Volume 11, Issue 1 pp. 90-92
Research Letter

Expression of inflammasome complex mRNA and its targeted microRNA in type 2 diabetes mellitus: A possible predictor of the severity of diabetic nephropathy

在2型糖尿病患者中炎症体复合物mRNA及其靶向微小RNA的表达:一种有可能预测糖尿病肾病严重程度的因子

Chandra K. Bhattacharjee

Chandra K. Bhattacharjee

Department of Epidemiology and Nutrition, Indian Council of Medical Research – Regional Medical Research Centre North Easter Region, Dibrugarh, India

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Suman K. Paine

Suman K. Paine

Department of Epidemiology and Nutrition, Indian Council of Medical Research – Regional Medical Research Centre North Easter Region, Dibrugarh, India

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Jagadish Mahanta

Jagadish Mahanta

Department of Epidemiology and Nutrition, Indian Council of Medical Research – Regional Medical Research Centre North Easter Region, Dibrugarh, India

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Sawjib Borphukan

Sawjib Borphukan

Department of Nephrology, Assam Medical College and Hospital, Dibrugarh, India

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Prasanta K. Borah

Corresponding Author

Prasanta K. Borah

Department of Epidemiology and Nutrition, Indian Council of Medical Research – Regional Medical Research Centre North Easter Region, Dibrugarh, India

Correspondence

Prasanta K. Borah, Indian Council of Medical Research – Regional Medical Research Centre, North Eastern Region, Dibrugarh 786001, Assam, India.

Email: [email protected]

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First published: 26 August 2018
Citations: 5

Abstract

Highlights

  • Concomitant elevated expression of Caspase-1 in respect of reduced eGFR among DN may serve as better explainable marker for the adverse prognosis of the disease
  • Study may open new horizon to understand patho-mechanism with the aid of Inflammasome-complex.

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