Review
Optical Fiber Optofluidic Bio-Chemical Sensors: A Review
Like Li,
Ya-nan Zhang,
Yifan Zhou,
Wanlu Zheng,
Yutong Sun,
Guoming Ma,
Yong Zhao,
Like Li
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorCorresponding Author
Ya-nan Zhang
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology, Qinhuangdao, 066004 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
E-mail: [email protected]
Search for more papers by this authorYifan Zhou
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorWanlu Zheng
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorYutong Sun
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorGuoming Ma
State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources (North China Electric Power University)
Search for more papers by this authorYong Zhao
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology, Qinhuangdao, 066004 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorLike Li,
Ya-nan Zhang,
Yifan Zhou,
Wanlu Zheng,
Yutong Sun,
Guoming Ma,
Yong Zhao,
Like Li
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorCorresponding Author
Ya-nan Zhang
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology, Qinhuangdao, 066004 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
E-mail: [email protected]
Search for more papers by this authorYifan Zhou
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorWanlu Zheng
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorYutong Sun
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorGuoming Ma
State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources (North China Electric Power University)
Search for more papers by this authorYong Zhao
State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819 China
Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology, Qinhuangdao, 066004 China
College of Information Science and Engineering, Northeastern University, Shenyang, 110819 China
Search for more papers by this authorAbstract
Optofluidic, as an emerging technology that combines photons and microfluidics, has become a powerful, intelligent, and universal sensing platform in the field of bio-chemical sensing. Optical fiber optofluidic (OFOF), as a branch of optofluidic technology, has stimulated a host of remarkable achievements in the field of bio-chemical sensing due to its superiority of compact structure, immunity to electromagnetic interference, low sample consumption, high sensitivity, and real-time dynamic response. In this paper, an overview of OFOF bio-chemical sensors is presented. The OFOF system architectures are introduced and some advanced functional materials and coating technologies that can be utilized in the OFOF sensing platform to achieve high-performance biochemical sensing are summarized. Research progress and current status of OFOF bio-chemical sensors based on various sensing mechanisms are summarized and analyzed, with emphases on their sensing principles, sensing structures, sensing applications, advantages, and disadvantages. Lastly, the existing challenges and future development trends of OFOF biochemical sensors are briefly discussed.
Conflict of Interest
The authors declare no conflict of interest.
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