Inside Back Cover: Effects of temperature on multiparametric evaluation of hindlimb ischemia with dynamic fluorescence imaging (J. Biophotonics 6-7/2017)

Time-series fluorescence images are obtained to provide both anatomical and functional information. Perfusion vascular density (PVD), blood flow index (BFI) and mean fluorescence intensity (MFI) are quantitatively evaluated to distinguish normal and ischemic hindlimbs at different temperatures. This quantitative and comprehensive evaluation method may contribute to the diagnosis of vascular occlusive diseases and preclinical development of new drugs. Further details can be found in the article by Wenjuan Cai et al. on pp. 811–820.