• Issue

    American Journal of Reproductive Immunology: Volume 78, Issue 5

    November 2017

COVER

Free Access

Cover

  • First Published: 15 October 2017
Cover

Front cover: The cover image, by Sejin Ahn et al., is based on the Original Article Identification of genes dysregulated by elevation of microRNA-210 levels in human trophoblasts cell line, Swan 71, DOI: 10.1111/aji.12722.

ISSUE INFORMATION

Free Access

Issue Information

  • First Published: 15 October 2017

TECHNICAL REPORT

A novel in vitro model of villitis of unknown etiology demonstrates altered placental hormone and cytokine profile

  • First Published: 06 July 2017
A novel in vitro model of villitis of unknown etiology demonstrates altered placental hormone and cytokine profile

In an in vitro model of villitis of unknown etiology maternal T cells can be seen invading villus tissue explants (A). Maternal T cells labeled with Cell Tracker fluorescence (B and C) are observed in the intervillus space. (D) Control explant cultured without T cells.

IMMUNOLOGICAL FACTORS IN PREGNANCY

Increased expression of resistin in ectopic endometrial tissue of women with endometriosis

  • First Published: 06 July 2017
Increased expression of resistin in ectopic endometrial tissue of women with endometriosis

Resistin mRNA expression is significantly higher in ectopic endometrial tissues of patients with endometriosis than in eutopic endometrial tissues of women without disease.

MUCOSAL IMMUNITY

Intrauterine delivery of subunit vaccines induces a systemic and mucosal immune response in rabbits

  • First Published: 03 August 2017
Intrauterine delivery of subunit vaccines induces a systemic and mucosal immune response in rabbits

To evaluate the comparative immuno-repressiveness of the upper genital tract, subunit vaccines composed a tri-adjuvant combo with either Ovalbumin, truncated glycoprotein D or parvovirus-thioredoxin fusion protein, were delivered either via the intramuscular (IM) or intrauterine (IU) routes. The resulting antigen specific serum titers suggest both delivery sites are equally responsive.