CORRESPONDENCE
Letter to the editor: Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury
Zhuqing Rao,
Zhuqing Rao
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Search for more papers by this author Fei Li,
Fei Li
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Search for more papers by this author Zhu Guan,
Zhu Guan
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Search for more papers by this author Haoming Zhou,
Corresponding Author
Haoming Zhou
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Correspondence
Haoming Zhou, Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China.
Email: [email protected]
Search for more papers by this author
Zhuqing Rao,
Zhuqing Rao
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Search for more papers by this author Fei Li,
Fei Li
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Search for more papers by this author Zhu Guan,
Zhu Guan
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Search for more papers by this author Haoming Zhou,
Corresponding Author
Haoming Zhou
Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Correspondence
Haoming Zhou, Department of Anesthesiology, Hepatobiliary/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China.
Email: [email protected]
Search for more papers by this author
First published: 16 April 2022
No abstract is available for this article.
REFERENCES
- 1Chen LI, Dong J, Liao S, Wang S, Wu Z, Zuo M, et al. Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury. Hepatology. 2022. https://doi.org/10.1002/hep.32471
- 2Yu Y, Liu Y, An W, Song J, Zhang Y, Zhao X. STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis. J Clin Invest. 2019; 129: 546–55.
- 3Chen S, Chen J, Hua X, Sun Y, Cui R, Sha J, et al. The emerging role of XBP1 in cancer. Biomed Pharmacother. 2020; 127:110069.
- 4Liu Z, Wang M, Wang X, Bu Q, Wang QI, Su W, et al. XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA–cGAS–STING signaling in macrophages during acute liver injury. Redox Biol. 2022. https://doi.org/10.1016/j.redox.2022.102305
- 5Scherz-Shouval R, Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends Biochem Sci. 2011; 36: 30–8.