Gold-Catalyzed Intermolecular CS Bond Formation: Efficient Synthesis of α-Substituted Vinyl Sulfones†
Yumeng Xi
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorBoliang Dong
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorEdward J. McClain
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorQiaoyi Wang
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorTesia L. Gregg
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorDr. Novruz G. Akhmedov
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorProf. Jeffrey L. Petersen
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorCorresponding Author
Prof. Xiaodong Shi
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/===Search for more papers by this authorYumeng Xi
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorBoliang Dong
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorEdward J. McClain
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorQiaoyi Wang
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorTesia L. Gregg
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorDr. Novruz G. Akhmedov
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorProf. Jeffrey L. Petersen
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
Search for more papers by this authorCorresponding Author
Prof. Xiaodong Shi
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/
C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV 26506 (USA) http://community.wvu.edu/∼xs007/===Search for more papers by this authorWe are grateful to the NSF (CAREER-CHE-0844602 and CHE-1228336) and the NSFC (21228204) for financial support.
Abstract
A general method for the synthesis of α-substituted vinyl sulfones makes use of a combination of a triazole gold complex and gallium triflate. This efficient CS bond formation between simple terminal alkynes and sulfinic acids provides access to various α-substituted vinyl sulfones.
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