• Issue

    Journal of Cellular and Molecular Medicine: Volume 24, Issue 1

    1-1156
    January 2020
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ISSUE INFORMATION

Free Access

Issue Information

  • Pages: 1-3
  • First Published: 26 December 2019

REVIEWS

Open Access

TRPM2 channel: A novel target for alleviating ischaemia-reperfusion, chronic cerebral hypo-perfusion and neonatal hypoxic-ischaemic brain damage

Chendi Mai,  Harneet Mankoo,  Linyu Wei,  Xinfang An,  Chaokun Li,  Dongliang Li,  Lin-Hua Jiang, 
  • Pages: 4-12
  • First Published: 30 September 2019
Open Access

Crosstalk between cancer-associated fibroblasts and immune cells in cancer

Yuanyuan An,  Fengtian Liu,  Ying Chen,  Qing Yang, 
  • Pages: 13-24
  • First Published: 23 October 2019
Open Access

Melatonin preconditioning is an effective strategy for mesenchymal stem cell-based therapy for kidney disease

Lingfei Zhao,  Chenxia Hu,  Ping Zhang,  Hua Jiang,  Jianghua Chen, 
  • Pages: 25-33
  • First Published: 20 November 2019
Open Access

The multifaceted role of CARD9 in inflammatory bowel disease

Ping Luo,  Zhiwen Yang,  Bin Chen,  Xiaoming Zhong, 
  • Pages: 34-39
  • First Published: 06 November 2019
Open Access

Pre-treatments enhance the therapeutic effects of mesenchymal stem cells in liver diseases

Chenxia Hu,  Zhongwen Wu,  Lanjuan Li, 
  • Pages: 40-49
  • First Published: 06 November 2019

ORIGINAL ARTICLES

Open Access

Chelerythrine induces apoptosis via ROS-mediated endoplasmic reticulum stress and STAT3 pathways in human renal cell carcinoma

Hongchao He,  Ran Zhuo,  Jun Dai,  Xiaojing Wang,  Xin Huang,  Haofei Wang,  Danfeng Xu, 
  • Pages: 50-60
  • First Published: 30 September 2019
Open Access

Oridonin prevents insulin resistance–mediated cognitive disorder through PTEN/Akt pathway and autophagy in minimal hepatic encephalopathy

Fangfang Wen,  Weishan Zhuge,  Jian Wang,  Xiaoai Lu,  Ruimin You,  Leping Liu,  Qichuan Zhuge,  Saidan Ding, 
  • Pages: 61-78
  • First Published: 30 September 2019
Open Access

LNRLMI: Linear neighbour representation for predicting lncRNA-miRNA interactions

Leon Wong,  Yu-An Huang,  Zhu-Hong You,  Zhan-Heng Chen,  Mei-Yuan Cao, 
  • Pages: 79-87
  • First Published: 30 September 2019
Open Access

Characterization and modulation of microglial phenotypes in an animal model of severe sepsis

Monique Michels,  Mariane Rocha Abatti,  Pricila Ávila,  Andriele Vieira,  Heloisa Borges,  Celso Carvalho Junior,  Diogo Wendhausen,  Juciano Gasparotto,  Camila Tiefensee Ribeiro,  José Claudio Fonseca Moreira,  Daniel Pens Gelain,  Felipe Dal-Pizzol, 
  • Pages: 88-97
  • First Published: 26 October 2019
Open Access

Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells

Haoming Lu,  Ying Feng,  Yilin Hu,  Yibing Guo,  Yifei Liu,  Qinsheng Mao,  Wanjiang Xue, 
  • Pages: 98-113
  • First Published: 05 November 2019
Open Access

S100-A9 protein in exosomes derived from follicular fluid promotes inflammation via activation of NF-κB pathway in polycystic ovary syndrome

Han Li,  Xin Huang,  Xinwen Chang,  Julei Yao,  Qizhi He,  Zhijun Shen,  Yazhong Ji,  Kai Wang, 
  • Pages: 114-125
  • First Published: 30 September 2019
Open Access

Nuclear localization of the tyrosine kinase BMX mediates VEGFR2 expression

Tingting Liu,  Yonghao Li,  Hong Su,  Haifeng Zhang,  Dennis Jones,  Huanjiao Jenny Zhou,  Weidong Ji,  Wang Min, 
  • Pages: 126-138
  • First Published: 23 October 2019
Open Access

Matrix metalloproteases and TIMPs as prognostic biomarkers in breast cancer patients treated with radiotherapy: A pilot study

María Auxiliadora Olivares-Urbano,  Carmen Griñán-Lisón,  Mercedes Zurita,  Rosario del Moral,  Sandra Ríos-Arrabal,  Francisco Artacho-Cordón,  Juan Pedro Arrebola,  Amanda Rocío González,  Josefa León,  Juan Antonio Marchal,  María Isabel Núñez, 
  • Pages: 139-148
  • First Published: 30 September 2019
Open Access

Expression and functional analysis of lncRNAs in the hippocampus of immature rats with status epilepticus

Jing Gan,  Lingyi Huang,  Yi Qu,  Rong Luo,  Qianyun Cai,  Fengyan Zhao,  Dezhi Mu, 
  • Pages: 149-159
  • First Published: 18 November 2019
Open Access

Deletion of the FHL2 gene attenuates intima-media thickening in a partially ligated carotid artery ligated mouse model

Chi-Yu Chen,  Hsiao-Ya Tsai,  Shih-Hung Tsai,  Pao-Hsien Chu,  Po-Hsun Huang,  Jaw-Wen Chen,  Shing-Jong Lin, 
  • Pages: 160-173
  • First Published: 12 November 2019
Open Access

Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of Saikosaponin A

Juanjuan Guo,  Feng Zhang,  Jifang Gao,  Xinyuan Guan,  Beiyun Liu,  Xiaoge Wang,  Zhaoyu Qin,  Kuanxiao Tang,  Shilian Liu, 
  • Pages: 174-188
  • First Published: 24 November 2019
Open Access

SARI suppresses colitis-associated cancer development by maintaining MCP-1-mediated tumour-associated macrophage recruitment

Lei Dai,  Yi Liu,  Yuan Yin,  Junshu Li,  Zhexu Dong,  Na Chen,  Lin Cheng,  Huiling Wang,  Chao Fang,  Yi Lin,  Gang Shi,  Hantao Zhang,  Ping Fan,  Xiaolan Su,  Shuang Zhang,  Yang Yang,  Lie Yang,  Wei Huang,  Zongguang Zhou,  Dechao Yu,  Hongxin Deng, 
  • Pages: 189-201
  • First Published: 02 October 2019
Open Access

Knockdown of long non-coding RNA LINC00176 suppresses ovarian cancer progression by BCL3-mediated down-regulation of ceruloplasmin

Lan Dai,  Jixiang Niu,  Yanli Feng, 
  • Pages: 202-213
  • First Published: 30 October 2019
Open Access

Glycyrrhizin mitigates radiation-induced acute lung injury by inhibiting the HMGB1/TLR4 signalling pathway

Lei Zheng,  Qian Zhu,  Cheng Xu,  Min Li,  Huan Li,  Pei-Qiang Yi,  Fei-Fei Xu,  Lu Cao,  Jia-Yi Chen, 
  • Pages: 214-226
  • First Published: 27 October 2019
Open Access

MiR-590-3p regulates proliferation, migration and collagen synthesis of cardiac fibroblast by targeting ZEB1

Xiaolong Yuan,  Jinchun Pan,  Lijuan Wen,  Baoyong Gong,  Jiaqi Li,  Hongbin Gao,  Weijiang Tan,  Shi Liang,  Hao Zhang,  Xilong Wang, 
  • Pages: 227-237
  • First Published: 01 November 2019
Open Access

LncRNA HOXA11-AS regulates calcium oxalate crystal–induced renal inflammation via miR-124-3p/MCP-1

Yinhui Li,  Guiling Yan,  Jie Zhang,  Wei Chen,  Tao Ding,  Yupeng Yin,  Minghan Li,  Yiqing Zhu,  Shuhan Sun,  Ji Hang Yuan,  Zhiyong Guo, 
  • Pages: 238-249
  • First Published: 03 November 2019
Open Access

Long noncoding RNA TUG1 contributes to cerebral ischaemia/reperfusion injury by sponging mir-145 to up-regulate AQP4 expression

Weifeng Shan,  Wei Chen,  Xian Zhao,  Aijie Pei,  Manli Chen,  Yang Yu,  Yueying Zheng,  Shengmei Zhu, 
  • Pages: 250-259
  • First Published: 11 November 2019
Open Access

Macrophage autophagy regulates mitochondria-mediated apoptosis and inhibits necrotic core formation in vulnerable plaques

Qingqing Xiao,  Xinyu Che,  Bin Cai,  Zhenyu Tao,  Hengyuan Zhang,  Qin Shao,  Jun Pu, 
  • Pages: 260-275
  • First Published: 29 October 2019
Open Access

Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence

Shupei Wei,  Lili Liu,  Zhiyu Chen,  Wenli Yin,  Yingzi Liu,  Qianying Ouyang,  Feiyue Zeng,  Yingjie Nie,  Tao Chen, 
  • Pages: 276-284
  • First Published: 20 November 2019
Open Access

Genetic risk scores to predict the prognosis of chronic heart failure patients in Chinese Han

Shiyang Li,  Yang Sun,  Senlin Hu,  Dong Hu,  Chenze Li,  Lei Xiao,  Yanghui Chen,  Huihui Li,  Guanglin Cui,  Dao Wen Wang, 
  • Pages: 285-293
  • First Published: 31 October 2019
Open Access

Wuzang Wenyang Huayu decoction regulates differentially expressed transcripts in the rats' hippocampus after cerebral hypoperfusion

Meng Xia,  Ziyun Ruan,  Ben Chen,  Yunqiao Wang,  Zengzi Zhou,  Shiding Ren,  Lin Wu,  Nong Tang, 
  • Pages: 294-303
  • First Published: 09 November 2019
Open Access

Long non-coding RNA TNRC6C-AS1 promotes methylation of STK4 to inhibit thyroid carcinoma cell apoptosis and autophagy via Hippo signalling pathway

Xinzhi Peng,  Chengcheng Ji,  Langping Tan,  Shaojian Lin,  Yue Zhu,  Miaoyun Long,  Dingyuan Luo,  Honghao Li, 
  • Pages: 304-316
  • First Published: 27 October 2019
Open Access

Deficiency of Macf1 in osterix expressing cells decreases bone formation by Bmp2/Smad/Runx2 pathway

Wu-Xia Qiu,  Xiao-Li Ma,  Xiao Lin,  Fan Zhao,  Di-Jie Li,  Zhi-Hao Chen,  Ke-Wen Zhang,  Ru Zhang,  Pai Wang,  Yun-Yun Xiao,  Zhi-Ping Miao,  Kai Dang,  Xiao-Yang Wu,  Ai-Rong Qian, 
  • Pages: 317-327
  • First Published: 11 November 2019
Deficiency of Macf1 in osterix expressing cells decreases bone formation by Bmp2/Smad/Runx2 pathway

Deficiency of Macf1 inhibits bone formation by attenuating Bmp2/Smad/Runx2 signalling in osteoblasts. Macf1f/fOsx-Cre mice showed decreased bone mass, deteriorated bone microarchitecture and impaired bone strength. We demonstrated that Macf1 affected differentiation of primary osteoblasts through Bmp2/Smad/Runx2 signalling pathway.

Open Access

Manganese activates autophagy to alleviate endoplasmic reticulum stress–induced apoptosis via PERK pathway

Chang Liu,  Dong-Ying Yan,  Can Wang,  Zhuo Ma,  Yu Deng,  Wei Liu,  Bin Xu, 
  • Pages: 328-341
  • First Published: 22 October 2019
Open Access

Circular RNA USP1 regulates the permeability of blood-tumour barrier via miR-194-5p/FLI1 axis

Yang Gao,  Peiqi Wu,  Yawen Ma,  Yixue Xue,  Yunhui Liu,  Jian Zheng,  Xiaobai Liu,  Qianru He,  Jun Ma,  Libo Liu,  Ping Wang, 
  • Pages: 342-355
  • First Published: 26 October 2019
Open Access

circFBXL5 promotes breast cancer progression by sponging miR-660

Huamao Zhou,  Guohui Tang,  Mi Zhao,  Liming Xie,  Yuanjie Xie,  Zhiwei Zhang,  Xiusheng He, 
  • Pages: 356-361
  • First Published: 15 November 2019
Open Access

Cosmc overexpression enhances malignancies in human colon cancer

Tianbo Gao,  Tan Du,  Xin Hu,  Xichen Dong,  Lina Li,  Yakun Wang,  Jian Liu,  Lijie Liu,  Tao Gu,  Tao Wen, 
  • Pages: 362-370
  • First Published: 21 October 2019
Open Access

Interleukin-38 alleviates cardiac remodelling after myocardial infarction

Yuzhen Wei,  Yin Lan,  Yucheng Zhong,  Kunwu Yu,  Wenbin Xu,  Ruirui Zhu,  Haitao Sun,  Yan Ding,  Yue Wang,  Qiutang Zeng, 
  • Pages: 371-384
  • First Published: 20 November 2019
Open Access

Toll-like receptor 4 regulates spontaneous intestinal tumorigenesis by up-regulating IL-6 and GM-CSF

Yun-Jie Shi,  Quan-Quan Zhao,  Xiao-Shuang Liu,  Su-He Dong,  Ji-Fu E,  Xu Li,  Cong Liu,  Hao Wang, 
  • Pages: 385-397
  • First Published: 25 October 2019
Open Access

MiR-485-3p modulates neural stem cell differentiation and proliferation via regulating TRIP6 expression

Juxian Gu,  Rusheng Shao,  Meng Li,  Qiuyue Yan,  Hongwei Hu, 
  • Pages: 398-404
  • First Published: 15 November 2019
Open Access

miR-148a suppresses inflammation in lipopolysaccharide-induced endometritis

Kangfeng Jiang,  Jing Yang,  Chao Yang,  Tao Zhang,  Aftab Shaukat,  Xiaoyan Yang,  Ailing Dai,  Haichong Wu,  Ganzhen Deng, 
  • Pages: 405-417
  • First Published: 22 November 2019
Open Access

Pan-cancer RNA-seq data stratifies tumours by some hallmarks of cancer

F. Graeme Frost,  Praveen F. Cherukuri,  Samuel Milanovich,  Cornelius F. Boerkoel, 
  • Pages: 418-430
  • First Published: 15 November 2019
Open Access

Haemin pre-treatment augments the cardiac protection of mesenchymal stem cells by inhibiting mitochondrial fission and improving survival

Rui Deng,  Yaming Liu,  Haiwei He,  Hao Zhang,  Chenling Zhao,  Zhen Cui,  Yimei Hong,  Xin Li,  Fang Lin,  Dongsheng Yuan,  Xiaoting Liang,  Yuelin Zhang, 
  • Pages: 431-440
  • First Published: 29 October 2019
Open Access

LncRNA DLEU2 accelerates the tumorigenesis and invasion of non–small cell lung cancer by sponging miR-30a-5p

Weiming Wu,  Yonghong Zhao,  Erji Gao,  Yang Li,  Xiang Guo,  Tiancheng Zhao,  Weiwei He,  Huibiao Zhang, 
  • Pages: 441-450
  • First Published: 13 November 2019
Open Access

Down-regulated lncRNA HOTAIR alleviates polycystic ovaries syndrome in rats by reducing expression of insulin-like growth factor 1 via microRNA-130a

Bin Jiang,  Min Xue,  Dabao Xu,  Jiayu Song,  Shujuan Zhu, 
  • Pages: 451-464
  • First Published: 16 November 2019
Open Access

Role of VEGFR-1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

Maria Grazia Atzori,  Claudia Ceci,  Federica Ruffini,  Mauro Trapani,  Maria Luisa Barbaccia,  Lucio Tentori,  Stefania D'Atri,  Pedro Miguel Lacal,  Grazia Graziani, 
  • Pages: 465-475
  • First Published: 23 November 2019
Open Access

Low-level laser therapy 810-nm up-regulates macrophage secretion of neurotrophic factors via PKA-CREB and promotes neuronal axon regeneration in vitro

Jiawei Zhang,  Jiakai Sun,  Qiao Zheng,  Xueyu Hu,  Zhe Wang,  Zhuowen Liang,  Kun Li,  Jiwei Song,  Tan Ding,  Xuefeng Shen,  Jianxin Zhang,  Lin Qiao, 
  • Pages: 476-487
  • First Published: 31 October 2019
Open Access

Protective mechanism of SIRT1 on Hcy-induced atrial fibrosis mediated by TRPC3

Lu Han,  Yanhua Tang,  Shaochuan Li,  Yanqing Wu,  Xiaoshu Chen,  Qinghua Wu,  Kui Hong,  Juxiang Li, 
  • Pages: 488-510
  • First Published: 04 November 2019
Open Access

Proteomics of epicardial adipose tissue in patients with heart failure

Lei Zhao,  Zongsheng Guo,  Pan Wang,  Meili Zheng,  Xiaoyan Yang,  Ye Liu,  Zheng Ma,  Mulei Chen,  Xinchun Yang, 
  • Pages: 511-520
  • First Published: 31 October 2019
Open Access

LncRNA NKILA integrates RXFP1/AKT and NF-κB signalling to regulate osteogenesis of mesenchymal stem cells

Ying Zhang,  Xiangyang Cao,  Peifeng Li,  Yanan Fan,  Leilei Zhang,  Xianghao Ma,  Ruibo Sun,  Youwen Liu,  Wuyin Li, 
  • Pages: 521-529
  • First Published: 28 October 2019
Open Access

TNIP1-mediated TNF-α/NF-κB signalling cascade sustains glioma cell proliferation

Qingchun Lei,  Huan Gu,  Lei Li,  Tingting Wu,  Wentao Xie,  Meizhang Li,  Ninghui Zhao, 
  • Pages: 530-538
  • First Published: 05 November 2019
Open Access

Medial calcification in the arterial wall of smooth muscle cell-specific Smpd1 transgenic mice: A ceramide-mediated vasculopathy

Owais M. Bhat,  Xinxu Yuan,  Chad Cain,  Fadi N. Salloum,  Pin-Lan Li, 
  • Pages: 539-553
  • First Published: 19 November 2019
Open Access

SP1-mediated lncRNA PVT1 modulates the proliferation and apoptosis of lens epithelial cells in diabetic cataract via miR-214-3p/MMP2 axis

Jun Yang,  Shaozhen Zhao,  Fang Tian, 
  • Pages: 554-561
  • First Published: 21 November 2019
Open Access

p53-dependent transcriptional suppression of BAG3 protects cells against metabolic stress via facilitation of p53 accumulation

Jia-Mei Wang,  Bao-Qin Liu,  Zhen-Xian Du,  Chao Li,  Jia Sun,  Jing Yan,  Jing-Yi Jiang,  Hua-Qin Wang, 
  • Pages: 562-572
  • First Published: 28 October 2019
Open Access

In silico prediction of potential miRNA-disease association using an integrative bioinformatics approach based on kernel fusion

Na-Na Guan,  Chun-Chun Wang,  Li Zhang,  Li Huang,  Jian-Qiang Li,  Xue Piao, 
  • Pages: 573-587
  • First Published: 20 November 2019
Open Access

Pancreatic cancer cell–derived exosomal microRNA-27a promotes angiogenesis of human microvascular endothelial cells in pancreatic cancer via BTG2

Dan Shang,  Chao Xie,  Jin Hu,  Jinru Tan,  Yufeng Yuan,  Zhisu Liu,  Zhiyong Yang, 
  • Pages: 588-604
  • First Published: 13 November 2019
Open Access

An EMT-related gene signature for the prognosis of human bladder cancer

Rui Cao,  Lushun Yuan,  Bo Ma,  Gang Wang,  Wei Qiu,  Ye Tian, 
  • Pages: 605-617
  • First Published: 28 October 2019
Open Access

CBX4 promotes the proliferation and metastasis via regulating BMI-1 in lung cancer

Changpeng Hu,  Qian Zhang,  Qin Tang,  Huyue Zhou,  Wuyi Liu,  Jingbin Huang,  Yali Liu,  Qin Wang,  Jing Zhang,  Min Zhou,  Fangfang Sheng,  Wenjing Lai,  Jing Tian,  Guobing Li,  Rong Zhang, 
  • Pages: 618-631
  • First Published: 13 November 2019
Open Access

VEGF signalling enhances lesion burden in KRIT1 deficient mice

Peter V. DiStefano,  Angela J. Glading, 
  • Pages: 632-639
  • First Published: 20 November 2019
Open Access

Exosomes from human urine-derived stem cells enhanced neurogenesis via miR-26a/HDAC6 axis after ischaemic stroke

Xiaozheng Ling,  Guowei Zhang,  Yuguo Xia,  Qingwei Zhu,  Juntao Zhang,  Qing Li,  Xin Niu,  Guowen Hu,  Yunlong Yang,  Yang Wang,  Zhifeng Deng, 
  • Pages: 640-654
  • First Published: 31 October 2019
Open Access

Melittin inhibits proliferation, migration and invasion of bladder cancer cells by regulating key genes based on bioinformatics and experimental assays

Jie Yao,  Zhan Zhang,  Sheng Li,  Bai Li,  Xing-Huan Wang, 
  • Pages: 655-670
  • First Published: 05 November 2019

Open Access

Dual regulation of microglia and neurons by Astragaloside IV-mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury

Jialiang Lin,  Xiangxiang Pan,  Chongan Huang,  Mingbao Gu,  Ximiao Chen,  Xuanqi Zheng,  Zhenxuan Shao,  Sunli Hu,  Ben Wang,  Hao Lin,  Yaosen Wu,  Naifeng Tian,  Yan Wu,  Weiyang Gao,  Yifei Zhou,  Xiaolei Zhang,  Xiangyang Wang, 
  • Pages: 671-685
  • First Published: 01 November 2019
Open Access

Inhibition of microRNA-222 up-regulates TIMP3 to promotes osteogenic differentiation of MSCs from fracture rats with type 2 diabetes mellitus

Chenyi Jiang,  Wenyang Xia,  Tianyi Wu,  Chenhao Pan,  Haojie Shan,  Feng Wang,  Zubin Zhou,  Xiaowei Yu, 
  • Pages: 686-694
  • First Published: 06 November 2019
Open Access

Knockout of beta-2 microglobulin reduces stem cell-induced immune rejection and enhances ischaemic hindlimb repair via exosome/miR-24/Bim pathway

Yuqing Zhang,  Yanli Wang,  Lianbo Shao,  Xiangbin Pan,  Chun Liang,  Bin Liu,  Yu Zhang,  Wenping Xie,  Bing Yan,  Feng Liu,  Xi-yong Yu,  Yangxin Li, 
  • Pages: 695-710
  • First Published: 15 November 2019
Open Access

Four transcription profile–based models identify novel prognostic signatures in oesophageal cancer

Tongyan Liu,  Panqi Fang,  Chencheng Han,  Zhifei Ma,  Weizhang Xu,  Wenjia Xia,  Jingwen Hu,  Youtao Xu,  Lin Xu,  Rong Yin,  Siwei Wang,  Qin Zhang, 
  • Pages: 711-721
  • First Published: 19 November 2019
Open Access

Effect of (R)-salbutamol on the switch of phenotype and metabolic pattern in LPS-induced macrophage cells

Shanping Wang,  Fei Liu,  Keai Sinn Tan,  Hooi-Leng Ser,  Loh Teng-Hern Tan,  Learn-Han Lee,  Wen Tan, 
  • Pages: 722-736
  • First Published: 03 November 2019
Open Access

LncRNA ACART protects cardiomyocytes from apoptosis by activating PPAR-γ/Bcl-2 pathway

Hao Wu,  Haixia Zhu,  Yuting Zhuang,  Jifan Zhang,  Xin Ding,  Linfeng Zhan,  Shenjian Luo,  Qi Zhang,  Fei Sun,  Mingyu Zhang,  Zhenwei Pan,  Yanjie Lu, 
  • Pages: 737-746
  • First Published: 20 November 2019
Open Access

MicroRNA-1275 induces radiosensitization in oesophageal cancer by regulating epithelial-to-mesenchymal transition via Wnt/β-catenin pathway

Congying Xie,  Youyi Wu,  Zhenghua Fei,  Ya Fang,  Shenlan Xiao,  Huafang Su, 
  • Pages: 747-759
  • First Published: 15 November 2019

Open Access

α-Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades

Yu Shi,  Yangwei Fan,  Yuan Hu,  Jiayu Jing,  Chuying Wang,  Yinying Wu,  Qianqian Geng,  Xuyuan Dong,  Enxiao Li,  Danfeng Dong, 
  • Pages: 760-771
  • First Published: 25 November 2019
Open Access

LncRNA SPRY4-IT1 regulates breast cancer cell stemness through competitively binding miR-6882-3p with TCF7L2

Xinyue Song,  Xiaoxue Zhang,  Xinnan Wang,  Lianze Chen,  Longyang Jiang,  Ang Zheng,  Ming Zhang,  Lin Zhao,  Minjie Wei, 
  • Pages: 772-784
  • First Published: 17 November 2019
Open Access

l-tetrahydropalmatine suppresses osteoclastogenesis in vivo and in vitro via blocking RANK-TRAF6 interactions and inhibiting NF-κB and MAPK pathways

Xin Zhi,  Lipeng Wang,  Huiwen Chen,  Chao Fang,  Jin Cui,  Yan Hu,  Liehu Cao,  Weizong Weng,  Qirong Zhou,  Longjuan Qin,  Hongyuan Song,  Yajun Wang,  Yao Wang,  Hao Jiang,  Xiaoqun Li,  Sicheng Wang,  Xiao Chen,  Jiacan Su, 
  • Pages: 785-798
  • First Published: 14 November 2019
Open Access

Circular RNA circFOXO3 promotes prostate cancer progression through sponging miR-29a-3p

Zhe Kong,  Xuechao Wan,  Yali Lu,  Yingyi Zhang,  Yan Huang,  Yi Xu,  Yajuan Liu,  Peiqing Zhao,  Xinxin Xiang,  Liang Li,  Yao Li, 
  • Pages: 799-813
  • First Published: 16 November 2019
Open Access

Integrative transcriptomic and proteomic analysis reveals CD9/ITGA4/PI3K-Akt axis mediates trabecular meshwork cell apoptosis in human glaucoma

Junwei Yan,  Xuejiao Yang,  Xuefei Jiao,  Xian Yang,  Mingjin Guo,  Yunqing Chen,  Lu Zhan,  Wenshi Chen, 
  • Pages: 814-829
  • First Published: 03 November 2019
Open Access

A new FGFR inhibitor disrupts the TGF-β1-induced fibrotic process

Mi-Hyoung Kim,  Seung-Youn Jung,  Kyung-Hee Song,  Jeong-In Park,  Jiyeon Ahn,  Eun-Ho Kim,  Jong Kuk Park,  Sang-Gu Hwang,  Hee-Jong Woo,  Jie-Young Song, 
  • Pages: 830-840
  • First Published: 06 November 2019
Open Access

MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway

Jianya He,  Wen Ye,  Ni Kou,  Kang Chen,  Bai Cui,  Xiaohong Zhang,  Shuhai Hu,  Tingjiao Liu,  Lan Kang,  Xiaojie Li, 
  • Pages: 841-849
  • First Published: 03 November 2019
Open Access

Dexmedetomidine post-treatment attenuates cardiac ischaemia/reperfusion injury by inhibiting apoptosis through HIF-1α signalling

Ke Peng,  Wei-rong Chen,  Fan Xia,  Hong Liu,  Xiao-wen Meng,  Juan Zhang,  Hua-yue Liu,  Zheng-yuan Xia,  Fu-hai Ji, 
  • Pages: 850-861
  • First Published: 03 November 2019
Open Access

CYP2J2/EET reduces vulnerability to atrial fibrillation in chronic pressure overload mice

Xuguang Li,  Feng Zhu,  Weidong Meng,  Feng Zhang,  Jiang Hong,  Guobing Zhang,  Fang Wang, 
  • Pages: 862-874
  • First Published: 20 November 2019
Open Access

Formononetin, J1 and J2 have different effects on endothelial cells via EWSAT1-TRAF6 and its downstream pathway

Xin Li,  Chen Huang,  Cheng Liang Sui,  Chun Mei Liang,  Guang Ying Qi,  Qian Yao Ren,  Jian Chen,  Zhao Quan Huang, 
  • Pages: 875-885
  • First Published: 19 November 2019
Open Access

N-acetylcysteine prevents oxidized low-density lipoprotein-induced reduction of MG53 and enhances MG53 protective effect on bone marrow stem cells

Xin Li,  Meng Jiang,  Tao Tan,  Chandrakala A. Narasimhulu,  Yuan Xiao,  Hong Hao,  Yuqi Cui,  Jia Zhang,  Lingjuan Liu,  Chunlin Yang,  Yixi Li,  Jianjie Ma,  Catherine M. Verfaillie,  Sampath Parthasarathy,  Hua Zhu,  Zhenguo Liu, 
  • Pages: 886-898
  • First Published: 19 November 2019
Open Access

Down-regulation of the mitochondrial i-AAA protease Yme1L induces muscle atrophy via FoxO3a and myostatin activation

Yoo Jeong Lee,  Gyu Hee Kim,  Sang Ick Park,  Joo Hyun Lim, 
  • Pages: 899-909
  • First Published: 14 November 2019
Open Access

Inhibition of miR-21 alleviated cardiac perivascular fibrosis via repressing EndMT in T1DM

Qianqian Li,  Yufeng Yao,  Shumei Shi,  Mengchen Zhou,  Yingchao Zhou,  Mengru Wang,  Jeng-Jiann Chiu,  Zhengrong Huang,  Weili Zhang,  Min Liu,  Qing Wang,  Xin Tu, 
  • Pages: 910-920
  • First Published: 03 November 2019
Open Access

y+LAT1 and y+LAT2 contribution to arginine uptake in different human cell models: Implications in the pathophysiology of Lysinuric Protein Intolerance

Bianca Maria Rotoli,  Amelia Barilli,  Rossana Visigalli,  Francesca Ferrari,  Valeria Dall’Asta, 
  • Pages: 921-929
  • First Published: 09 November 2019
Open Access

The pro-inflammatory effect of NR4A3 in osteoarthritis

Chiyuan Ma,  Lingyun Wu,  Lu Song,  Yuzhe He,  Safwat Adel Abdo Moqbel,  Shigui Yan,  Kunkun Sheng,  Haobo Wu,  Jisheng Ran,  Lidong Wu, 
  • Pages: 930-940
  • First Published: 07 November 2019
Open Access

Celastrol exerts anti-inflammatory effect in liver fibrosis via activation of AMPK-SIRT3 signalling

Yuqin Wang,  Chunling Li,  Jingya Gu,  Chang Chen,  Jiaxin Duanmu,  Jing Miao,  Wenjuan Yao,  Jinhua Tao,  Mengjue Tu,  Biao Xiong,  Lingling Zhao,  Zhaoguo Liu, 
  • Pages: 941-953
  • First Published: 19 November 2019
Open Access

14-3-3ζ binds to and stabilizes phospho-beclin 1S295 and induces autophagy in hepatocellular carcinoma cells

Yufu Tang,  Yibing Zhang,  Shupeng Liu,  Zhongyi Sun,  Chunhui Wang,  Longfei Li,  Wenping Zhou,  Shuqun Cheng, 
  • Pages: 954-964
  • First Published: 11 November 2019
Open Access

The expression of miR-125b in Nrf2-silenced A549 cells exposed to hyperoxia and its relationship with apoptosis

Xiaoyue Zhang,  Xiaoyun Chu,  Xiaohui Gong,  Huilin Zhou,  Cheng Cai, 
  • Pages: 965-972
  • First Published: 12 November 2019
Open Access

Down-regulation of Suv39h1 attenuates neointima formation after carotid artery injury in diabetic rats

Jing Zhang,  Jian Yang,  Changwu Xu,  Qi Hu,  Jun Hu,  Jing Chen,  Hong Jiang, 
  • Pages: 973-983
  • First Published: 17 November 2019
Open Access

TPD7 inhibits the growth of cutaneous T cell lymphoma H9 cell through regulating IL-2R signalling pathway

Man Zhu,  Liu Yang,  Xianpeng Shi,  Zhengyan Gong,  Runze Yu,  Dongdong Zhang,  Yanmin Zhang,  Weina Ma, 
  • Pages: 984-995
  • First Published: 19 November 2019
Open Access

Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor

Jianbin Bi,  Jia Zhang,  Yifan Ren,  Zhaoqing Du,  Teng Li,  Tao Wang,  Lin Zhang,  Mengzhou Wang,  Zheng Wu,  Yi Lv,  Rongqian Wu, 
  • Pages: 996-1009
  • First Published: 07 November 2019
Open Access

Systematic screening identifies a 2-gene signature as a high-potential prognostic marker of undifferentiated pleomorphic sarcoma/myxofibrosarcoma

Qinsheng Hu,  Shijie Zhou,  Xuefeng Hu,  Hua Zhang,  Shishu Huang,  Yunbing Wang, 
  • Pages: 1010-1021
  • First Published: 19 November 2019
Open Access

Genistein-3′-sodium sulphonate protects against lipopolysaccharide-induced lung vascular endothelial cell apoptosis and acute lung injury via BCL-2 signalling

Lei Yi,  Mengling Chang,  Quanming Zhao,  Zengding Zhou,  Xiaoqin Huang,  Feng Guo,  Jingning Huan, 
  • Pages: 1022-1035
  • First Published: 22 November 2019
Open Access

G9α-dependent histone H3K9me3 hypomethylation promotes overexpression of cardiomyogenesis-related genes in foetal mice

Bohui Peng,  Xiao Han,  Chang Peng,  Xiaomei Luo,  Ling Deng,  Lixin Huang, 
  • Pages: 1036-1045
  • First Published: 19 November 2019

Open Access

CD8+ T cells exhaustion induced by myeloid-derived suppressor cells in myelodysplastic syndromes patients might be through TIM3/Gal-9 pathway

Jinglian Tao,  Dong Han,  Shan Gao,  Wei Zhang,  Hong Yu,  Pei Liu,  Rong Fu,  Lijuan Li,  Zonghong Shao, 
  • Pages: 1046-1058
  • First Published: 22 November 2019
Open Access

LIN28A gene polymorphisms modify neuroblastoma susceptibility: A four-centre case-control study

Rui-Xi Hua,  Zhenjian Zhuo,  Lili Ge,  Jinhong Zhu,  Li Yuan,  Chongfen Chen,  Jing Liu,  Jiwen Cheng,  Haixia Zhou,  Jiao Zhang,  Huimin Xia,  Xianwei Zhang,  Jing He, 
  • Pages: 1059-1066
  • First Published: 20 November 2019
Open Access

Up-regulation of DDIT4 predicts poor prognosis in acute myeloid leukaemia

Zhiheng Cheng,  Yifeng Dai,  Yifan Pang,  Yang Jiao,  Yan Liu,  Longzhen Cui,  Liang Quan,  Tingting Qian,  Tiansheng Zeng,  Chaozeng Si,  Wenhui Huang,  Jinghong Chen,  Ying Pang,  Xu Ye,  Jinlong Shi,  Lin Fu, 
  • Pages: 1067-1075
  • First Published: 21 November 2019
Open Access

IL-10 induces MC3T3-E1 cells differentiation towards osteoblastic fate in murine model

Yuan Xiong,  Chenchen Yan,  Lang Chen,  Yori Endo,  Yun Sun,  Wu Zhou,  Yiqiang Hu,  Liangcong Hu,  Dong Chen,  Hang Xue,  Bobin Mi,  Guohui Liu, 
  • Pages: 1076-1086
  • First Published: 21 November 2019

Open Access

Inhibition of cyclin-dependent kinase 7 down-regulates yes-associated protein expression in mesothelioma cells

Jinbai Miao,  Hiroyuki Kyoyama,  Luwei Liu,  Geraldine Chan,  Yucheng Wang,  Anatoly Urisman,  Yi-Lin Yang,  Shu Liu,  Zhidong Xu,  Hu Bin,  Hui Li,  David M. Jablons,  Liang You, 
  • Pages: 1087-1098
  • First Published: 21 November 2019
Open Access

LncRNA H19 ameliorates myocardial infarction-induced myocardial injury and maladaptive cardiac remodelling by regulating KDM3A

Bo-fang Zhang,  Hong Jiang,  Jing Chen,  Qi Hu,  Shuo Yang,  Xiao-pei Liu,  Gen Liu, 
  • Pages: 1099-1115
  • First Published: 21 November 2019

Open Access

Notch3 promotes 3T3-L1 pre-adipocytes differentiation by up-regulating the expression of LARS to activate the mTOR pathway

Yuxian Guo,  Junyu Tan,  Wei Xiong,  Shuzhao Chen,  Liping Fan,  Yaochen Li, 
  • Pages: 1116-1127
  • First Published: 21 November 2019
Open Access

Fibroblast growth factor-2/platelet-derived growth factor enhances atherosclerotic plaque stability

Yang Mao,  Xiao Qiong Liu,  Yu Song,  Chun Gang Zhai,  Xing Li Xu,  Lei Zhang,  Yun Zhang, 
  • Pages: 1128-1140
  • First Published: 21 November 2019

SHORT COMMUNICATIONS

Open Access

DDX49 is a novel biomarker and therapeutic target for lung cancer metastases

Xiaojuan Lian,  Debing Xiang,  Chunfang Peng,  Jiangyan Chen,  Maojun Liao,  Guiyin Sun,  Zhimin Zhang, 
  • Pages: 1141-1145
  • First Published: 20 November 2019
Open Access

Clinical significance of circulating microRNAs as diagnostic biomarkers for coronary artery disease

Lei Zhang,  Yuan Zhang,  Sheng Xue,  Han Ding,  Yu Wang,  Hongzhao Qi,  Yin Wang,  Wenjie Zhu,  Peifeng Li, 
  • Pages: 1146-1150
  • First Published: 11 November 2019
Open Access

Role of melatonin as an SIRT1 enhancer in chronic obstructive pulmonary disease induced by cigarette smoke

Na-Rae Shin,  Je-Won Ko,  Jong-Choon Kim,  Gunhyuk Park,  Sung-Hwan Kim,  Min-Seok Kim,  Joong-Sun Kim,  In-Sik Shin, 
  • Pages: 1151-1156
  • First Published: 25 November 2019