In this review article, we focus on recent papers on the organ-preserving pancreatectomies that have been published since 2010.

Antiadhesion membrane did not decrease small bowel obstruction occurrence rate after open gastrectomy. Therefore, the use of antiadhesion membrane would not be effective for preventing SBO in gastric cancer surgery.

This study performed a propensity score matching analysis using cases from a large-scale, multicenter, phase III randomized controlled trial concerning oral nutritional supplements after gastrectomy and analyzed both the whole cohort and matched cohort. Measurements of body composition and handgrip strength were performed after gastrectomy. Loss of skeletal muscle mass was significantly lesser in the laparoscopic gastrectomy group than in the open gastrectomy group in both cohorts.

This study retrospectively analyzed duodenal cancer (DC) patients who underwent surgical resection, categorizing lymph node (LN) stations into Np (upstream) and Nd (other) based on lymphatic flow. It was found that patients with lymph node metastasis (LNM) in the Nd stations had significantly worse survival rates than those with LNM only in the Np stations, with multivariate analysis identifying LNM in Nd stations as an independent prognostic factor. The study concluded that while dissection of Np stations led to acceptable survival, LNM of Nd stations resulted in poor survival, potentially indicating advanced systemic disease progression in DC patients.

The present study investigated he clinical course and long-term outcomes of 97 gastric cancer patients with oligometastasis. The patients with oligometastasis had a favorable prognosis, with a median survival time of 22.8 months and a 5-year overall survival rate of 28.4%. On multivariate analysis, chemotherapy for the initial treatment, distal gastrectomy and/or metastasectomy, and R0 resection were identified as independent, positive factors of overall survival.

We report the short/mid-term results of surgery for high-risk locally advanced rectal cancer (LARC) after neoadjuvant chemotherapy (NAC, four courses of S-1 + oxaliplatin+ bevacizumab) without radiotherapy with the primary aim of ypT0-2. NAC yielded a clinically significant effect in about half of high-risk LARC patients.

This was a prospective, open-label, single-arm phase II trial, which evaluated the safety of robotic surgery for right-sided colon cancer in Japan. This study demonstrated the safety and feasibility of robotic surgery for right-sided colon cancer.

Overall survival curves after CRS for synchronous and metachronous peritoneal dissemination group.

A high extracellular water to total body water ratio, which reflects malnutrition and systemic inflammation, is an independent predictive factor for recurrence and poor overall survival in patients with colorectal cancer who underwent potentially curative resection.

The impact of the COVID-19 pandemic on short-term outcomes following rectal cancer surgery was minimal in Japan despite a temporary decrease in the ICU admission rate. This is the first study examining the impact of COVID-19 on postoperative complications following rectal cancer surgery using national big data from Japan.

This cross-sectional survey study has investigated the incidence and risk factors of low anterior resection syndrome (LARS) as well as evaluated its association with QOL in Japanese patients. The incidence of major LARS is 22%, and independent risk factors include lower tumors and surgical procedures with lower anastomoses. More severe LARS is associated with worse QOL which is significantly more impaired in patients with lower tumors.

The CY-positive rates, CY-negative conversion rates, and conversion surgery rates varied according to local progression. In the case of R and BR-PDAC, staging laparoscopy could be considered in patients with pancreatic body or tail carcinoma, large tumor size, or high DUPAN-2 level. In UR-LA, staging laparoscopy might be considered for all patients.

This study investigated the trends in survival outcomes of patients with HCV-associated HCC who underwent hepatectomy before and after the introduction of DAA therapy at a tertiary referral center for hepatobiliary surgery. We found that survival outcomes were not changed before and after introduction of DAA therapy. Although some papers emphasize the “oncologic” benefit of DAA therapy, its effect was skeptical based on this study.

We evaluated long-term outcomes in our patients by CAR-mALBI score. We have shown CAR-mALBI score is associated with disease-free and overall survival.

The total neoadjuvant strategy for patients with borderline resectable pancreatic cancer with arterial involvement improved the prognosis compared with upfront surgery or neoadjuvant chemoradiotherapy. Total neoadjuvant therapy can be a promising therapeutic strategy.

mTOR expression is high in patients with hepatocellular carcinoma (HCC) that have vessels that encapsulate tumor clusters, suggesting that the mTOR inhibitor, everolimus, could be particularly affective in patients with HCC being treated using living donor liver transplantation.