Review
Circadian Rhythms and the Transcriptional Feedback Loop (Nobel Lecture)**
Michael Rosbash,
Corresponding Author
Michael Rosbash
Department of Biology, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA
Search for more papers by this authorMichael Rosbash,
Corresponding Author
Michael Rosbash
Department of Biology, Howard Hughes Medical Institute, Brandeis University, Waltham, MA, USA
Search for more papers by this author**
Copyright© The Nobel Foundation 2017. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.
Graphical Abstract
Circadian rhythms are present in most if not all animals, plants, and even photosynthetic cyanobacteria. These cyanobacterial clocks as well as plant clocks are very different from those of animals, with no credible homology between the different clock proteins. Therefore circadian rhythms probably emerged multiple times in evolution, which underscores their importance.
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