Kinetics of Isophorone Synthesis via Self-Condensation of Supercritical Acetone
Jun Mei
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Search for more papers by this authorZhirong Chen
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Search for more papers by this authorShenfeng Yuan
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Search for more papers by this authorHaoran Li
Department of Chemistry, Zhejiang University, Hangzhou, China.
Search for more papers by this authorCorresponding Author
Hong Yin
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.Search for more papers by this authorJun Mei
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Search for more papers by this authorZhirong Chen
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Search for more papers by this authorShenfeng Yuan
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
Search for more papers by this authorHaoran Li
Department of Chemistry, Zhejiang University, Hangzhou, China.
Search for more papers by this authorCorresponding Author
Hong Yin
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.
College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, China.Search for more papers by this authorAbstract
A kinetic study on isophorone synthesis via self-condensation of supercritical acetone catalyzed by aqueous KOH in a tubular flow reactor was conducted. The intention was to improve the isophorone selectivity, with the main approach to reduce the by-products higher-boiling than isophorone. A higher isophorone selectivity was obtained with increased reaction temperature. The structures of main products were determined by gas chromatography-mass spectrometry and nuclear magnetic resonance analysis. The key reaction pathways and a corresponding kinetic model were proposed. The fitted apparent activation energies indicated the reason of isophorone selectivity improvement in that high temperature favors reversion of reversible by-products.
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