Highlight
Balancing C=C Functionalization and C=O Reduction in Cu−H Catalysis
Graphical Abstract
Coppercabana: The copper(I) hydride catalyzed functionalization of unactivated alkenes has been shown to be compatible with conventional carbonyl reduction. Through the combination of both pathways or complete suppression of C=O reduction in favor of C=C functionalization, methods for the stereoselective synthesis of a variety of chiral molecules have been developed.
