Volume 41, Issue 3 e12664
Original Article

Shelf-life prediction of microencapsulated Β-galactosidase powder prepared using enteric double-coating technology

Sung-Il Ahn

Sung-Il Ahn

Animal Products and Food Science Program, Division of Applied Animal Science, College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, South Korea

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Hae-Soo Kwak

Hae-Soo Kwak

Department of Food Science and Technology, Sejong University, Seoul 05006, South Korea

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Mohammad Al Mijan

Mohammad Al Mijan

Department of Marine Food Science and Technology, Gangneung-Wonju National University, Gangneung 25457, South Korea

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Jin-Woo Jhoo

Jin-Woo Jhoo

Animal Products and Food Science Program, Division of Applied Animal Science, College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, South Korea

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Gur-Yoo Kim

Gur-Yoo Kim

Animal Products and Food Science Program, Division of Applied Animal Science, College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, South Korea

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Chang-Six Ra

Corresponding Author

Chang-Six Ra

Division of Animal Resources, Kangwon National University, Chuncheon 24341, South Korea

Correspondence Chang-Six Ra, Division of Animal Resources, Kangwon National University, Chuncheon 24341, South Korea. Email: [email protected]Search for more papers by this author
First published: 07 December 2017
Citations: 5

Funding Information: Kangwon National University

Abstract

In this study, we estimated the storage period of enteric double-microencapsulated lactase (β-d-galactosidase) powder used to address lactose intolerance associated with milk. The coating materials were medium-chain triglyceride for the primary coating, and hydroxypropyl methylcellulose phthalate (HPMCP) and shellac for the secondary enteric coating. The isotherm profiles of the lactase microcapsule powders coated with HPMCP and shellac were type II and III, respectively. Compared with the shellac-coated microcapsules, the HPMCP-coated microcapsules showed lower moisture absorption (2.88% versus 38.06% of sample by weight), greater moisture desorption (0% versus 3.78% of sample by weight), and a longer predicted half-life (27.95 versus 12.25 months). Thus, the storage period of lactase was successfully elongated by microencapsulation, and HPMCP was superior to shellac as an enteric coating material for lactase microencapsulation.

Practical applications

The lactase microcpasules can be added in milk to prevent lactose intolerance. Also, the moisture sorption profile and storage period prediction of the capsules are expected to establish an efficient storage environment of the microcapsules in mass prodution and distribution of the capsules.

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