Concise Report
Copper-Catalyzed [3 + 2 + 1] Cycloaddition of Alkenes with Benzoquinones and Dicarbonyl Compounds via Tandem Oxidative Dicarbofunctionalization/Cyclization Sequence
Tianxing Du,
Song Li,
Yunfei He,
Huan Long,
Xigong Liu,
Hai-Bei Li,
Lei Liu,
Tianxing Du
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
Search for more papers by this authorSong Li
School of Ocean, Shandong University, Weihai, Shandong, 264209 China
Search for more papers by this authorYunfei He
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
Search for more papers by this authorHuan Long
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
Search for more papers by this authorCorresponding Author
Xigong Liu
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
E-mail: [email protected]; [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Hai-Bei Li
School of Ocean, Shandong University, Weihai, Shandong, 264209 China
E-mail: [email protected]; [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Lei Liu
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
E-mail: [email protected]; [email protected]; [email protected]Search for more papers by this authorTianxing Du,
Song Li,
Yunfei He,
Huan Long,
Xigong Liu,
Hai-Bei Li,
Lei Liu,
Tianxing Du
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
Search for more papers by this authorSong Li
School of Ocean, Shandong University, Weihai, Shandong, 264209 China
Search for more papers by this authorYunfei He
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
Search for more papers by this authorHuan Long
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
Search for more papers by this authorCorresponding Author
Xigong Liu
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
E-mail: [email protected]; [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Hai-Bei Li
School of Ocean, Shandong University, Weihai, Shandong, 264209 China
E-mail: [email protected]; [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Lei Liu
School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong, 250100 China
E-mail: [email protected]; [email protected]; [email protected]Search for more papers by this authorComprehensive Summary
Developed is an efficient three-component [3 + 2 + 1] cycloaddition of simple alkenes with two C—H substrates via oxidative dicarbofunctionalization/cyclization sequence. The copper-catalyzed reaction involves the formation of two C—C bonds and one C—O bond through the cleavage of three C—H bonds in a single operation. The method has an excellent functional group tolerance, and features a broad substrate scope, affording a variety of functionalized chromenes in good yields.
Supporting Information
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