• Issue

    Hepatology Research: Volume 49, Issue 1

    1-119
    January 2019
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Issue Information

Free Access

Issue Information

  • Pages: 1-2
  • First Published: 15 January 2019

Review Articles

Epigenetic dysregulation in hepatocellular carcinoma: an up-to-date review

Masato Nakamura,  Tetsuhiro Chiba,  Kengo Kanayama,  Hiroaki Kanzaki,  Tomoko Saito,  Yuko Kusakabe,  Naoya Kato, 
  • Pages: 3-13
  • First Published: 20 September 2018

Recent advances in medical management of hepatocellular carcinoma

Kenji Ikeda, 
  • Pages: 14-32
  • First Published: 11 October 2018

Original Articles

Non-invasive liver fibrosis assessment correlates with collagen and elastic fiber quantity in patients with hepatitis C virus infection

Yutaka Yasui,  Tokiya Abe,  Masayuki Kurosaki,  Kotaro Matsunaga,  Mayu Higuchi,  Nobuharu Tamaki,  Keiya Watakabe,  Mao Okada,  Wan Wang,  Takao Shimizu,  Kenta Takaura,  Yohei Masugi,  Hiroyuki Nakanishi,  Kaoru Tsuchiya,  Yuka Takahashi,  Jun Itakura,  Urara Sakurai,  Akinori Hashiguchi,  Michiie Sakamoto,  Namiki Izumi, 
  • Pages: 33-41
  • First Published: 12 November 2018

Prognostic utility of novel biomarkers in acute-on-chronic liver failure (ACLF) associated with hepatitis B: A multicenter prospective study

Ruihong Zhao,  Wei Wu,  Zhibo Zhou,  Xiaoqing Zheng,  Wenjie Sun,  Yemin Shi,  Haiying Yu,  Fang Wang,  Hong Zhao,  Shanshan Sun,  Linfeng Jin,  Jifang Sheng,  Yu Shi, 
  • Pages: 42-50
  • First Published: 24 September 2018

Hepatitis B virus (HBV)-infected patients with low hepatitis B surface antigen and high hepatitis B core-related antigen titers have a high risk of HBV-related hepatocellular carcinoma

Yuichiro Suzuki,  Shinya Maekawa,  Nobutoshi Komatsu,  Mitsuaki Sato,  Akihisa Tatsumi,  Mika Miura,  Shuya Matsuda,  Masaru Muraoka,  Natsuko Nakakuki,  Hiroko Shindo,  Fumitake Amemiya,  Shinichi Takano,  Mitsuharu Fukasawa,  Yasuhiro Nakayama,  Tatsuya Yamaguchi,  Taisuke Inoue,  Tadashi Sato,  Minoru Sakamoto,  Atsuya Yamashita,  Kohji Moriishi,  Nobuyuki Enomoto, 
  • Pages: 51-63
  • First Published: 22 October 2018

Effect of luseogliflozin on hepatic fat content in type 2 diabetes patients with non-alcoholic fatty liver disease: A prospective, single-arm trial (LEAD trial)

Yoshio Sumida,  Kenta Murotani,  Miyoko Saito,  Atsuko Tamasawa,  Yusuke Osonoi,  Masashi Yoneda,  Takeshi Osonoi, 
  • Pages: 64-71
  • First Published: 27 July 2018

Accuracy of calprotectin using the Quantum Blue Reader for the diagnosis of spontaneous bacterial peritonitis in liver cirrhosis

Delphine Weil,  Alexandra Heurgue-Berlot,  Elisabeth Monnet,  Sophie Chassagne,  Jean-Paul Cervoni,  Thomas Feron,  Céline Grandvallet,  Emilie Muel,  Jean-Pierre Bronowicki,  Gérard Thiefin,  Vincent Di Martino,  Karine Bardonnet,  Thierry Thévenot, 
  • Pages: 72-81
  • First Published: 07 August 2018

Effect of loop diuretics on skeletal muscle depletion in patients with liver cirrhosis

Tatsunori Hanai,  Makoto Shiraki,  Takao Miwa,  Satoshi Watanabe,  Kenji Imai,  Atsushi Suetsugu,  Koji Takai,  Hisataka Moriwaki,  Masahito Shimizu, 
  • Pages: 82-95
  • First Published: 29 August 2018

Prompt initiation of high-dose i.v. corticosteroids seems to prevent progression to liver failure in patients with original acute severe autoimmune hepatitis

Kalliopi Zachou,  Pinelopi Arvaniti,  Kalliopi Azariadis,  Vasiliki Lygoura,  Nikolaos K. Gatselis,  Aggeliki Lyberopoulou,  George K. Koukoulis,  George N. Dalekos, 
  • Pages: 96-104
  • First Published: 24 September 2018

Analysis of 307 cases with drug-induced liver injury between 2010 and 2018 in Japan

Mitsuhiko Aiso,  Hajime Takikawa,  Keiji Tsuji,  Tatehiro Kagawa,  Masaaki Watanabe,  Atsushi Tanaka,  Ken Sato,  Shotaro Sakisaka,  Yoichi Hiasa,  Yoshiyuki Takei,  Hiromasa Ohira,  Minoru Ayada,  Etsuko Hashimoto,  Shuichi Kaneko,  Yoshiyuki Ueno,  Kenji Ohmoto,  Akinobu Takaki,  Takuji Torimura,  Yasushi Matsuzaki,  Kazuto Tajiri,  Masashi Yoneda,  Takayoshi Ito,  Naoya Kato,  Kenichi Ikejima,  Satoshi Mochida,  Hiroshi Yasuda,  Naoya Sakamoto, 
  • Pages: 105-110
  • First Published: 22 November 2018

Short Communication

Open Access

Therapeutic potential of lenvatinib for unresectable hepatocellular carcinoma in clinical practice: Multicenter analysis

Atsushi Hiraoka,  Takashi Kumada,  Kazuya Kariyama,  Koichi Takaguchi,  Ei Itobayashi,  Noritomo Shimada,  Kazuto Tajiri,  Kunihiko Tsuji,  Toru Ishikawa,  Hironori Ochi,  Masashi Hirooka,  Akemi Tsutsui,  Hiroshi Shibata,  Toshifumi Tada,  Hidenori Toyoda,  Kazuhiro Nouso,  Kouji Joko,  Yoichi Hiasa,  Kojiro Michitaka, On behalf of the Real-life Practice Experts for HCC (RELPEC) Study Group and the HCC 48 Group (hepatocellular carcinoma experts from 48 clinics in Japan) , 
  • Pages: 111-117
  • First Published: 24 August 2018

Letter to the Editor

Re-examination using newly proposed diagnostic criteria of acute-on-chronic liver failure in Japan

Shunsuke Nojiri,  Atsunori Tsuchiya,  Shuji Terai, 
  • Pages: 118-119
  • First Published: 07 August 2018