Spiropyran-Conjugated Pluronic as a Dual Responsive Colorimetric Detector
Yeon Jeong Oh
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorJeong A. Nam
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorAbdullah Al-Nahain
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorSangkug Lee
Korea Institute of Industrial Technology, Republic of Korea
Search for more papers by this authorCorresponding Author
Insik In
Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Insik In, Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea.
Sung Young Park, Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorCorresponding Author
Sung Young Park
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Insik In, Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea.
Sung Young Park, Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorYeon Jeong Oh
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorJeong A. Nam
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorAbdullah Al-Nahain
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorSangkug Lee
Korea Institute of Industrial Technology, Republic of Korea
Search for more papers by this authorCorresponding Author
Insik In
Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Insik In, Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea.
Sung Young Park, Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorCorresponding Author
Sung Young Park
Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Insik In, Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea.
Sung Young Park, Department of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 380-702, Republic of Korea
Search for more papers by this authorAbstract
Novel spiropyran-conjugated Pluronic [polyethylene oxide (PEO)-b-polypropylene oxide (PPO)-b-polyethylene oxide (PEO)] micelles are developed as a new colorimetric detector showing photo- or thermo-switchable behavior. Facile conjugation of spiropyran to Pluronic was confirmed by 1H NMR, UV–Vis, and Fluorescence spectroscopy. A switchable photoluminescence is found depending on the irradiation with either UV or visible light, and temperature resulting from structural isomerization of spiropyran between spiropyran (SP) and merocyanine (MC) form. Cytotoxicity of the spiropyran-conjugated Pluronic (SP-PL) was evaluated following an MTT assay, whereas photo responsiveness of spiropyran within the micelles was determined by confocal laser scanning microscopy.
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