Nailfold videocapillaroscopy and serum vascular endothelial growth factor in probable COVID-19-induced chilblains: a cross-sectional study to assess microvascular impairment
Corresponding Author
Yora Mostmans
Department of Immunology and Allergology (CIA), Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Email: [email protected]Contribution: Conceptualization (lead), Data curation (lead), Formal analysis (lead), Funding acquisition (lead), Investigation (lead), Methodology (lead), Project administration (lead), Resources (lead), Software (lead), Supervision (lead), Validation (lead), Visualization (lead), Writing - original draft (lead), Writing - review & editing (lead)
Search for more papers by this authorVanessa Smith
Department of Internal Medicine, Ghent University, Ghent, Belgium
Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium
Contribution: Data curation (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (lead), Supervision (supporting), Validation (supporting), Visualization (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorMaurizio Cutolo
Research Laboratory and Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Genoa, Italy
Contribution: Data curation (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Supervision (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorKarin Melsens
Department of Internal Medicine, Ghent University, Ghent, Belgium
Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium
Contribution: Data curation (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Software (supporting), Validation (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorSalomé Battist
Department of Internalmedicine, Université Libre de Bruxelles (ULB), Route de Lennik, 808 Brussels, Belgium
Contribution: Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Software (supporting), Writing - review & editing (supporting)
Search for more papers by this authorAsma Benslimane
Department of Immunology, Laboratoire Hospitalier Universitaire deBruxelles – Universitair Laboratorium Brussels (LHUB-ULB), Route de Lennik, 808 Brussels, Belgium
Contribution: Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Resources (supporting), Writing - review & editing (supporting)
Search for more papers by this authorFrancis Corazza
Department of Immunology, Laboratoire Hospitalier Universitaire deBruxelles – Universitair Laboratorium Brussels (LHUB-ULB), Route de Lennik, 808 Brussels, Belgium
Contribution: Conceptualization (supporting), Data curation (supporting), Formal analysis (supporting), Methodology (supporting), Resources (supporting), Supervision (supporting), Validation (supporting), Writing - review & editing (supporting)
Search for more papers by this authorBertrand Richert
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Saint-Pierre, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Contribution: Conceptualization (supporting), Data curation (supporting), Formal analysis (supporting), Methodology (supporting), Resources (supporting), Supervision (supporting), Validation (supporting), Writing - review & editing (supporting)
Search for more papers by this authorOlivier Michel
Department of Immunology and Allergology (CIA), Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Contribution: Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Software (supporting), Supervision (supporting), Validation (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorAthanassios Kolivras
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Saint-Pierre, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Contribution: Conceptualization (supporting), Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Supervision (supporting), Validation (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorCorresponding Author
Yora Mostmans
Department of Immunology and Allergology (CIA), Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Email: [email protected]Contribution: Conceptualization (lead), Data curation (lead), Formal analysis (lead), Funding acquisition (lead), Investigation (lead), Methodology (lead), Project administration (lead), Resources (lead), Software (lead), Supervision (lead), Validation (lead), Visualization (lead), Writing - original draft (lead), Writing - review & editing (lead)
Search for more papers by this authorVanessa Smith
Department of Internal Medicine, Ghent University, Ghent, Belgium
Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium
Contribution: Data curation (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (lead), Supervision (supporting), Validation (supporting), Visualization (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorMaurizio Cutolo
Research Laboratory and Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Genoa, Italy
Contribution: Data curation (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Supervision (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorKarin Melsens
Department of Internal Medicine, Ghent University, Ghent, Belgium
Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium
Contribution: Data curation (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Software (supporting), Validation (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorSalomé Battist
Department of Internalmedicine, Université Libre de Bruxelles (ULB), Route de Lennik, 808 Brussels, Belgium
Contribution: Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Software (supporting), Writing - review & editing (supporting)
Search for more papers by this authorAsma Benslimane
Department of Immunology, Laboratoire Hospitalier Universitaire deBruxelles – Universitair Laboratorium Brussels (LHUB-ULB), Route de Lennik, 808 Brussels, Belgium
Contribution: Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Resources (supporting), Writing - review & editing (supporting)
Search for more papers by this authorFrancis Corazza
Department of Immunology, Laboratoire Hospitalier Universitaire deBruxelles – Universitair Laboratorium Brussels (LHUB-ULB), Route de Lennik, 808 Brussels, Belgium
Contribution: Conceptualization (supporting), Data curation (supporting), Formal analysis (supporting), Methodology (supporting), Resources (supporting), Supervision (supporting), Validation (supporting), Writing - review & editing (supporting)
Search for more papers by this authorBertrand Richert
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Saint-Pierre, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Contribution: Conceptualization (supporting), Data curation (supporting), Formal analysis (supporting), Methodology (supporting), Resources (supporting), Supervision (supporting), Validation (supporting), Writing - review & editing (supporting)
Search for more papers by this authorOlivier Michel
Department of Immunology and Allergology (CIA), Centre Hospitalier Universitaire (CHU) Brugmann, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Contribution: Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Software (supporting), Supervision (supporting), Validation (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorAthanassios Kolivras
Department of Dermatology, Centre Hospitalier Universitaire (CHU) Saint-Pierre, Université Libre de Bruxelles (ULB), Van Gehuchten plein 4, Brussels, Belgium
Contribution: Conceptualization (supporting), Data curation (supporting), Formal analysis (supporting), Investigation (supporting), Methodology (supporting), Project administration (supporting), Resources (supporting), Supervision (supporting), Validation (supporting), Writing - original draft (supporting), Writing - review & editing (supporting)
Search for more papers by this authorFunding sources: Y.M. has received a grant from The Brugmann Foundation for scientific research in chronic urticaria.
Conflicts of interest: V.S. is a Senior Clinical Investigator of the Research Foundation - Flanders (Belgium) (FWO) (1·8·029.20N). V.S. is supported by an unrestricted educational chair on systemic sclerosis of Janssen-Cilag NV. V.S. has received grant/research support from the Belgian Fund for Scientific Research in Rheumatic Diseases (FWRO) and Boehringer-Ingelheim Pharma GmbH; consulting fees were provided by Boehringer-Ingelheim GmbH and Janssen-Cilag NV; speaker fees were provided by UCB Biopharma Sprl, Boehringer-Ingelheim GmbH, Janssen-Cilag NV and Actelion Pharmaceuticals.
Data availability: the data that support the findings of this study are available from the corresponding author upon reasonable request.
Ethics statement: this study has been approved by Le Comité d’Ethique of CHU Saint-Pierre (registration number CE/20-04-19).
References
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