Transient Helicity: Fuel-Driven Temporal Control over Conformational Switching in a Supramolecular Polymer
Shikha Dhiman
Supramolecular Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064 India
Search for more papers by this authorAnkit Jain
Supramolecular Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064 India
Search for more papers by this authorCorresponding Author
Prof. Subi J. George
Supramolecular Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064 India
Search for more papers by this authorShikha Dhiman
Supramolecular Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064 India
Search for more papers by this authorAnkit Jain
Supramolecular Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064 India
Search for more papers by this authorCorresponding Author
Prof. Subi J. George
Supramolecular Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur, Bangalore, 560064 India
Search for more papers by this authorAbstract
Synthetic manifestations of supramolecular chirality have extensively drawn inspiration from naturally occurring systems. Even though in biological systems conformational changes are dissipative, synthetic systems that change conformation under non-equilibrium conditions have still not been established. Herein, we attempt to alleviate this scenario by reporting a synthetic supramolecular system that undergoes temporal changes in its helical conformation as an active system at the expense of a biologically relevant chemical fuel, ATP. Use of enzymes working in tandem provides transient and switchable helices with modular lifetime and stereomutation rates.
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References
- 1
- 1aE. D. Korn, Physiol. Rev. 1982, 62, 672–737;
- 1bT. Mitchison, M. Kirschner, Nature 1984, 312, 237–242.
- 2T. Hayashi, S. Chiba, Y. Kaneta, T. Furuta, M. Sakurai, J. Phys. Chem. B 2014, 118, 12612–12620.
- 3
- 3aB. A. Grzybowski, W. T. S. Huck, Nat. Nanotechnol. 2016, 11, 585–592;
- 3bE. Mattia, S. Otto, Nat. Nanotechnol. 2015, 10, 111–119;
- 3cJ.-F. Lutz, J.-M. Lehn, E. W. Meijer, K. Matyjaszewski, Nat. Rev. Mater. 2016, 1, 16024.
- 4
- 4aJ. Boekhoven, A. M. Brizard, K. N. K. Kowlgi, G. J. M. Koper, R. Eelkema, J. H. van Esch, Angew. Chem. Int. Ed. 2010, 49, 4825–4828; Angew. Chem. 2010, 122, 4935–4938;
- 4bJ. Boekhoven, J. M. Poolman, C. Maity, F. Li, L. van der Mee, C. B. Minkenberg, E. Mendes, J. H. van Esch, R. Eelkema, Nat. Chem. 2013, 5, 433–437;
- 4cS. Debnath, S. Roy, R. V. Ulijn, J. Am. Chem. Soc. 2013, 135, 16789–16792;
- 4dH. Thomas, A.-K. Steppert, C. M. Lopez, B. Zhu, A. Walther, Nano Lett. 2014, 15, 2213–2219;
- 4eC. G. Pappas, I. R. Sesselli, R. V. Ulijn, Angew. Chem. Int. Ed. 2015, 54, 8119–8123; Angew. Chem. 2015, 127, 8237–8241;
- 4fS. K. M. Nalluri, C. Berdugo, N. Javid, P. W. J. M. Frederix, R. V. Ulijn, Angew. Chem. Int. Ed. 2014, 53, 5882–5887; Angew. Chem. 2014, 126, 5992–5997;
- 4gJ. K. Sahoo, S. K. M. Nalluri, N. Javid, H. Webba, R. V. Ulijn, Chem. Commun. 2014, 50, 5462–5464;
- 4hT. Heuser, E. Weyandt, A. Walther, Angew. Chem. Int. Ed. 2015, 54, 13258–13262; Angew. Chem. 2015, 127, 13456–13460;
- 4iJ. Boekhoven, W. E. Hendriksen, G. J. M. Koper, R. Eelkema, J. H. van Esch, Science 2015, 349, 1075–1079.
- 5
- 5aC. Pezzato, L. J. Prins, Nat. Commun. 2015, 6, 7790;
- 5bS. Maiti, I. Fortunati, C. Ferrante, P. Scrimin, L. J. Prins, Nat. Chem. 2016, 8, 725–781.
- 6
- 6aS. Sakurai, K. Okoshi, J. Kumaki, E. Yashima, J. Am. Chem. Soc. 2006, 128, 5650–5651;
- 6bA. R. A. Palmans, E. W. Meijer, Angew. Chem. Int. Ed. 2007, 46, 8948–8968; Angew. Chem. 2007, 119, 9106–9126;
- 6cJ. Cho, M. Tanaka, S. Sato, K. Kinbara, T. Aida, J. Am. Chem. Soc. 2010, 132, 13176–13178;
- 6dN. Ousaka, Y. Takeyama, E. Yashima, Chem. Eur. J. 2013, 19, 4680–4685;
- 6eJ. Kang, D. Miyajima, Y. Itoh, T. Mori, H. Tanaka, M. Yamauchi, Y. Inoue, S. Harada, T. Aida, J. Am. Chem. Soc. 2014, 136, 10640–10644;
- 6fM. Yamauchi, T. Ohba, T. Karatsu, S. Yagai, Nat. Commun. 2015, 6, 8936;
- 6gM. Kumar, M. D. Reddy, A. Mishra, S. J. George, Org. Biomol. Chem. 2015, 13, 9938–9942;
- 6hM. Vlatković, B. L. Feringa, S. J. Wezenberg, Angew. Chem. Int. Ed. 2016, 55, 1001–1004; Angew. Chem. 2016, 128, 1013–1016;
- 6iH. K. Bisoyi, Q. Li, Angew. Chem. Int. Ed. 2016, 55, 2994–3010; Angew. Chem. 2016, 128, 3046–3063.
- 7
- 7aM. Kumar, S. J. George, Chem. Commun. 2012, 48, 10948–10950;
- 7bM. Kumar, P. Brocorens, C. Tonnelé, D. Beljonne, M. Surin, S. J. George, Nat. Commun. 2014, 6, 5793;
- 7cM. Kumar, S. J. George, Chem. Sci. 2014, 5, 3025–3030.
- 8
- 8aA. Ojida, S.-K. Park, Y. Mito-oka, I. Hamachi, Tetrahedron Lett. 2002, 43, 6193–6195;
- 8bO. Akio, Y. Mito-oka, K. Sada, I. Hamachi, J. Am. Chem. Soc. 2004, 126, 2454–2463.
- 9A. Sols, R. K. Crane, J. Biol. Chem. 1954, 210, 597–606.
- 10A. Desmarchelier, X. Caumes, M. Raynal, A. Vidal-Ferran, P. W. N. M. van Leeuwen, L. Bouteiller, J. Am. Chem. Soc. 2016, 138, 4908–4916.
- 11
- 11aY. Shoji, K. Tashiro, T. Aida, J. Am. Chem. Soc. 2010, 132, 5928–5929;
- 11bK. Shimomura, T. Ikai, S. Kanoh, E. Yashima, K. Maeda, Nat. Chem. 2014, 6, 429–434;
- 11cE. Yashima, N. Ousaka, D. Taura, K. Shimomura, T. Ikai, K. Maeda, Chem. Rev. 2016, 116, 13752–13990.
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