Concise Report
1,3-Dipolar Cycloaddition of Polycyclic Aromatic Azomethine Ylides and Alkynylbenziodoxoles for Synthesis of Functional Dibenzoullazines†
Hui Han,
Glen Wee Zhuan Goh,
Yongxin Li,
Naohiko Yoshikai,
Shingo Ito,
Hui Han
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
Search for more papers by this authorGlen Wee Zhuan Goh
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
Search for more papers by this authorYongxin Li
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
Search for more papers by this authorNaohiko Yoshikai
Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578 Japan
Search for more papers by this authorCorresponding Author
Shingo Ito
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
E-mail: [email protected]Search for more papers by this authorHui Han,
Glen Wee Zhuan Goh,
Yongxin Li,
Naohiko Yoshikai,
Shingo Ito,
Hui Han
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
Search for more papers by this authorGlen Wee Zhuan Goh
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
Search for more papers by this authorYongxin Li
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
Search for more papers by this authorNaohiko Yoshikai
Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578 Japan
Search for more papers by this authorCorresponding Author
Shingo Ito
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371 Singapore
E-mail: [email protected]Search for more papers by this author†
Dedicated to the Special Issue of Emerging Investigators in 2023.
Comprehensive Summary
A new family of dibenzoullazine derivatives was synthesized through 1,3-dipolar cycloaddition of polycyclic aromatic azomethine ylides with alkynylbenziodoxoles followed by oxidation. The benziodoxole moiety in the resulting products was used as a versatile linchpin for the synthesis of structurally diverse functional dibenzoullazines that are difficult to access by other synthetic methods.
Supporting Information
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| cjoc202300637-sup-0001-supinfo.pdfPDF document, 3.8 MB |
Appendix S1: Supporting Information |
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