• Issue

    International Journal of Developmental Neuroscience: Volume 82, Issue 4

    287-371
    June 2022

ISSUE INFORMATION

Free Access

Issue Information

  • Pages: 287-288
  • First Published: 02 June 2022

REVIEW ARTICLE

Novel findings, mini-review and dysmorphological characterization of 16p13.11 microduplication syndrome

  • Pages: 289-294
  • First Published: 26 April 2022

16p13.11 microduplications are rare, with no established clinical consensus in regard with its clinical picture, including its dysmorphology. A 5-year-and-2-month-old 16p13.11 microduplication patient with epilepsy, autism and late speech onset, who additionally had unilateral preauricular skin tag and upslanting palpebral fissures findings is discussed. The recurrent dysmorphological findings in the literature, along with new ones are detailed, to possibly enable a characterization.

RESEARCH ARTICLES

How aerobic exercise improves executive function in ADHD children: A resting-state fMRI study

  • Pages: 295-302
  • First Published: 10 March 2022
How aerobic exercise improves executive function in ADHD children: A resting-state fMRI study

Aerobic exercise can improve the executive function of ADHD children, and the brain mechanism involved is mainly related to the enhancement of spontaneous prefrontal lobe activity.

Post-weaning exposure to Sunset Yellow FCF induces behavioral impairment and structural changes in the adult rat medial prefrontal cortex: Protective effects of Coenzyme Q10

  • Pages: 303-313
  • First Published: 16 March 2022
Post-weaning exposure to Sunset Yellow FCF induces behavioral impairment and structural changes in the adult rat medial prefrontal cortex: Protective effects of Coenzyme Q10

Sunset Yellow FCF reduced anterior cingulate cortex volume, decreased neural and glial cell count and impaired spatial memory of rats. Co-treatment with CoQ10 prevented the neural and glial cell loss, improved anxiety-like behaviours and protected against memory impairment.

The relationship between acoustic and musical pitch processing in adolescents

  • Pages: 314-330
  • First Published: 26 March 2022
The relationship between acoustic and musical pitch processing in adolescents

Amusia is associated with deficits in both acoustic and musical pitch discrimination. Early identification of amusia could lead to improved treatment possibilities. Here, we demonstrate that there is a double dissociation between abnormal acoustic pitch discrimination and abnormal musical pitch discrimination in adolescents. These results suggest that acoustic pitch discrimination should not be used in isolation to identify cases of amusia in children.

Protective effect of Celastrus paniculatus on cognitive function in glutamate-induced brain-injured mice by reducing the intracellular influx of Ca+

  • Pages: 331-338
  • First Published: 26 March 2022
Protective effect of Celastrus paniculatus on cognitive function in glutamate-induced brain-injured mice by reducing the intracellular influx of Ca+

Celastrus paniculatus attenuates neurodegeneration in glutamate induced excitotoxicity by reducing oxidative stress and inflammatory cytokines, which decreases intracellular calcium level and neuronal apoptosis.

Echinacoside alleviates sevoflurane-induced cognitive dysfunction by activating FOXO1-mediated autophagy

  • Pages: 339-348
  • First Published: 01 April 2022
Echinacoside alleviates sevoflurane-induced cognitive dysfunction by activating FOXO1-mediated autophagy

Echinacoside attenuates sevoflurane-induced cognitive impairments in mice through FOXO1-mediated autophagy.

Clinical features and prognostic analysis of posterior reversible encephalopathy syndrome in children

  • Pages: 349-360
  • First Published: 04 April 2022
Clinical features and prognostic analysis of posterior reversible encephalopathy syndrome in children

The study enrolled 47 patients with a mean age at diagnosis of 8.79±3.72 years. PRES is a clinical radiographic syndrome with multiple etiologies, which included renal disorder, hematological disease, and hypertension. PRES manifested as seizure, headache, visual impairment, dizziness, vomiting, and behavioral abnormalities. MRI mainly involved the parietal and occipital lobes. Most patients have a good prognosis. Severity on MRI and length of in-hospital stay are independent risk factors.