. For this purpose, we propose endoscope-based non-invasive perfusion mapping and quantification. The combination of imaging photoplethysmography and image processing provides automated wound area selection and microcirculation characterization. In this feasibility study, we demonstrate the first results of the proposed approach to wound monitoring in clinical trial on eight patients after tonsillectomy. Combination of probe-based optical system and image processing algorithms can provide the valuable and consistent data on perfusion distribution. The quantitative microcirculation data obtained 1, 4, and 7 days after surgery are in good agreement with existing monitoring protocols.
Conflicts of Interest
The authors declare no conflicts of interest.
Open Research
Data Availability Statement
The data that support the findings of this study are available from the corresponding author upon reasonable request.
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