Mild C−H/C−C Activation by Z-Selective Cobalt Catalysis
Daniel Zell
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
These authors contributed equally to this work.
Search for more papers by this authorQingqing Bu
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
These authors contributed equally to this work.
Search for more papers by this authorDr. Milica Feldt
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
Search for more papers by this authorCorresponding Author
Prof. Dr. Lutz Ackermann
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
Search for more papers by this authorDaniel Zell
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
These authors contributed equally to this work.
Search for more papers by this authorQingqing Bu
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
These authors contributed equally to this work.
Search for more papers by this authorDr. Milica Feldt
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
Search for more papers by this authorCorresponding Author
Prof. Dr. Lutz Ackermann
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany
Search for more papers by this authorGraphical Abstract
Double activation: Challenging C−H/C−C functionalizations were achieved through the use of cobalt catalysis under exceedingly mild reaction conditions. This method leads to the formation of Z alkenes with unique chemo- and diastereoselectivity.
Abstract
Cationic cobalt complexes enable unprecedented cobalt-catalyzed C−H/C−C functionalizations with unique selectivity features. The versatile cobalt catalyst proved broadly applicable, enabled efficient C−H/C−C cleavage at room temperature, and delivered Z-alkenes with excellent diastereocontrol.
Supporting Information
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