Volume 126, Issue 43 pp. 11776-11779
Zuschrift

Polydimethylsiloxane: A General Matrix for High-Performance Chromatographic NMR Spectroscopy

Dr. Shaohua Huang

Corresponding Author

Dr. Shaohua Huang

Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101 (China)

Shaohua Huang, Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101 (China)

Zhengwu Bai, School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430073 (China)

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Dr. Jun Gao

Dr. Jun Gao

Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101 (China)

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Rui Wu

Rui Wu

School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430073 (China)

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Prof. Dr. Shengying Li

Prof. Dr. Shengying Li

Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101 (China)

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Prof. Dr. Zhengwu Bai

Corresponding Author

Prof. Dr. Zhengwu Bai

School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430073 (China)

Shaohua Huang, Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101 (China)

Zhengwu Bai, School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430073 (China)

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First published: 04 September 2014
Citations: 6

This research was supported by the National Natural Science Foundation of China (grant number 21105108). We thank Dr. Lishan Yao and Dr. Sifu Tang (Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences) for helpful discussions.

Abstract

The detection and structural characterization of the components of a mixture is a challenging task. Therefore, the development of a facile and general method that enables both the separation and the structural characterization of the components is desired. Diffusion-ordered NMR spectroscopy (DOSY) with the aid of a matrix is a promising tool for this purpose. However, because the currently existing matrices only separate limited components, the application of the DOSY technique is restricted. Herein we introduce a new versatile matrix, poly(dimethylsiloxane), which can fully separate many mixtures of different structural types by liquid-state NMR spectroscopy. With poly(dimethylsiloxane), liquid-state chromatographic NMR spectroscopy could become a general approach for the structural elucidation of mixtures of compounds.

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