Mixed germ cell-sex cord stromal tumour of the testis, further evidence supporting similarity of the germ cell component to spermatocytic tumour: case report
Sarwat Gilani
Department of Pathology and Laboratory Medicine, UTHSCSA, San Antonio, TX, USA
Search for more papers by this authorSounak Gupta
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Search for more papers by this authorPatricia T Greipp
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Search for more papers by this authorSunil Patel
Department of Pathology, Lakeview Hospital, Regions Hospital, St. Paul, MN, USA
Search for more papers by this authorRafael E Jimenez
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Search for more papers by this authorCorresponding Author
Loren P Herrera Hernandez
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Address for correspondence: LP Herrera Hernandez, Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USA. e-mail: [email protected]
Search for more papers by this authorSarwat Gilani
Department of Pathology and Laboratory Medicine, UTHSCSA, San Antonio, TX, USA
Search for more papers by this authorSounak Gupta
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Search for more papers by this authorPatricia T Greipp
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Search for more papers by this authorSunil Patel
Department of Pathology, Lakeview Hospital, Regions Hospital, St. Paul, MN, USA
Search for more papers by this authorRafael E Jimenez
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Search for more papers by this authorCorresponding Author
Loren P Herrera Hernandez
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Address for correspondence: LP Herrera Hernandez, Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USA. e-mail: [email protected]
Search for more papers by this authorReferences
- 1Talerman A. Gonadal tumours composed of germ cells and sex cord stroma derivatives. Patol. Pol. 1979; 30; 221–228.
- 2Ulbright TM, Srigley JR, Reuter VE, Wojno K, Roth LM, Young RH. Sex cord-stromal tumors of the testis with entrapped germ cells: a lesion mimicking unclassified mixed germ cell sex cord-stromal tumors. Am. J. Surg. Pathol. 2000; 24; 535–542.
- 3Michalova K, McKenney JK, Kristiansen G et al. Novel insights into the mixed germ cell-sex cord stromal tumor of the testis: detection of chromosomal aneuploidy and further morphological evidence supporting the neoplastic nature of the germ cell component. Virchows Arch. 2020; 477; 615–623.
- 4Anderson WJ, Maclean FM, Acosta AM, Hirsch MS. Expression of the C-terminal region of the SSX protein is a useful diagnostic biomarker for spermatocytic tumour. Histopathology 2021; 79; 700–707.
- 5Gupta S, Farooq A, Rowsey RA et al. Cytogenetics of spermatocytic tumors with a discussion of gain of chromosome 12p in anaplastic variants. Hum. Pathol. 2022; 124; 85–95.
- 6Siegmund S, Sholl LM, Cornejo KM et al. Molecular assessment of testicular adult granulosa cell tumor demonstrates significant differences when compared to ovarian counterparts. Mod. Pathol. 2022; 35; 697–704.
- 7Roth LM, Cheng L. Mixed germ cell-sex cord stromal tumour of the testis and ovary: comparison and contrast. Pathology 2021; 53; 166–169.
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