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ISSUE INFORMATION
ORIGINAL ARTICLE
Demonstration of autonomous fixed-wing drone delivery of prescribed medications in remote islands in Japan
- Pages: 195-204
- First Published: 09 January 2025

We demonstrated a combination of online medication counseling and drone delivery of medications dispensed by pharmacists in two rural clinics located far from pharmacies on remote islands in Japan. After being prescribed by physicians, dispensed by pharmacists, and online medication counseling, the medications were transported by autonomous fixed-wing drones, dropped, and picked up by the staff.
Factors associated with hypertonic dehydration in older Japanese outpatients
- Pages: 205-212
- First Published: 10 January 2025

The purpose of this study is to statistically identify the risk factors for hypertonic dehydration among older population in Japan. This cross-sectional study included outpatients aged ≥65 years who visited an internal medicine clinic. Decreased fluid intake, obesity, diabetes mellitus, and polypharmacy were independently associated with hypertonic dehydration in older Japanese outpatients.
Withdrawal of life-sustaining treatment in Japanese home care: A cross-sectional survey
- Pages: 213-221
- First Published: 14 January 2025
Spinal amyloid deposits are common among older patients undergoing spinal stenosis decompression surgery
- Pages: 222-230
- First Published: 15 January 2025

In this report, we demonstrate that spinal stenosis is associated with amyloid deposits in the spine. We further demonstrate that amyloid deposits are present not only in the ligamentum flavum but also in the disc tissue. We subsequently examined patients for transthyretin amyloid cardiomyopathy and found no evidence in patients tested.
Do family physicians develop ambiguity tolerance as they gain experience? A multicenter cross-sectional study
- Pages: 231-237
- First Published: 03 February 2025
Predicting 30-day mortality in older patients with suspected infections by adding performance status to quick sequential organ failure assessment
- Pages: 238-245
- First Published: 05 February 2025
The extended model (ECOG-PS + qSOFA) significantly improved discrimination in predicting mortality among older patients with suspected infections compared to the model with qSOFA alone (p = 0.008), with the net reclassification index revealing that 21 (17.5%) of the deceased were elevated to a higher risk category. This approach integrates routinely measured functional measures for enhanced risk assessment.
An observational study to determine the optimal physical evaluation site for detecting anemia
- Pages: 246-254
- First Published: 14 February 2025
“The future”: Interpretative phenomenological analysis of general practitioners' experiences of co-employed clinical psychologists
- Pages: 255-262
- First Published: 24 February 2025
CASE REPORT
Extreme hypercalcemia secondary to parathyroid adenoma obscured by excessive coffee consumption and premature ventricular complexes
- Pages: 263-266
- First Published: 14 February 2025
CLINICAL IMAGE
Cervical epidural abscess mimicking crowned dens syndrome
- Pages: 267-268
- First Published: 06 February 2025
PRELIMINARY REPORT
Addressing healthcare needs in an inaugural family medicine clinic in a core city in Japan: Mixed-methods research
- Pages: 269-272
- First Published: 21 March 2025
LETTER TO THE EDITOR
Erosive and annular lesions of the gastric mucosa: Not negligible signs of Treponema pallidum infection
- Pages: 273-274
- First Published: 03 February 2025
Developing sustainable generalism education in community settings: Insights from the JPCA (Japan Primary Care Association) Conference, 2024
- Pages: 275-276
- First Published: 10 January 2025