Gold-Catalyzed Hydroamination of Alkynes and Allenes with Parent Hydrazine†
Dr. Rei Kinjo
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/
Search for more papers by this authorBruno Donnadieu
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/
Search for more papers by this authorCorresponding Author
Prof. Guy Bertrand
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/Search for more papers by this authorDr. Rei Kinjo
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/
Search for more papers by this authorBruno Donnadieu
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/
Search for more papers by this authorCorresponding Author
Prof. Guy Bertrand
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/
UCR-CNRS Joint Research Chemistry Laboratory (UMI 2957), Department of Chemistry, University of California Riverside, Riverside, CA 92521-0403 (USA), Fax: (+1) 202-354-5267 http://research.chem.ucr.edu/groups/bertrand/guybertrandwebpage/Search for more papers by this authorWe are grateful to the DOE (DE-FG02-09ER16069) for financial support of this research, and to the Japan Society for the Promotion of Science for fellowships (R.K.).
Graphical Abstract
Bei der Addition von Hydrazin an Alkine, Diine, Enine und Allene in Gegenwart eines kationischen Gold(I)-Komplexes mit einem cyclischen (Alkyl)(amino)carben-Liganden bilden sich unterschiedliche stickstoffhaltige Verbindungen (siehe Schema; gezeigt ist auch die Molekülstruktur des Gold-Hydrazin-Komplexes im Kristall). Diese Hydroaminierung ist ein idealer erster Schritt für die Synthese acyclischer und heterocyclischer Grundchemikalien. Dipp=2,6-Diisopropylphenyl.
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