Multiplexing Sensory Molecules Map Protons Near Micellar Membranes†
Seiichi Uchiyama Dr.
School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG (Northern Ireland), Fax: (+44) 28-9097-4687
Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan, Fax: (+81) 3-5841-4768
Search for more papers by this authorKaoru Iwai Prof. Dr.
Department of Chemistry, Faculty of Science, Nara Women's University, Kitauoya-Nishimachi, Nara 630-8506, Japan
Search for more papers by this authorA. Prasanna de Silva Prof. Dr.
School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG (Northern Ireland), Fax: (+44) 28-9097-4687
Search for more papers by this authorSeiichi Uchiyama Dr.
School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG (Northern Ireland), Fax: (+44) 28-9097-4687
Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan, Fax: (+81) 3-5841-4768
Search for more papers by this authorKaoru Iwai Prof. Dr.
Department of Chemistry, Faculty of Science, Nara Women's University, Kitauoya-Nishimachi, Nara 630-8506, Japan
Search for more papers by this authorA. Prasanna de Silva Prof. Dr.
School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG (Northern Ireland), Fax: (+44) 28-9097-4687
Search for more papers by this authorWe thank The Daiwa Anglo-Japanese Foundation, Invest NI (RTD COE 40) (Japan) Society for the promotion of Science, W. T. Silva and S. T. Herath for support and help.
Graphical Abstract
Hi-fi mapping: Multiplexing fluorescent sensors that simultaneously target proton concentration and polarity move to micellar nanospaces, self-regulate their positions, and report their pKa values and wavelengths, which are controlled by their local environments. Such sensory functions enable maps of proton gradients near micellar membranes to be drawn.
Supporting Information
Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z801516_s.pdf or from the author.
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