The synthesis of functionalized (trichloromethyl)quinazoline-4(1H)-one through a novel intramolecular CH activation reaction from trichloroacetonitrile, benzoyl chlorides, and various primary amines is a remarkable achievement in organic chemistry. Furthermore, the product with phenylacetylene and sodium azide in the presence of a copper catalyst in water solvent at room temperature demonstrates a new (1,2,3-triazole)-quinazoline-4(1H)-one derivative.

Herein, we describe a formal [3 + 3] cycloaddition of 4-hydroxycoumarins with propargylicalcohols catalyzed by benzenediazonium tetrafluoroborate as the Lewis acid catalyst for the synthesis of pyranocoumarins under mild conditions.

The interaction of perfluoro-1,4-naphthoquinone with various 5-aminopyrazoles.

An efficient access to novel families of 7-membered dibenzodiazepines and 6-membered benzo[c]cinnoline derivatives has been elaborated. The synthetic strategy is based on a copper-catalyzed double N-arylation of cyclic diaryliodoniums with imidamides and 4-substituted 1, 2, 4-triazoline-3, 5-diones (TADs) respectively under ambient reaction conditions. A mechanistic rationale for the double N-arylation is discussed.

[3+2]-cycloaddition/esterification cascade of donor-acceptor cyclopropanes with salicylaldehydes for the synthesis of tetrahydro-4H-furo[3,2-c]chromen-4-ones

Synthesis, X-ray characterization and anticancer evaluation of new derivatives of sulfadiazine

Five new benzannulated steroid spiroketals were synthesized by Pd-catalyzed spiroketalization of 5α and 5β-alkynediols derived from stigmasterol and sitosterol. The detailed NMR and X-ray characterization of the newly obtained spiroketals are presented. While the obtained compounds showed null or very low cytotoxicity, two of them inhibited more than 60% of the nitrous oxide production in J774A.1 macrophages stimulated with LPS, showing promising properties as anti-inflammatory agents.

1,5-Diazocine-based diaryl ketones as hosts for PhOLEDs whereby electroluminescence was tuned by maneuvering twisting in these hosts.

Visible light mediated synthesis of carbamates and carbonates through carbon dioxide (CO₂) fixation using photocatalysts. Carbamates and carbonates are profitable and fascinating compounds for industrial applications where CO₂ has been incorporated as a C1-synthon thus also serving in minimizing the harmful impact of CO₂.

This review summarizes microwave synthesis methods for coumarin derivatives, including the Perkin, Knoevenagel, Pechmann, Kostanecki-Robinson, and Reformansky reactions, as well as their biological activities.

An efficient [4+2] annulation reaction of o-acylamino-aryl Morita-Baylis-Hillman carbonates with isatylidene malononitriles is reported. Under mild conditions, we have successfully obtained a series of underreported spiro[indolin-3,2′-quinoline] framework compounds.