Volume 90, Issue 11 pp. 2279-2284
HEPATOPANCREATICOBILIARY SURGERY

Unsuspected choledocholithiasis found by routine intra-operative cholangiography during laparoscopic cholecystectomy

Robert S. O'Neill BMedSci, MBBS

Robert S. O'Neill BMedSci, MBBS

Upper GI Surgery Unit, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Sarah Z. Wennmacker MD, PhD

Sarah Z. Wennmacker MD, PhD

Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands

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Nazim Bhimani MBiostat, BSc (Adv Sci) (Hons)

Nazim Bhimani MBiostat, BSc (Adv Sci) (Hons)

Upper GI Surgery Unit, Royal North Shore Hospital, Sydney, New South Wales, Australia

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Aafke H. van Dijk MD, PhD

Aafke H. van Dijk MD, PhD

Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands

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Philip de Reuver MD, PhD

Philip de Reuver MD, PhD

Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands

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Thomas J. Hugh MD, FRACS

Corresponding Author

Thomas J. Hugh MD, FRACS

Upper GI Surgery Unit, Royal North Shore Hospital, Sydney, New South Wales, Australia

Northern Clinical School, University of Sydney, Sydney, New South Wales, Australia

Correspondence

Dr Robert S. O'Neill, Upper GI Surgical Unit, Royal North Shore Hospital, St Leonards, NSW 2065, Australia. Email: [email protected]

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First published: 13 June 2020
Citations: 6
Robert S. O'Neill BMedSci, MBBS; Sarah Z. Wennmacker MD, PhD; N. Bhimani MBiostat, BSc (Adv Sci) (Hons); Aafke H. van Dijk MD, PhD; P. de Reuve MD, PhD; Thomas J. Hugh MD, FRACS.

Abstract

Background

The true incidence of unsuspected choledocholithiasis found during laparoscopic cholecystectomy (LC) is unknown. Untreated ‘silent’ stones may be associated with significant long-term risks. The aim of this study was to establish the incidence of unsuspected common bile duct stones (CBDS) and to determine the management and associated risk factors for unsuspected CBDS.

Methods

Retrospective review of a large consecutive series of patients from Australia who underwent LC in a tertiary referral setting. Percentages of unsuspected CBDS, management and complications were reported. Pre-operative and intra-operative factors associated with unsuspected CBDS were determined using multivariable logistic regression analysis.

Results

From a total of 1998 patients who underwent LC, 747 (37.4%) patients with no pre-operative suspicious factors were the subject of this study. CBDS were detected in 24 (3.2%) patients and all were managed either laparoscopically or endoscopically. Risk factors independently associated with unsuspected CBDS included patients >55 years of age (odds ratio 2.93, P = 0.038) and a large cystic duct size (odds ratio = 3.13, P < 0.001) on multivariable analysis.

Conclusion

The incidence of patients with unsuspected CBDS on intra-operative cholangiography is low. Complete clearance of these stones can be achieved using a combination of laparoscopic and endoscopic methods.

Conflicts of Interest

None declared.

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