Highly Efficient Synthesis of Arylpyrrole Derivatives via Rh(III)-Catalyzed Direct CH Arylation with Aryl Boronic Acids
Corresponding Author
Liang Wang
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
School of Chemical and Enviromental Engineering, Jianghan University, Wuhan, Hubei 430056, China
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, ChinaSearch for more papers by this authorZhan Li
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
Search for more papers by this authorXing Qu
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
Search for more papers by this authorCorresponding Author
Wangming Peng
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, ChinaSearch for more papers by this authorCorresponding Author
Liang Wang
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
School of Chemical and Enviromental Engineering, Jianghan University, Wuhan, Hubei 430056, China
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, ChinaSearch for more papers by this authorZhan Li
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
Search for more papers by this authorXing Qu
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
Search for more papers by this authorCorresponding Author
Wangming Peng
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, China
Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, Jianghan University, Wuhan, Hubei 430056, ChinaSearch for more papers by this authorAbstract
An efficient and facile method for synthesis of 2-arylpyrroles through Rh(III)-catalyzed direct CH arylation with pyrrole derivatives and aryl boronic acids has been developed. This reaction could proceed under mild reaction conditions and afford a series of 2-arylated products in good to excellent yields. The gram-scale experiment has been conducted to demonstrate the synthetic potential of this methodology.
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