Volume 6, Issue 3 e70043
COVER PICTURE
Open Access

Cover Picture: Semaglutide to remodel mitochondrial dynamics and mitophagy balance for vascular dementia therapy (View 3/2025)

First published: 18 June 2025

Graphical Abstract

Semaglutide maintained the balance of mitochondrial dynamics and mitophagy by improving insulin resistance and passing through GLP-1R/PI3K/Akt pathway, reduced hippocampal neuroinflammation and neuron loss, and thus promoted the recovery of cognitive function in bilateral common carotid artery stenosis (BCAS) mouse model of VaD.

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