Cover Picture: Total Synthesis of Paliurine F (Angew. Chem. Int. Ed. 4/2007)
Abstract
The sedative paliurine F, which was isolated from the roots of Paliurus ramossisimus, is part of a huge family of natural products that display interesting biological effects and possess an especially appealing and challenging macrocyclic structure. In their Communication on page 572 ff., G. Evano and co-workers describe the synthesis of one of these cyclopeptide alkaloids, paliurine F, using a route that showcases the recent advances in copper(I)-mediated coupling reactions.
