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Implementation of a Multi-Gene Molecular Panel at Fine Needle Aspiration Biopsy (FNAB) Thyroid Samples: A Compelling Diagnostic and Prognostic Model

Angeliki Margoni

Angeliki Margoni

Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece

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Kostas A. Papavassiliou

Kostas A. Papavassiliou

First University Department of Respiratory Medicine, ‘Sotiria’ Chest Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

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Athanasios G. Papavassiliou

Corresponding Author

Athanasios G. Papavassiliou

Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece

Correspondence:

Athanasios G. Papavassiliou ([email protected])

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First published: 18 June 2025

Funding: The authors received no specific funding for this work.

Abstract

Application of a multi-gene panel in FNAB thyroid samples provides a patient-directed diagnostic and prognostic model. Several genetic mutations and molecular markers are correlated with histological subtypes of thyroid cancer, revealing the potential role of molecular techniques in targeted therapy. The combination of FNAB and multi-gene tests introduces clinicians to the benefits of precision oncology.

Data Availability Statement

The authors have nothing to report.

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